Protein Alignment CD98hc and slc3a1

DIOPT Version :9

• Sequence 1: NP_001262354.2
• Gene: CD98hc / 40941
• FlyBaseID: FBgn0037533
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001072903.1
• Gene: slc3a1 / 780365
• XenbaseID: XB-GENE-999160
• Length: 693
• Species: Xenopus tropicalis
• Alignment Length: 741
• Identity: 157/741 - (21%)
• Similarity: 248/741 - (33%)
• Gaps: 262/741 - (35%)

  Fly    59 NPEKVDMVQDEKAAHA--------DGADEQMLGSNGVEDKLAERRDEVKFIKGDHQNGDAKIDIG 115
            :|..|::.|  ||.|.        ||.:|      |..:|:..||:..   :.|......:||..
 Frog     4 DPNSVELKQ--KAGHENNGFISDHDGKEE------GKPEKVEIRRNSK---EEDTHIYSVRIDEI 57

  Fly   116 TVNGG--KPAFTGMSKEELMKYANDPFWVRLRWIFFVCFWAIWV---GMLVGAILIIIGAPKCAA 175
            ..|..  || :.||.|:.|::::|.|.:...|.|.   ||.|.|   .::...|.||..:|||
 Frog    58 PENAPPLKP-YAGMPKDVLLQFSNQPCYRIAREII---FWLIIVATLAIIAATIAIIAISPKC-- 116

  Fly   176 PQPLPWYKRGPHAKFASVETCRPEDVQVAKKLVSAGAIYEL-PAAL-------TYDVKKPEVEEK 232
               |.|::|.|                          ||:: |.:.       :.|:|  .|:||
 Frog   117 ---LDWWQRSP--------------------------IYQVYPKSFKDSNNDGSGDLK--GVQEK 150

  Fly   233 IKHLVAL----------YQGS----------------------------------DTRVILDLTP 253
            |.|.:.|          |:.|                                  ..::|:||.|
 Frog   151 IDHFIYLDVKNIWVAPFYKSSLKDFNYAVDDHMEVDPTFGTMADFDSMISAMHDKGLKLIIDLIP 215

  Fly   254 NYAAKNSQLVQDAIANPEK-RSAFVW-----VSGGKALPNNWLKVGGNRSAWE--KVGDNYVLSQ 310
            |:.:...:..|.:....:| ...::|     |.|.:..||||:.|.|: ||||  ...:...|.|
 Frog   216 NHTSNKHKWFQLSRNRTDKYTDYYIWHDCAQVGGVRVPPNNWVSVYGD-SAWEYDVTRNQCYLHQ 279

  Fly   311 FEDGYYDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKNTKFFALFDSLEDE-QIS--SSPKDFSL 372
            |.....||..|:..:..|...::|..:..||.||.:.:.||....:...|| |::  ..|...|
 Frog   280 FRKEQPDLNFNNPDVHEEILNIIKFWLGKGVDGFTINSAKFILEAEHFRDEPQVNKLQDPATIS- 343

  Fly   373 GPNEYGFYSHRQTTFLSGLGDVLYDYLSIVKNASDEAFFSVAEDVMEPQVYQLSG----DSGAYG 433
               .|....|..||...|:.|::.::...:...|           .||..|:..|    |..|..
 Frog   344 ---NYAELFHDYTTTQVGMHDIIRNFRQTINKYS-----------REPGRYRFMGTESNDQPAID 394

  Fly   434 IDLPMYGN-FVK---------VLSKSKPD---TSLQKELDNTLAQSGTDSWLQWNLADVYVDTP- 484
            ..:..||| |::         :|..|:.:   .|:...:|..:....:..|..|     .|..|
 Frog   395 KTMLYYGNSFIQEADFPLNSYLLDLSRTNLNGLSIFSNVDLWMKSMPSGKWPSW-----MVGGPS 454

  Fly   485 ----------QDPSALAMFLSLLPGVPVV------------------------------------ 503
                      |..:.:.|.|..|||.|..
 Frog   455 YSRISSRVGRQYINVMNMLLLTLPGTPTTYYGEELGMEDGSPNVDTDKPEEYNPVEYPEKTPMQW 519

  Fly   504 -----------------------AVDAVAYQNVTEET---YRQITSLRKTASYMHGNLNLYQADP 542
                                   ||:..|.:|....|   ||::.:||.....:|.....|....
 Frog   520 DSSENAGFSGANKTWLSINPDYEAVNVEAQKNEQYSTLNLYRELNNLRNNELPLHRGWLCYTWSD 584

  Fly   543 LVAFSRIK--SG-NPGYFVIFNPTELPQASNFTIPDNLPD-----KMTVSYFSEQYNNNMDNS-- 597
            |..|:.::  .| |..:.::.|   ...||...:...:||     |:.:|         .|.|
 Frog   585 LNVFAYVRELDGLNKVFMMVLN---FGGASTINMRQEVPDLPAEAKIRLS---------TDGSRV 637

  Fly   598 GKVAHAGRVNLKDLKVAPHSSIILTY 623
            ||..:.|.:..|     |...:||.|
 Frog   638 GKAVNTGSIETK-----PGEGLILEY 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	131/641 (20%)
slc3a1	NP_001072903.1	AmyAc_SLC3A1	118..577	CDD:200494	97/507 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010