Protein Alignment dsx and Dmrt3

DIOPT Version :9

• Sequence 1: NP_001262353.1
• Gene: dsx / 40940
• FlyBaseID: FBgn0000504
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001099828.1
• Gene: Dmrt3 / 293976
• RGDID: 1306043
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 134/554 - (24%)
• Similarity: 190/554 - (34%)
• Gaps: 198/554 - (35%)

  Fly    33 GSSIS--PRTP----PNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMALQTALRR 91
            |..:|  ||.|    |.||||||||:...||||||||:|:.||||||.|..:||||||.|.||||
  Rat    12 GGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRR 76

  Fly    92 AQAQDEQRALHMHEV-------PPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHHSHHGH 149
            .||.:...:|....:       ||.:.|||...:..   ::||
  Rat    77 QQANESLESLIPDSLRALPGPPPPGDAAATAATASQ---SSPA---------------------- 116

  Fly   150 VLHHQQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQHQSHPHSHHH 214
                  :.|:...||..||:.|.                    ||||...||:
  Rat   117 ------SQASQPPAPPRPATELA--------------------AAAALRWVAE------------ 143

  Fly   215 HHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGGAPSSSNAAAATSSNGSSGGGGGGG 279
                      .||.|..|..:.|         ..|....|.:.|:.|||.:.|...:.
  Rat   144 ----------PQPGTLPAQIAKP---------DLTEDRLGDSSSADNAAESFSDKDTD------- 182

  Fly   280 GGSSGGGAGGGRSSGTSVITSADHHMTTVPT---------PAQSLEGSCDSSSPSP--------- 326
                       :.|...|:.|.:......|.         ..|...|:.:|...||
  Rat   183 -----------QRSSPDVVKSKNCFTPESPEIVSVDEGGYAVQKNGGNPESCPDSPKYHAEQSHL 236

  Fly   327 --SSTSGAAILPISVSVNRKNGANVPLGQDVFLDYCQKLLEKFRYPWELMPLMYVILKDADANIE 389
              ...||...||.|:..||.     ||          ::|:|. :|.:...::.:|||....::.
  Rat   237 LIEGPSGTVSLPFSLKANRP-----PL----------EVLKKI-FPNQKPTVLELILKGCGGDLV 285

  Fly   390 EA-----SRRIEEARVEINRTVAQIYYNYYTPMALVNGAPMYL----TYP-SIEQGRYGAHFTHL 444
            .|     |.|...|..|  ||..:       .:.|.:...::.    :|| |..:...|:.|.
  Rat   286 SAVEVLLSSRSSAAGAE--RTAEE-------SLVLPSSGHIFEHTLGSYPISSSKWSVGSAFR-- 339

  Fly   445 PLTQICPPT-----------PEPLALSRSPSSPSGPSAVHNQKPSRPGSSNGTVHSAASPTMVTT 498
                 .|.|           |.|||:......|        |.|..|.....|:....|...:..
  Rat   340 -----VPDTLRFSADSSNVVPNPLAVPLQHPFP--------QPPRYPLMLRNTLARNQSSPFLPN 391

  Fly   499 MATTSSTPTLSRRQRSRSATPTTPPPPPPAHSSS 532
            ..|..:|.||.::.:.||...:    |.|::|:|
  Rat   392 DVTLWNTMTLQQQYQLRSQYVS----PFPSNSTS 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	32/48 (67%)
		DSX_dimer	353..404	CDD:285978	11/55 (20%)
Dmrt3	NP_001099828.1	DM	25..71	CDD:395608	31/45 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..130		11/71 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..195		13/74 (18%)
		CUE_DMA_DMRTA3	253..295	CDD:270602	12/57 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..476		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383821at33208
OrthoFinder	1	1.000	-	-		FOG0006418
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820