Protein Alignment CD98hc and Mal-A4

DIOPT Version :10

• Sequence 1: NP_001262354.2
• Gene: CD98hc / 40941
• FlyBaseID: FBgn0037533
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_610381.1
• Gene: Mal-A4 / 35827
• FlyBaseID: FBgn0033294
• Length: 579
• Species: Drosophila melanogaster
• Alignment Length: 602
• Identity: 121/602 - (20%)
• Similarity: 215/602 - (35%)
• Gaps: 177/602 - (29%)

  Fly   163 AILIIIGAPKCAAPQPLPWYKRGPHAKFASVETCRPEDVQ---------VAKKL-----VSAGAI 213
            ::.:::|....|.....||:|.   |.|..:.....:|..         |.:||     :...|.
  Fly     6 SLFLLLGLGLLAVDAAAPWWKT---ASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIGVTAT 67

  Fly   214 YELP------AALTYDVKKPE-------VEEKIKHLVALYQGSDTRVILDLTPNYAAKNSQ-LVQ 264
            :..|      |...||:...:       ..|..:::|:..:....::|||..||:::.... .::
  Fly    68 WLSPFLKSPMADFGYDISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECDWFLR 132

  Fly   265 DAIANPEKRSAFVW------VSGGKALPNNWLKV-GGNRSAWEKVGDNYVLSQFEDGYYDLKMNS 322
            .|....|.:..::|      ..|.:..|.||:.| .|:...|.:....|.|.||.....|....:
  Fly   133 SAAGEEEYKDYYMWHPGFLDEDGTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQPDFNFRN 197

  Fly   323 TIIRNEFGAVLKHLVALGVRGFRLKNTKFFALFDSLEDE-----QISSSPK-DFSLGPNEYGFYS 381
            .::|.|...||:..:..||.|||:.     |::.:.|.|     .....|: |::..|:||| |:
  Fly   198 PVVREEMNNVLRFWLEKGVDGFRVD-----AIYHAFEIEADENGNYPDEPRNDWTNDPDEYG-YT 256

  Fly   382 HR-------QTTFLSGLGDVLYDYLSIVK-----NASDEAFFSV-----------------AEDV 417
            |:       :|..|      :|::..|::     |..||....|                 |:..
  Fly   257 HKIYTVDQPETPHL------VYEWRQILEQFQADNGGDERILMVETWSPIEIVMHYYGNETADGA 315

  Fly   418 MEPQVYQLSG----DSGAYGIDLPMYGNFVKVLSKSK---------------------------- 450
            ..|..:||..    ||.||..:. :..|::.::.:.|
  Fly   316 QIPFNFQLISNLHYDSDAYHYEY-LINNWLNLMPEGKSANWVIGNHDKNRVGSRFGADRVDLFNI 379

  Fly   451 -----PDTSLQKELDNTLAQSGTDSWLQWNLADV------------YVDTPQDPSALAMFLS--- 495
                 |..|:..:.:......|..||     .|.            |:|..:||:...|..|
  Fly   380 LLLTLPGCSITYQGEELGMLDGYVSW-----EDTVDPQACNGYEANYMDNSRDPARTPMHWSDET 439

  Fly   496 ----------LLPGVPVVAVDAVAYQNVTEE---------TYRQITSLRKTASYMHGNLNLYQ-A 540
                      .||    |:.| ...:||..|         .::::..||:..|...|:..:.. :
  Fly   440 MAGFTTGNSTWLP----VSTD-YRQRNVKTERGVSLSHLNVFKRLQQLRQEPSIEEGSAEVKAVS 499

  Fly   541 DPLVAFSRIKSGNPGYFVIFNPTELPQASNF-TIPDNLPDKMTVSYFSEQYNNNMDNSGKVAHAG 604
            :.::|..|..||:..|..:||..:..:..|. ::..:||.|...:..:|:   ::...|....||
  Fly   500 NYVLAVKRHLSGDFVYISLFNIFDSIENVNLSSVFGSLPAKFQYALVTEK---SIKKVGDQVSAG 561

  Fly   605 RVNLKDLKVAPHSSIIL 621
            .|.|     .||.||:|
  Fly   562 SVTL-----MPHESIVL 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	111/572 (19%)
Mal-A4	NP_610381.1	AmyAc_maltase	24..492	CDD:200467	95/493 (19%)