Protein Alignment CD98hc and Slc3a2

DIOPT Version :9

• Sequence 1: NP_001262354.2
• Gene: CD98hc / 40941
• FlyBaseID: FBgn0037533
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001154885.1
• Gene: Slc3a2 / 17254
• MGIID: 96955
• Length: 565
• Species: Mus musculus
• Alignment Length: 670
• Identity: 153/670 - (22%)
• Similarity: 244/670 - (36%)
• Gaps: 240/670 - (35%)

  Fly    47 TIAEDTFVAASS------NPEKVDMVQDEKAAHADGADEQMLGSNG-VEDKLAERRDEVKFIKGD 104
            |:::||.|....      .|||    |...||....|.|:    || |:.|:||  ||
Mouse    39 TMSQDTEVDMKDVELNELEPEK----QPMNAADGAAAGEK----NGLVKIKVAE--DE------- 86

  Fly   105 HQNGDAKIDIGTVNGGKPAFTGMSKEELMKYANDPFWVRLRWIFFVCFWAIWVGMLVGAILIIIG 169
                       |..|.|  |||:|||||:|.|..|.|||.||...:.||..|:|||.||::||:.
Mouse    87 -----------TEAGVK--FTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVR 138

  Fly   170 APKCAAPQPLP---WYKRGPHAKFASVETCRPEDVQVAKKLVSAGAIYELPAALTY--------- 222
            ||:|   :.||   |:.:|...:...::.....|         ||.|..|.:.|.|
Mouse   139 APRC---RELPVQRWWHKGALYRIGDLQAFVGRD---------AGGIAGLKSHLEYLSTLKVKGL 191

  Fly   223 ----------------DVKK--PEV--EEKIKHLVALYQGSDTRVILDLTPNYAAKNSQLV---Q 264
                            |:|:  |.:  :|..|.|:...:.....:||||||||..:|:..:   .
Mouse   192 VLGPIHKNQKDEINETDLKQINPTLGSQEDFKDLLQSAKKKSIHIILDLTPNYQGQNAWFLPAQA 256

  Fly   265 DAIANPEKRSAFVWVSGGKALPNNWLKVGGNRSAWEKVGDNYVLSQFEDGYYDLKMNSTIIRNEF 329
            |.:|...|.:...|:..|         |.|              .||.|  ....||:.:...|:
Mouse   257 DIVATKMKEALSSWLQDG---------VDG--------------FQFRD--VGKLMNAPLYLAEW 296

  Fly   330 GAVLKH-----LVALGVRGFRLKNTKFFALFDSLEDEQISSSPKDFSLGPNEYGFYSHRQ----T 385
            ..:.|:     |:..|.....|:  :...:.:|..|..::||....|.      |...|.    |
Mouse   297 QNITKNLSEDRLLIAGTESSDLQ--QIVNILESTSDLLLTSSYLSNST------FTGERTESLVT 353

  Fly   386 TFLSGLG---------------DVLYDYLSIVKNASDEAFFSVAEDVMEPQVYQL------SGDS 429
            .||:..|               |.:.|:|.                    ::|||      ....
Mouse   354 RFLNATGSQWCSWSVSQAGLLADFIPDHLL--------------------RLYQLLLFTLPGTPV 398

  Fly   430 GAYGIDLPMYGNFVKVLSKSKPDTSLQKELDNTLAQSGTDSWLQWNLADVY-VDTP--------- 484
            .:||.:|.:.|        :.|....:..|            :.||.:.:: :..|
Mouse   399 FSYGDELGLQG--------ALPGQPAKAPL------------MPWNESSIFHIPRPVSLNMTVKG 443

  Fly   485 --QDPSALAMFLSLLPGVPVVAVDAVAYQNVTEETYRQITSLR-KTASYMHGNLNLYQADP-LVA 545
              :||.:|                      :|:  :|:::.|| |..|.:||:.:...:.| |.:
Mouse   444 QNEDPGSL----------------------LTQ--FRRLSDLRGKERSLLHGDFHALSSSPDLFS 484

  Fly   546 FSRIKSGNPGYFVIFNPTELPQ-----ASNFTIPDNLP--DKMTVSYFSEQYNNNMDNSGKVAHA 603
            :.|....|..|.|:.|..:..:     |||.....:||  .|:.:|..|.:.:...|.|
Mouse   485 YIRHWDQNERYLVVLNFRDSGRSARLGASNLPAGISLPASAKLLLSTDSARQSREEDTS------ 543

  Fly   604 GRVNLKDLKVAPHSSIILTY 623
              :.|::|.:.|:..::|.:
Mouse   544 --LKLENLSLNPYEGLLLQF 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	126/561 (22%)
Slc3a2	NP_001154885.1	SLC3A2_N	85..156	CDD:292647	38/93 (41%)
		AmyAc_family	139..468	CDD:298606	80/437 (18%)
		AmyA	169..513	CDD:223443	83/449 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I9042
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.712175	Normalized mean entropy	S6632
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1384693at2759
OrthoFinder	1	1.000	-	-		FOG0004629
OrthoInspector	1	1.000	-	-		oto92084
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4341
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.730