DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsx and dmrt1

DIOPT Version :9

Sequence 1:	NP_001262353.1	Gene:	dsx / 40940	FlyBaseID:	FBgn0000504	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_031746577.1	Gene:	dmrt1 / 100488257	XenbaseID:	XB-GENE-852569	Length:	337	Species:	Xenopus tropicalis

Alignment Length:	360	Identity:	100/360 - (27%)
Similarity:	142/360 - (39%)	Gaps:	82/360 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MSDSDMIDSKNDVCGGASSSSGSSISPRTPPNCARCRNHGLKITLKGHKRYCKFRYCTCEKCRLT 76
            |.:::...||....|...|......|||. |.||||||||....||||||:|.:|.|.|:||.|.
Frog     1 MQNNEEPFSKTRSSGQHPSGVHGKKSPRL-PKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLI 64

  Fly    77 ADRQRVMALQTALRRAQAQDEQRALHMHEVPPANPAATTLLSHHHHVAAPAHVHAHHVHAHHAHG 141
            |:||||||.|.||||.|||:|:..: .|.:|  .|.|..||                  ....||
Frog    65 AERQRVMAAQVALRRQQAQEEELGI-SHPIP--LPIAAELL------------------IKREHG 108

  Fly   142 GHHSHHGHVLHHQQAAAAAAAAPSAPASHLGGSSTAAS---------SIHGHAHAHHVHMAAAAA 197
            |..|          .....:::....::...||:|::.         ||....|..      :.:
Frog   109 GSSS----------CLMLESSSTQTTSTSTSGSTTSSEGKMLIQEIPSITSRGHLE------STS 157

  Fly   198 ASVAQHQHQSHPHSH--HHHHQNHHQHPHQQPATQTALRSPPHSDHGGSVGPATSSSGGGAPSSS 260
            ..|....:.|:.:..  :.::.|.:.:|..|.|..|  .|...:|.||..||:..:|....|
Frog   158 DLVMDSPYYSNFYQPPLYPYYNNLYNYPPYQMAVAT--ESTSGNDMGGISGPSMKNSHRNHP--- 217

  Fly   261 NAAAATSSNGSSGGGGGGGGGSSGGGAGG------------GRSSGTSVI-----------TSAD 302
             ||...|.:|:......|.....|..|..            |:|....|.           :.::
Frog   218 -AAYVPSQSGNQWQMKNGENRFPGHSASSQFRMHSYYPPYLGQSVPNPVCVPPFLTFEEIPSYSE 281

  Fly   303 HHMTTVPTPAQSLEG---SCDSSSP-SPSSTSGAA 333
            ...:.|.:|..|.:.   |..|:|| |..||.|||
Frog   282 AKASAVLSPPSSQDSGIISLSSNSPVSNESTKGAA 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsx	NP_001262353.1	DM	41..86	CDD:279137	29/44 (66%)
dsx	NP_001262353.1	DSX_dimer	353..404	CDD:285978
dmrt1	XP_031746577.1	DM	28..74	CDD:395608	30/46 (65%)
dmrt1	XP_031746577.1	Dmrt1	86..158	CDD:403548	16/108 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12322
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4813
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100