Protein Alignment dsx and Dmrt3

DIOPT Version :9

• Sequence 1: NP_001262353.1
• Gene: dsx / 40940
• FlyBaseID: FBgn0000504
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_796334.2
• Gene: Dmrt3 / 240590
• MGIID: 2449470
• Length: 476
• Species: Mus musculus
• Alignment Length: 555
• Identity: 138/555 - (24%)
• Similarity: 191/555 - (34%)
• Gaps: 200/555 - (36%)

  Fly    33 GSSIS--PRTP----PNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMALQTALRR 91
            |..:|  ||.|    |.||||||||:...||||||||:|:.||||||.|..:||||||.|.||||
Mouse    12 GGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRR 76

  Fly    92 AQAQDEQRALHMHEV-------PPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHHSHHGH 149
            .||.:...:|....:       ||.:.|||         ||.|
Mouse    77 QQANESLESLIPDSLRALPGPPPPGDAAAT---------AATA---------------------- 110

  Fly   150 VLHHQQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAAS-VAQHQHQSHPHSHH 213
               .|.:.|:.|:.|.||.     ..||             .:|||||.. ||:
Mouse   111 ---SQSSPASQASQPPAPP-----RPTA-------------ELAAAAALRWVAE----------- 143

  Fly   214 HHHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGGAPSSSNAAAATSSNGSSGGGGGG 278
                       .||.|..|..:.|         ..|....|.:.|:.|.|.|.|...:.
Mouse   144 -----------PQPGTLPAQLAKP---------DLTEERVGDSSSTDNTAEAFSDKDTD------ 182

  Fly   279 GGGSSGGGAGGGRSSGTSVITSADHHMTTVPT---------PAQSLEGSCDSSSPSP-------- 326
                        :.|...|:.|.:......|.         ..|...|:.:|...||
Mouse   183 ------------QRSSPDVVKSKNCFTPESPEIVSVDEGGYAVQKNGGNPESCPDSPKYHAEQSH 235

  Fly   327 ---SSTSGAAILPISVSVNRKNGANVPLGQDVFLDYCQKLLEKFRYPWELMPLMYVILKDADANI 388
               ...||...||.|:..||.     ||          ::|:|. :|.:...::.:|||....::
Mouse   236 LLIEGPSGTVSLPFSLKANRP-----PL----------EVLKKI-FPNQKPTVLELILKGCGGDL 284

  Fly   389 EEA-----SRRIEEARVEINRTVAQIYYNYYTPMALVNGAPMYL----TYP-SIEQGRYGAHFTH 443
            ..|     |.|...|..|  ||..:       .:.|.:...::.    :|| |..:...|:.|.
Mouse   285 VSAVEVLLSSRSSAAGAE--RTAEE-------SLVLPSSGHIFEHTLGSYPISSSKWSVGSAFR- 339

  Fly   444 LPLTQICPPT-----------PEPLALSRSPSSPSGPSAVHNQKPSRPGSSNGTVHSAASPTMVT 497
                  .|.|           |.|||:......|        |.|..|.....|:....|...:.
Mouse   340 ------VPDTLRFSADSSNVVPNPLAVPLQHPFP--------QPPRYPLMLRNTLARNQSSPFLP 390

  Fly   498 TMATTSSTPTLSRRQRSRSATPTTPPPPPPAHSSS 532
            ...|..:|.||.::.:.||...:    |.|::|:|
Mouse   391 NDVTLWNTMTLQQQYQLRSQYVS----PFPSNSTS 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	32/48 (67%)
		DSX_dimer	353..404	CDD:285978	11/55 (20%)
Dmrt3	NP_796334.2	DM	25..71	CDD:366283	31/45 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..130		14/79 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..195		13/74 (18%)
		CUE_DMA_DMRTA3	253..295	CDD:270602	12/57 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..476		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383821at33208
OrthoFinder	1	1.000	-	-		FOG0006418
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820