DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELOVL and Elovl7

DIOPT Version :9

Sequence 1:	NP_649754.1	Gene:	ELOVL / 40943	FlyBaseID:	FBgn0037534	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_083277.3	Gene:	Elovl7 / 74559	MGIID:	1921809	Length:	281	Species:	Mus musculus

Alignment Length:	274	Identity:	145/274 - (52%)
Similarity:	178/274 - (64%)	Gaps:	7/274 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FYDGWRDLMDNKSDPRTRDYPLMSSPFPTIAISLTYAYIVKVLGPKLMENRKPFELRKVLIVYNA 71
            |||.|  :.|  :|||..||.|||||.|...|...|.|.|..||||||||||||||:|.:|.||.
Mouse    13 FYDNW--IKD--ADPRVEDYLLMSSPLPQTIILGLYVYFVTSLGPKLMENRKPFELKKAMITYNF 73

  Fly    72 AQVIFSAWLFYESCIGGWLNGYNLRCEPVNYSYSPKAIRTAEGCWWYYFSKFTEFFDTFFFVMRK 136
            ..|:||.::.||..:.||..||:.||:.|:||.||:|:|....||.||||||.|..||.|||:||
Mouse    74 FIVLFSVYMCYEFVMSGWGTGYSFRCDIVDYSQSPRAMRMVHTCWLYYFSKFIELLDTIFFVLRK 138

  Fly   137 RYDQVSTLHVIHHGIMPVSVWWGVKFTPGGHSTFFGFLNTFVHIFMYAYYMLAAMGPKVQKYLWW 201
            :..||:.|||.||.|||.:.|:||||..||..||..||||.||:.||:||.|.||||..||||||
Mouse   139 KNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHAFLNTAVHVVMYSYYGLCAMGPAYQKYLWW 203

  Fly   202 KKYLTVMQMIQFVLVMVHSFQLFFKNDCN--YPIGFAYFIGAHAVMFYFLFSNFYKRAYVKRDGK 264
            ||:||.:|::|||||.:|..|:||..|||  ||: |.|.|.::..:|..||.:|:.|||.|....
Mouse   204 KKHLTSLQLVQFVLVTIHIGQIFFMEDCNYQYPV-FLYIIMSYGCIFLLLFLHFWYRAYTKGQRL 267

  Fly   265 DKASVKANGHANGH 278
            .|.....|..:..|
Mouse   268 PKTLENGNCKSKRH 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELOVL	NP_649754.1	ELO	27..266	CDD:366492	132/240 (55%)
Elovl7	NP_083277.3	ELO	30..269	CDD:279492	132/239 (55%)
Elovl7	NP_083277.3	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03207	277..281		0/3 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837635
Domainoid	1	1.000	275	1.000	Domainoid score	I1738
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23672
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2754
Isobase	1	0.950	-	0	Normalized mean entropy	S2719
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		mtm8792
orthoMCL	1	0.900	-	-		OOG6_100254
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740