Protein Alignment dsx and DMRT3

DIOPT Version :9

• Sequence 1: NP_001262353.1
• Gene: dsx / 40940
• FlyBaseID: FBgn0000504
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_067063.1
• Gene: DMRT3 / 58524
• HGNCID: 13909
• Length: 472
• Species: Homo sapiens
• Alignment Length: 530
• Identity: 131/530 - (24%)
• Similarity: 187/530 - (35%)
• Gaps: 154/530 - (29%)

  Fly    33 GSSIS--PRTP----PNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMALQTALRR 91
            |..:|  ||.|    |.||||||||:...||||||||:|:.||||||.|..:||||||.|.||||
Human    12 GGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRR 76

  Fly    92 AQAQDEQRAL---HMHEVPPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHHSHHGHVLHH 153
            .||.:...:|   .:..:|...|....       ||||                         ..
Human    77 QQANESLESLIPDSLRALPGPPPPGDA-------VAAP-------------------------QP 109

  Fly   154 QQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQHQSHPHSHHHHHQN 218
            ..|:..:...|..||:.|    .||:::...|......:.|..|......:......|
Human   110 PPASQPSQPQPPRPAAEL----AAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKS------- 163

  Fly   219 HHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGGAPSSSNAAAATSSNGSSGGGGGGGGGSS 283
                     |..|.:.|...:|...|...| .|.|...|.|....:...         ||.....
Human   164 ---------ADNTEVFSDKDTDQRSSPDVA-KSKGCFTPESPEIVSVEE---------GGYAVQK 209

  Fly   284 GGGAGGGRSSGTSVITSADHHMTTVPTPAQSLEGSCDSSSPSPSSTSGAAILPISVSVNRKNGAN 348
            .||....|..........:|.:         :||           .||...||.|:..||.
Human   210 NGGNPESRPDSPKCHAEQNHLL---------IEG-----------PSGTVSLPFSLKANRP---- 250

  Fly   349 VPLGQDVFLDYCQKLLEKFRYPWELMPLMYVILKDADANIEEASRRIEEARVEI---NRTVAQIY 410
             ||          ::|:|. :|.:...::.:|||....::..|...:..:|..:   .||.|:
Human   251 -PL----------EVLKKI-FPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAE-- 301

  Fly   411 YNYYTP--MALVNGAPMY----LTYP-SIEQGRYGAHFTHLPLTQICPPT-----------PEPL 457
                 |  :||.:...::    .:|| |..:...|:.|.       .|.|           |.||
Human   302 -----PESLALPSNGHIFEHTLSSYPISSSKWSVGSAFR-------VPDTLRFSADSSNVVPSPL 354

  Fly   458 ALSRSPSSPSGPSAVHNQKPSRPGSSNGTVHSAASPTMVTTMATTSSTPTLSRRQRSRSATPTTP 522
            |   .|..|..|     |.|..|.....|:..:.|...:....|..:|.||.::.:.||...:
Human   355 A---GPLQPPFP-----QPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVS-- 409

  Fly   523 PPPPPAHSSS 532
              |.|::|:|
Human   410 --PFPSNSTS 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	32/48 (67%)
		DSX_dimer	353..404	CDD:285978	8/53 (15%)
DMRT3	NP_067063.1	DM	25..71	CDD:279137	31/45 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..128		11/74 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..191		9/52 (17%)
		CUE_DMA_DMRTA3	247..289	CDD:270602	11/57 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	430..472

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383821at33208
OrthoFinder	1	1.000	-	-		FOG0006418
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820