DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELOVL and eloF

DIOPT Version :9

Sequence 1:	NP_649754.1	Gene:	ELOVL / 40943	FlyBaseID:	FBgn0037534	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_649956.1	Gene:	eloF / 41211	FlyBaseID:	FBgn0037762	Length:	257	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	90/276 - (32%)
Similarity:	137/276 - (49%)	Gaps:	59/276 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PLMSSPFPTIAISLTYAYIVKVLGPKLMENRKPFELRKVLIVYNAAQVIFSA--------WLFYE 83
            |::|:|:.|:...:.|...|..||||:||:||||.|..|:.:||..|::::.        :||.
  Fly    11 PVVSNPWITMGTLIGYLLFVLKLGPKIMEHRKPFHLNGVIRIYNIFQILYNGLILVLGVHFLFV- 74

  Fly    84 SCIGGWLNGYNLRC---EPVNYSYSPKAIRTAEGCWWYYFSKFTEFFDTFFFVMRKRYDQVSTLH 145
                  |..|.:.|   .|:::.|..   |....|..|..:||.:..:|.|||:||:..|:|.||
  Fly    75 ------LKAYQISCIVSLPMDHKYKD---RERLICTLYLVNKFVDLVETIFFVLRKKDRQISFLH 130

  Fly   146 VIHHGIMPVSVWWGVKFTPGGHSTFFGF-----------------LNTFVHIFMYAYYMLAAMGP 193
            |.||..|                .|||:                 |||.||:.|||||.|:::..
  Fly   131 VFHHFAM----------------AFFGYLYYCFHGYGGVAFPQCLLNTAVHVIMYAYYYLSSISK 179

  Fly   194 KVQKYLWWKKYLTVMQMIQFVLVMVHSFQLFFKNDC--NYPIGFAYFIGAHAVMFYFLFSNFYKR 256
            :||:.||||||:|:.|::||.::::|......:.:|  |.|:  .|..|:.:..|..:||.||..
  Fly   180 EVQRSLWWKKYITIAQLVQFAIILLHCTITLAQPNCAVNRPL--TYGCGSLSAFFAVIFSQFYYH 242

  Fly   257 AYVKRDGKDKASVKAN 272
            .|:| .||..|....|
  Fly   243 NYIK-PGKKSAKQNKN 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELOVL	NP_649754.1	ELO	27..266	CDD:366492	88/268 (33%)
eloF	NP_649956.1	ELO	11..252	CDD:279492	88/269 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449653
Domainoid	1	1.000	108	1.000	Domainoid score	I1638
eggNOG	1	0.900	-	-		E1_KOG3071
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I1568
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		otm3414
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
	11	10.930