DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CD98hc and Mal-A1

DIOPT Version :9

Sequence 1:	NP_001262354.2	Gene:	CD98hc / 40941	FlyBaseID:	FBgn0037533	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_476627.3	Gene:	Mal-A1 / 35824	FlyBaseID:	FBgn0002570	Length:	577	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	105/493 - (21%)
Similarity:	187/493 - (37%)	Gaps:	152/493 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 EDVQVAKKLVSAGA----IYELPAA-LTYDVK-----KPE--VEEKIKHLVALYQGSDTRVILDL 251
            |.:|..|.:...|.    |::.|.. ..||:.     .||  ..|..:.::|..:....::|||.
  Fly    52 EKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDF 116

  Fly   252 TPNYAA-KNSQLVQDAIANPEKRSAFVW-------VSGGKALPNNWLKVGGNR----SAWE--KV 302
            .||::: :|....:...::|..:..::|       .:|.:..|:||     |.    ||||  :|
  Fly   117 VPNHSSTENEWFTKSVDSDPVYKDFYIWHDGKINNETGEREPPSNW-----NSEFRYSAWEWNEV 176

  Fly   303 GDNYVLSQFEDGYYDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKNTKF-FAL----FDSLEDEQ 362
            ...|.|.||.....||...:..:.||...|::..:..||.|||:....: |.:    ::...||.
  Fly   177 RQQYYLHQFAIQQADLNYRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEP 241

  Fly   363 ISSSPKDFSLGPNEYGFYSHRQTTFLSGLGDVLYDYLSI-----VKNASD------EAFFSVAED 416
            :::...:.. .|:::.:..|..|..:....|::|.:..:     |:|..|      ||:.|. |:
  Fly   242 LTNDSVNCP-DPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVENGGDKRLLMTEAYTSF-EN 304

  Fly   417 VMEPQVYQLSGDSGAYGIDLP--------------------------------MYGNFV------ 443
            :|   .|.  |:....|..:|                                :|.|:|
  Fly   305 IM---TYY--GNGVRNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPEGVYANWVLGNHDN 364

  Fly   444 -KVLSKSKPDTSLQK-ELDNTLAQS--------------GTDSWLQW----------NLADVYVD 482
             :|.|:    ..:|: :|.|.|.|:              .||.|:.|          :..|.|..
  Fly   365 KRVASR----FGVQRTDLINILLQTLPGHAVTYNGEELGMTDVWISWEDTVDPNACNSDPDNYYA 425

  Fly   483 TPQDP---------SALAMFLSL----LPGVPVVAVDAVAYQNVTE---------ETYRQITSLR 525
            ..:||         |:.|.|.|.    ||     ..|.....|..:         :.::::..:|
  Fly   426 RSRDPARSPYQWDASSKAGFTSADHTWLP-----VADDYKTNNALQQLRAPRSHLQIFKKLVRVR 485

  Fly   526 KTASYMHGNLNLYQA--DPLVAFSRIKSGNPGYFVIFN 561
            |..|:..|.||: ||  |.::.:||.|:|:..|.::.|
  Fly   486 KEPSFRQGELNI-QAIDDDVIIYSRQKTGSDLYVIVLN 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	105/493 (21%)
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	94/464 (20%)
Mal-A1	NP_476627.3	Alpha-amylase	45..404	CDD:278554	76/367 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.820