DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELOVL and CG6660

DIOPT Version :9

Sequence 1:	NP_649754.1	Gene:	ELOVL / 40943	FlyBaseID:	FBgn0037534	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_651104.1	Gene:	CG6660 / 42708	FlyBaseID:	FBgn0039030	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	99/265 - (37%)
Similarity:	146/265 - (55%)	Gaps:	10/265 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RDLMDNKSDPRTRDYPLMSSPFPTIAISLTYAYIVKVLGPKLMENRKPFELRKVLIVYNAAQVIF 76
            |||.....|||....||:.:.:..:||...|...|...||:.|.||.||||::|:.|||..||:.
  Fly    10 RDLYAEHGDPRVAHLPLLGNLWIVLAIVALYVAFVLHYGPRWMANRAPFELKRVMQVYNVVQVLA 74

  Fly    77 SAWLFYESCIGGWLN-GYNLRCEPVNYS-YSPKAIRTAEGCWWYYFSKFTEFFDTFFFVMRKRYD 139
            :|.:|.......:|. ||:..|:||::: .||..::|....:.||..|:.:..||.|.|:||:..
  Fly    75 NATIFVIGLSNTYLQPGYSWTCQPVDHTDRSPAMMKTLYASYAYYMLKYLDLLDTVFIVLRKKNS 139

  Fly   140 QVSTLHVIHHGIMPVSVWWGVKFTPGGHSTFFGFLNTFVHIFMYAYYMLAAMGPKVQKYLWWKKY 204
            |||.|||.|||.|...|...:.|..|.|.:..|.:|..||..|||||..|::| .|:..||||:.
  Fly   140 QVSFLHVYHHGGMVFGVSIFMTFLGGSHCSMLGIINLLVHTVMYAYYYAASLG-AVKNLLWWKQR 203

  Fly   205 LTVMQMIQFVLVMVHSFQLFFKNDCNYPIGFAYFIGAHAVMFYF-LFSNFYKRAYVKRDGKD--- 265
            :|.:|::||..:..|...:..:|.|.:|: |..|||....:|.| :|.:||.:.|:::..|.
  Fly   204 ITQLQLMQFGYLTFHFLLVIVRNPCQFPV-FIAFIGFIQNIFMFSMFFDFYCKTYIRKQRKSAEH 267

  Fly   266 --KAS 268
              |||
  Fly   268 KLKAS 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELOVL	NP_649754.1	ELO	27..266	CDD:366492	90/246 (37%)
CG6660	NP_651104.1	ELO	25..265	CDD:279492	90/241 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449641
Domainoid	1	1.000	108	1.000	Domainoid score	I1638
eggNOG	1	0.900	-	-		E1_KOG3071
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2130
Isobase	1	0.950	-	0	Normalized mean entropy	S2719
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		otm3414
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
	12	11.880