Protein Alignment CG10445 and rapA

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_414601.1
• Gene: rapA / 948523
• ECOCYCID: EG11083
• Length: 968
• Species: Escherichia coli
• Alignment Length: 709
• Identity: 137/709 - (19%)
• Similarity: 231/709 - (32%)
• Gaps: 215/709 - (30%)

  Fly   219 WMQFRERQKISGGILADDMGLGKTLSMIALILASEETKNRKRE---EKKKALTLKWTQEFNRVYC 280
            |....|..|...|:          |:.|...|.:||:....||   :.|    |.:::..:|::.
E. coli    67 WQMQVEEVKEENGL----------LTYIGTRLDTEESGVALREVFLDSK----LVFSKPQDRLFA 117

  Fly   281 KEIRKISMFDDEEESGK-EEEQYEPPEKRTCHVKTKKI-NQFRILDDDDNDAGDKAVVEDEQKDL 343
            .:|.::..|.....:.| ..||:..|.......:|..| :|..|..|.......:.::.||..
E. coli   118 GQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVG-- 180

  Fly   344 LAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRH 408
            |.||.|..:..    .:.|.:|  .:...|::.|.::..||..|:..:.   .:|...|......
E. coli   181 LGKTIEAGMIL----HQQLLSG--AAERVLIIVPETLQHQWLVEMLRRF---NLRFALFDDERYA 236

  Fly   409 EIGIEAFRSYD---LVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHII---RNSKTNCCNS 467
            |...:|:..:|   |||.|.:......:|..:   |....|:.:::||||.:   .::.:....:
E. coli   237 EAQHDAYNPFDTEQLVICSLDFARRSKQRLEH---LCEAEWDLLVVDEAHHLVWSEDAPSREYQA 298

  Fly   468 VCQLRAHCHWA--LTGTPVQNRGVDVFALLRFVNVPNFQDLQQW---KKN-----------LNES 516
            :.||..|....  ||.||.|......||.||.::...|.|..|:   :||           |..:
E. coli   299 IEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGN 363

  Fly   517 MLGHRRLNFI--------IKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSA 573
            .|.:..||.:        |:||:       ..|:.|.....|.:.||:               |.
E. coli   364 KLSNDELNMLGEMIGEQDIEPLL-------QAANSDSEDAQSARQELV---------------SM 406

  Fly   574 ISKKIFTQFLLQREKGNS-------DLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGE 631
            :..:..|..:|.|...|.       :|:...|....|              |:..:|
E. coli   407 LMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQ--------------YQTAIK-------- 449

  Fly   632 KILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDET 696
                                   :.|::....:|||
E. coli   450 -----------------------VSGIMGARKSAED----------------------------- 462

  Fly   697 DSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNP 761
                        ..||..:. |.|..|.:.:|..|.:.|  |........|.|.|:.|:|    .
E. coli   463 ------------RARDMLYP-ERIYQEFEGDNATWWNFD--PRVEWLMGYLTSHRSQKVL----V 508

  Fly   762 IFQFIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKER 826
            |......:.:|:.|:.:.|.:....                              |:..::..||
E. coli   509 ICAKAATALQLEQVLREREGIRAAV------------------------------FHEGMSIIER 543

  Fly   827 EIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQ 885
            :.....|...:....:||....|..|.|...|:||::.||.:||.|..|...|:.|.||
E. coli   544 DRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQ 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	137/709 (19%)
		DEAD-like_helicase_N	209..534	CDD:475120	78/349 (22%)
rapA	NP_414601.1	PRK04914	2..966	CDD:235319	137/709 (19%)