DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsx and dmrt99B

DIOPT Version :9

Sequence 1:	NP_001262353.1	Gene:	dsx / 40940	FlyBaseID:	FBgn0000504	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_524549.1	Gene:	dmrt99B / 43495	FlyBaseID:	FBgn0039683	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	107/372 - (28%)
Similarity:	135/372 - (36%)	Gaps:	105/372 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DSDMIDSKNDVCGGASSS----SGSSISPRTPPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCR 74
            |...:.|::.|.|....:    :.|....|| |.||||||||:...||||||||::|.|.|.||.
  Fly     8 DMQNLMSQHPVLGALPPAFFLRAASERYQRT-PKCARCRNHGVVSALKGHKRYCRWRDCVCAKCT 71

  Fly    75 LTADRQRVMALQTALRRAQAQDEQRALHMHEVPPANPAATTLLSHHHHVAAPAHVHAHHVHAHHA 139
            |.|:||||||.|.||||.|||:|..|..:           .||    :.:.|.
  Fly    72 LIAERQRVMAAQVALRRQQAQEENEAREL-----------GLL----YTSVPG------------ 109

  Fly   140 HGGHHSHHGHVLHHQQAAAAAAAAPSAP-ASHLGGSSTAASSIHG--HAHAHHVHMAAAAAASVA 201
                         .|..:.:|...|.:| .|..|||.:..|..:|  |............|:|..
  Fly   110 -------------QQNGSDSATPTPHSPNHSGSGGSGSGGSGQNGVFHGGIPSPPSDGFEASSTP 161

  Fly   202 QHQHQSHPHSHHHHHQNHHQHPHQQ------------------------PATQTALRSPPHSDHG 242
            .| ||........|||.|..|||||                        ..|:|.|...|.|..|
  Fly   162 NH-HQQSQQQQQAHHQQHLSHPHQQSQRFNGNESDTDGRTRSEHLSVGFSPTRTELDESPVSKRG 225

  Fly   243 GSVGPATSSSGG---GAPSSSNAAAATSSNGSSGGGGGGGGGSSGGGAGGGRSSGTSVITSADHH 304
            .::...|....|   |:|||.....|...|.::         |......|..||..|     |..
  Fly   226 AALSNETDQDTGSESGSPSSPRPKVAGLFNLTA---------SLSPARTGPPSSPES-----DLD 276

  Fly   305 MTTVP---TPAQSLEGSCDSSSP------------SPSSTSGAAILP 336
            :.:.|   ||........||.||            |.||:.....||
  Fly   277 VDSAPDEATPENLSLKKEDSQSPPNTPAENLHLLRSFSSSHAQGFLP 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	30/44 (68%)
dsx	NP_001262353.1	DSX_dimer	353..404	CDD:285978
dmrt99B	NP_524549.1	DM	37..83	CDD:279137	32/46 (70%)
dmrt99B	NP_524549.1	CUE_DMA_DMRTA1	378..415	CDD:270600
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12322
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000