Protein Alignment CD98hc and Slc3a1

DIOPT Version :9

• Sequence 1: NP_001262354.2
• Gene: CD98hc / 40941
• FlyBaseID: FBgn0037533
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_033231.2
• Gene: Slc3a1 / 20532
• MGIID: 1195264
• Length: 685
• Species: Mus musculus
• Alignment Length: 585
• Identity: 130/585 - (22%)
• Similarity: 216/585 - (36%)
• Gaps: 156/585 - (26%)

  Fly    88 EDKLAERRDEVKF-IKGDHQNG---------DAKIDIGTVNGGKP-----------------AFT 125
            |||  .:||.::. :||...|.         :...|.|:.:..:|                 .:.
Mouse     3 EDK--GKRDPIQMSLKGCRTNNGFVQNEDIPEQDPDPGSRDTPQPNAVSIPAPEEPHLKAVRPYA 65

  Fly   126 GMSKEELMKYANDPFWVRLRWIFFVCFW--AIWVGMLVGA-ILIIIGAPKCAAPQPLPWYKRGP- 186
            ||.||.|.:::..   .|.|....:.||  .:.|.:|:|| |.||:.:|||     |.|::.||
Mouse    66 GMPKEVLFQFSGQ---ARYRVPREILFWLTVVSVFLLIGATIAIIVISPKC-----LDWWQAGPI 122

  Fly   187 ----HAKFASVETCRPEDVQ-VAKKL--VSAGAIYELPAALTY------------DVKKPEVE-- 230
                ...|...:.....|:: :.:||  ::|..|..|.....|            |.|  |::
Mouse   123 YQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFK--EIDPI 185

  Fly   231 ----EKIKHLVALYQGSDTRVILDLTPNYAAKNSQLVQDAIANPEK-RSAFVW-----VSGGKAL 285
                :..::|||.......::|:|..||:.:......|.:.....| ...::|     |:|....
Mouse   186 FGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSRTRSGKYTDYYIWHNCTHVNGVTTP 250

  Fly   286 PNNWLKVGGNRSAW--EKVGDNYVLSQFEDGYYDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKN 348
            |||||.|.|| |:|  ::|.......||.....||...:..::.|...::...::.||.||....
Mouse   251 PNNWLSVYGN-SSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKEIITFWLSKGVDGFSFDA 314

  Fly   349 TKFFALFDSLEDE-QISSSPKDFSLGPNEYGFYS---HRQTTFLSGLGDVLYDYLSIVKNASDE- 408
            .||......|.:| |:::|..     |:....||   |..||...|:.|::.|:...:...|.|
Mouse   315 VKFLLEAKDLRNEIQVNTSQI-----PDTVTHYSELYHDFTTTQVGMHDIVRDFRQTMNQYSREP 374

  Fly   409 ---AFFSV---AEDVMEPQVYQLSGDSGAYGI------DLPMYGNFVKVLSKSKPDTSLQKELDN 461
               .|...   ||.:....:|        ||:      |.|....|..:.:.|  ..::.:.:.:
Mouse   375 GRYRFMGAEASAESIERTMMY--------YGLPFIQEADFPFNKYFTTIGTLS--GHTVYEVITS 429

  Fly   462 TLAQSGTDSWLQWNLADVYVDTPQDP-----------SALAMFLSLLPGVPV------VAVDAVA 509
            .:.......|..|     ....|:.|           :|:.|.|..|||.|:      :.:..::
Mouse   430 WMENMPEGKWPNW-----MTGGPETPRLTSRVGSEYVNAMHMLLFTLPGTPITYYGEEIGMGDIS 489

  Fly   510 YQNVTEETYRQITSLRKTASYMHGNLNLYQADPLVAFSRIK---SGNPGYFVIFNPTELPQASNF 571
            ..|..|.                     |.:..||:.|.::   |.|.| |...|.|.||..|::
Mouse   490 VTNFNES---------------------YDSTTLVSKSPMQWDNSSNAG-FTEANHTWLPTNSDY 532

  Fly   572  571
            Mouse   533  532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	120/546 (22%)
Slc3a1	NP_033231.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		11/51 (22%)
		SLC3A2_N	64..122	CDD:292647	22/65 (34%)
		AmyAc_SLC3A1	115..568	CDD:200494	99/463 (21%)
		trehalose_treC	116..604	CDD:274115	99/462 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810