Protein Alignment CD98hc and slc3a2a

DIOPT Version :9

• Sequence 1: NP_001262354.2
• Gene: CD98hc / 40941
• FlyBaseID: FBgn0037533
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_571676.2
• Gene: slc3a2a / 796322
• ZFINID: ZDB-GENE-000831-3
• Length: 485
• Species: Danio rerio
• Alignment Length: 613
• Identity: 130/613 - (21%)
• Similarity: 210/613 - (34%)
• Gaps: 217/613 - (35%)

  Fly    94 RRDEVKFIK-----------------GDHQNGDAKIDIGTVNGGKPAFTGMSKEELMKYANDPFW 141
            :.||:|.::                 |..:||..|:.:  ....:..|||:|||||||.|....|
Zfish     3 KEDEMKEVELNEMDQEKQPMTGETPTGTEKNGSVKVKV--PEDAEVKFTGLSKEELMKVAGTAGW 65

  Fly   142 VRLRWIFFVCFWAIWVGMLVGAILIIIGAPKCAAPQPLP---WYKRGPHAKFASVETCRPEDVQ- 202
            ||.||...|.||..|||||.|||:||:.||:|   :|:|   |:..||..:.::::......::
Zfish    66 VRTRWALLVLFWLGWVGMLAGAIVIIVQAPRC---KPIPEMHWWNEGPLYQISNLDAFSKNGLKG 127

  Fly   203 VAKKL----------VSAGAIYELPA----ALTYDVKKPEV--EEKIKHLVALYQGSDTRVILDL 251
            |.:||          :..|.::.:.|    ||......|:.  |.::..|:.........::|||
Zfish   128 VEEKLDYLSQMKVKGLVLGPVHSVQADQSSALELTSINPDFGSESELTSLLDRAHRKGISIVLDL 192

  Fly   252 TPNYAAKNSQLVQDA-IANPEKRSAFVWVSGGKALPNNWLKVGGNRSAWEKVGDNYVLSQFEDGY 315
            ||||...:|.....| :|...|::...|::.|                             .||
Zfish   193 TPNYRGVSSWFNNAASVAEKLKKACVYWLNKG-----------------------------VDG- 227

  Fly   316 YDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKNTKFFALFDSLEDEQISSSPKDFSLGPNEYGFY 380
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   381 SHRQTTFLSGLGDVLYDY----LSIVKNASD----EAFFSVAEDVMEPQVYQLSGDSGAYGIDLP 437
                 .|||.|.|::..|    :..:.|.:|    :|....|..:...:...|...|   |:||
Zfish   228 -----IFLSDLNDIVNTYAWSSIQAIFNKTDGTPKKALMGTASSLSVDETSLLLNQS---GVDL- 283

  Fly   438 MYGNFVKVLSKSKPDTSL---QKELDNTLAQSGTDSWLQWNLADVYVD----TPQDPSAL-AMFL 494
                   :|:|......|   |..|...|.....::.|.|.|......    ||..|..| ...|
Zfish   284 -------LLTKLPYPAGLSGRQATLMQRLCSGHQEASLGWGLGQTAGSQASRTPALPVKLYQTLL 341

  Fly   495 SLLPGVPV--------VAVDAVAYQNVTEETYRQITSLR-----------KTASYMHGN-LNLYQ 539
            ..|||.||        :......:::|......:.|::|           |..|.:||. :||:.
Zfish   342 FALPGTPVFSAGDELGLKAGEAMWEDVNSTAEEERTAVRNFFKTLSDLKGKERSLLHGEYVNLHN 406

  Fly   540 ADPLVAFSRIKSGNPGYFVIFN---------PTELPQASNFTIPDNLPDKMTVSYFSEQYNNNMD 595
            :...:||.|:...:..:.|..|         ||.          |:||.:..|...::
Zfish   407 SPTSLAFLRLWDQSERFMVAVNWGNDSISMTPTN----------DDLPAEARVRATTD------- 454

  Fly   596 NSGKVAHAGRVNLKDLKVAPHSSIILTY 623
             ..|:|...:|.|:.|::....:::|:|
Zfish   455 -IEKLAVDSKVKLEKLELGSKQAVLLSY 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	116/541 (21%)
slc3a2a	NP_571676.2	SLC3A2_N	42..111	CDD:292647	36/71 (51%)
		AmyAc_SLC3A2	94..396	CDD:200483	71/415 (17%)
		AmyA	125..445	CDD:223443	77/440 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8441
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	1	1.000	-	-		FOG0004629
OrthoInspector	1	1.000	-	-		otm25025
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4341
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.780