DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsx and dmd-5

DIOPT Version :9

Sequence 1:	NP_001262353.1	Gene:	dsx / 40940	FlyBaseID:	FBgn0000504	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_495138.2	Gene:	dmd-5 / 184287	WormBaseID:	WBGene00017326	Length:	280	Species:	Caenorhabditis elegans

Alignment Length:	274	Identity:	73/274 - (26%)
Similarity:	106/274 - (38%)	Gaps:	85/274 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SSSGSSISPRT---------------PPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADR 79
            |.|..|:.|.|               .|.||||||||....||||||||:::.|.|.||.|.|:|
Worm     4 SPSSVSVLPPTSLEQILRIRAERNQRTPKCARCRNHGTTSALKGHKRYCQWKDCMCAKCTLIAER 68

  Fly    80 QRVMALQTALRRAQAQDEQRALHMHEVPPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHGGHH 144
            |||||.|.||||.|:|:|:.|..:..:..:...|..||.            ...:.|...||.:|
Worm    69 QRVMAAQVALRRQQSQEERDARDLEVLLGSAGNANDLLD------------ILRLDAGEHHGKNH 121

  Fly   145 -----SHHGHVLHHQQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQ 204
                 :::.:.....:.:....::||:|.    ||.|..|:                 :|..:..
Worm   122 ASPTTNNNNNTEEKYEDSQGQRSSPSSPT----GSETVVST-----------------SSPPELS 165

  Fly   205 HQSHPHSHHHHHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGG--------------- 254
            .:|.|::                :......||....:|.|..|..:...|
Worm   166 SESTPNT----------------SGSVIPTSPVFKPNGYSSMPMFNPVYGRPFMRFPMFSVMPHF 214

  Fly   255 -GAPSSSNAAAATS 267
             |.||.|:.|:|.|
Worm   215 FGTPSMSDFASAAS 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	29/44 (66%)
dsx	NP_001262353.1	DSX_dimer	353..404	CDD:285978
dmd-5	NP_495138.2	DM	29..75	CDD:366283	29/45 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4813
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900