DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsx and Dmrta1

DIOPT Version :9

Sequence 1:	NP_001262353.1	Gene:	dsx / 40940	FlyBaseID:	FBgn0000504	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001101415.1	Gene:	Dmrta1 / 313352	RGDID:	1309796	Length:	488	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	88/280 - (31%)
Similarity:	110/280 - (39%)	Gaps:	60/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PRTPPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMALQTALRRAQAQDEQRALH 102
            ||| |.||||||||:...||||||:|::|.|.|.||.|.|:||||||.|.||||.|||:|..|..
  Rat    79 PRT-PKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARG 142

  Fly   103 MHEV---PPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHHSHHGHVLHHQQAAAAAAAAP 164
            :|.:   .|:.|            .|||           :.|...:....||......||..|..
  Rat   143 LHRLLYQGPSGP------------GAPA-----------SGGSGRTESPQVLSSPMTVAALGAGA 184

  Fly   165 SAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQHQSHPHSHHHHHQNHHQHPHQQPAT 229
            |   .|.|..|..|..:.....|..           .|...||:..|        .|..|::|.:
  Rat   185 S---RHPGSRSVPAFEVFQQDFAER-----------KQEPKQSNCES--------CQSRHEEPVS 227

  Fly   230 QTALRSPPHSDHGGSVGPATSSSGGGAPSSSNAAAATS------SNGSSGGGGGGGGGSSGGGAG 288
            .|..|||     |.|.|..|....|...|.|..:..::      ....|||.......||.....
  Rat   228 NTHHRSP-----GSSNGNVTMEKQGFMSSISEQSDKSTIILSPCPTDQSGGEDSPRSFSSSDLES 287

  Fly   289 GGRSSGTSVITSADHHMTTV 308
            |..|......|:....::||
  Rat   288 GNESEWARDYTATTASLSTV 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	29/44 (66%)
dsx	NP_001262353.1	DSX_dimer	353..404	CDD:285978
Dmrta1	NP_001101415.1	DM	80..126	CDD:279137	31/46 (67%)
Dmrta1	NP_001101415.1	DMA	313..348	CDD:281472
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900