DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsx and dmd-7

DIOPT Version :9

Sequence 1:	NP_001262353.1	Gene:	dsx / 40940	FlyBaseID:	FBgn0000504	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_741551.1	Gene:	dmd-7 / 179012	WormBaseID:	WBGene00019521	Length:	449	Species:	Caenorhabditis elegans

Alignment Length:	363	Identity:	68/363 - (18%)
Similarity:	115/363 - (31%)	Gaps:	111/363 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 CGGASSSSGSSISPRTPPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLTADRQRVMALQ--T 87
            |||||.||..::.      |.:|..||.::.||||...|.|..|:|:.|      ..||:::  .
Worm    48 CGGASRSSNRTLF------CRKCEGHGQQVVLKGHASRCPFNNCSCKTC------TNVMSMRANA 100

  Fly    88 ALRRAQAQDEQRALHMHEVPPANPAATTLLSHHHHVAAPAHVHAHHVHAHHA---HGGHHSHHGH 149
            .:||.:.:..:..|.:..|            |..:......|...::....|   |..:.:.:|
Worm   101 IIRRYRTRTLEGGLVLKPV------------HFKNGNTRLRVFPKNIDERDALTIHFNNKNQNG- 152

  Fly   150 VLHHQQAAAAAAAAPSAPASHLGGSSTAASSIHGHAHAHHVHMAAAAAASVAQHQHQSH-PHSHH 213
             |.:..||.......:.|.     :|..|::|....:|.:..|...:.:.....:...| |....
Worm   153 -LANMNAAEMQMEVGAYPQ-----TSPPATAIPDSGNAQNPFMVKRSQSDQELDRQSGHTPTIVE 211

  Fly   214 HHHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGG-------------APSSSNAAAA 265
            ...|...|.....|......:|||         |...|:..|             .|.:..|...
Worm   212 QARQVQQQFSATNPPNYGLDQSPP---------PMPPSTANGQMPMGILSDFSLLTPETITAIKN 267

  Fly   266 TSSNGSSGGGGGGGGGSSGGGAGGGRSSGTSVITSADHHMTTVPTP------------------- 311
            ..:                       ..|..::|      ||.|||
Worm   268 LFN-----------------------PQGNDIVT------TTAPTPSIFDNTFLSNLNIANGVTY 303

  Fly   312 -AQSLEGSCDSSSPSPSSTSGAAILPISVSVNRK--NG 346
             :.::.|:....:|..::.|...:.|.. .::||  ||
Worm   304 TSANMNGNQMLMTPQVTTASSTGMFPFE-DIDRKLSNG 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	15/44 (34%)
dsx	NP_001262353.1	DSX_dimer	353..404	CDD:285978
dmd-7	NP_741551.1	DM	57..108	CDD:214606	17/62 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12322
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100