Protein Alignment CD98hc and Slc3a2

DIOPT Version :9

• Sequence 1: NP_001262354.2
• Gene: CD98hc / 40941
• FlyBaseID: FBgn0037533
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_062156.2
• Gene: Slc3a2 / 50567
• RGDID: 3073
• Length: 566
• Species: Rattus norvegicus
• Alignment Length: 714
• Identity: 155/714 - (21%)
• Similarity: 246/714 - (34%)
• Gaps: 263/714 - (36%)

  Fly    11 GGGASKSSVTLPAPGVCDSTINAAAEYPPDSTEVYKTIAEDTFVAASS------NPEKVDMVQDE 69
            |||:..........|:....::||.    ||    .|:::||.|....      .|||    |..
  Rat    11 GGGSVPRQPPSAQTGLDVQVVSAAG----DS----GTMSQDTEVDMKDVELNELEPEK----QPM 63

  Fly    70 KAAHADGADEQMLGSNG-VEDKLAERRDEVKFIKGDHQNGDAKIDIGTVNGGKPAFTGMSKEELM 133
            .||....|.|:    || |:.|:||...|.                    |.|  |||:|||||:
  Rat    64 NAADGAAAGEK----NGLVKIKVAEDEAEA--------------------GVK--FTGLSKEELL 102

  Fly   134 KYANDPFWVRLRWIFFVCFWAIWVGMLVGAILIIIGAPKCAAPQPLP---WYKRGPHAKFASVET 195
            |.|..|.|||.||...:.||..|:|||.||::||:.||:|   :.||   |:.:|...:...::.
  Rat   103 KVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRC---RELPVQRWWHKGALYRIGDLQA 164

  Fly   196 -CRPEDVQVAKKLVSAGAIYELPAALTYDVK-----------KPEV--------------EEKIK 234
             ..||    |:.:  ||....|....|..||           |.||              :|..|
  Rat   165 FVGPE----ARGI--AGLKNHLEYLSTLKVKGLVLGPIHKNQKDEVNETDLKQIDPDLGSQEDFK 223

  Fly   235 HLVALYQGSDTRVILDLTPNYAAKNSQLV---QDAIANPEKRSAFVWVSGGKALPNNWLKVGGNR 296
            .|:...:.....:||||||||..:|:..:   .|.:|...|.:...|:..
  Rat   224 DLLQSAKKKSIHIILDLTPNYKGQNAWFLPPQADIVATKMKEALSSWLQD--------------- 273

  Fly   297 SAWEKVGDNYVLSQFEDGYYDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKNTKFFALFDSLEDE 361
                                                       ||.||::
  Rat   274 -------------------------------------------GVDGFQV--------------- 280

  Fly   362 QISSSPKDFSLGPNEYGFYSHRQTTFLSGLGDVLYDYLSIVKNASDEAFF--SVAEDVMEPQVYQ 424
                                 |....|:.....|.::.:|.||.|::...  ..|...::..|..
  Rat   281 ---------------------RDVGKLANASLYLAEWQNITKNFSEDRLLIAGTASSDLQQIVNI 324

  Fly   425 LSGDSGAYGIDLPMYGNFVK--VLSKSKPDTSLQKELDNTLAQSGTDSWLQWNLADVYVDTPQDP 487
            |...|     ||.:..:::.  |.:....:..:.|.|:.|.::     |..|:::...:.|...|
  Rat   325 LESTS-----DLLLTSSYLSQPVFTGEHAELLVIKYLNATGSR-----WCSWSVSQAGLLTSFIP 379

  Fly   488 SALAMFLSL-------LPGVPV------VAVDAVAYQ-------------------------NVT 514
               |.||.|       |||.||      :.:.|||..                         |:|
  Rat   380 ---AQFLRLYQLLLFTLPGTPVFSYGDELGLQAVALPGQPMEAPFMLWNESSNSQTSSPVSLNMT 441

  Fly   515 EE-----------TYRQITSLR-KTASYMHGNLN-LYQADPLVAFSRIKSGNPGYFVIFNPTEL- 565
            .:           .:|:::.|| |..|.:||:.: |..:..|.::.|....|..|.|:.|..::
  Rat   442 VKGQNEDPGSLLTQFRRLSDLRGKERSLLHGDFDALSSSSGLFSYVRHWDQNERYLVVLNFQDVG 506

  Fly   566 ----PQASNFTIPDNLP--DKMTVSYFSEQYNNNMDNSGKVAHAGRVNLKDLKVAPHSSIILTY 623
                ..|||.....:||  ..:.:|..|.:.:.....|        ::|::|.:.|:..::|.:
  Rat   507 LSARVGASNLPAGISLPASANLLLSTDSTRLSREEGTS--------LSLENLSLNPYEGLLLQF 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	123/569 (22%)
Slc3a2	NP_062156.2	SLC3A2_N	85..156	CDD:292647	36/95 (38%)
		AmyAc_family	139..469	CDD:298606	78/445 (18%)
		AmyA	159..514	CDD:223443	81/467 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I8856
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	1	1.000	-	-		FOG0004629
OrthoInspector	1	1.000	-	-		oto95652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4341
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.780