DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsx and Dmrt1

DIOPT Version :9

Sequence 1:	NP_001262353.1	Gene:	dsx / 40940	FlyBaseID:	FBgn0000504	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_030106845.1	Gene:	Dmrt1 / 50796	MGIID:	1354733	Length:	475	Species:	Mus musculus

Alignment Length:	239	Identity:	78/239 - (32%)
Similarity:	107/239 - (44%)	Gaps:	46/239 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GGASSS------SGSSISPRTPPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMA 84
            ||||.|      |||..|||. |.||||||||....||||||:|.:|.|.|:||.|.|:||||||
Mouse    51 GGASGSGPSGLGSGSKKSPRL-PKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMA 114

  Fly    85 LQTALRRAQAQDEQRALHMHEVP-PANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHHSHHG 148
            .|.||||.|||:|:..: .|.:| |:  ||..|:...::.:.|..:..:...|
Mouse   115 AQVALRRQQAQEEELGI-SHPIPLPS--AAELLVKRENNASNPCLMAENSSSA------------ 164

  Fly   149 HVLHHQQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQHQSHPHSHH 213
                  |...|:...|:|....:......|.:..|     |:...:...:..|.:.....| |..
Mouse   165 ------QPPPASTPTPAASEGRMVIQDIPAVTSRG-----HMENTSDLVSDPAYYSSFYQP-SLF 217

  Fly   214 HHHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGGAP 257
            .::.|.:.:|....|......|       |.||    :|.||:|
Mouse   218 PYYNNLYNYPQYSMALSAESSS-------GEVG----NSLGGSP 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	29/44 (66%)
dsx	NP_001262353.1	DSX_dimer	353..404	CDD:285978
Dmrt1	XP_030106845.1	DM	70..116	CDD:366283	30/46 (65%)
Dmrt1	XP_030106845.1	Dmrt1	128..200	CDD:372081	15/97 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6174
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12322
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4813
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950