Protein Alignment CG10445 and RAD5

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_197667.1
• Gene: RAD5 / 832338
• AraportID: AT5G22750
• Length: 1029
• Species: Arabidopsis thaliana
• Alignment Length: 899
• Identity: 247/899 - (27%)
• Similarity: 380/899 - (42%)
• Gaps: 227/899 - (25%)

  Fly   105 LHLEKL-NARLEALGEFLDTLRLREDQQEIK---------IEDNSELVDHTEQPKWSNLYSGLNR 159
            |.|.|: |...:|.|:        |::|.|.         :.|:|.|.: .|.|  ..|...|..
plant   297 LQLNKVKNMNQDANGD--------ENEQCISDGDLDNIVGVGDSSGLKE-METP--HTLLCELRP 350

  Fly   160 YRQKANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLK-------HQQSCL 217
            |:::|.|...|.  .|.|..|...|:..|......:.|..:    |:|.|..       |..|.|
plant   351 YQKQALHWMTQL--EKGNCTDEAATMLHPCWEAYCLADKRE----LVVYLNSFTGDATIHFPSTL 409

  Fly   218 KWMQFRERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKE 282
                    |...||||||.||||||:..|:|:||.                 .|........|..
plant   410 --------QMARGGILADAMGLGKTVMTISLLLAH-----------------SWKAASTGFLCPN 449

  Fly   283 IRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKT 347
            ..     .|:..|...::...||      ||..|...|           ||.::  |||.:
plant   450 YE-----GDKVISSSVDDLTSPP------VKATKFLGF-----------DKRLL--EQKSV---- 486

  Fly   348 PEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGI 412
                          |.||     ..|:||||:::.||..|:.......::.|...:|.:|.: ..
plant   487 --------------LQNG-----GNLIVCPMTLLGQWKTEIEMHAKPGSLSVYVHYGQSRPK-DA 531

  Fly   413 EAFRSYDLVITSYNLVVNELKRYGNT--SPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHC 475
            :.....|:|||:|.::.:|..:..:.  ..::||.|.|::|||||.|:|||:....:...|.|..
plant   532 KLLSQSDVVITTYGVLTSEFSQENSADHEGIYAVRWFRIVLDEAHTIKNSKSQISLAAAALVADR 596

  Fly   476 HWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESM-----LGHRRLNFIIKPLMLRRT 535
            .|.|||||:||...|:::||||:.:..:.....|.|.:.:..     .|.:.:..|:||:|||||
plant   597 RWCLTGTPIQNNLEDLYSLLRFLRIEPWGTWAWWNKLVQKPFEEGDERGLKLVQSILKPIMLRRT 661

  Fly   536 KQKLQASG-DMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLE 599
            |......| .:..||.....:|..:||::|...|..|...||..|.||:   |:|....||.|
plant   662 KSSTDREGRPILVLPPADARVIYCELSESERDFYDALFKRSKVKFDQFV---EQGKVLHNYAS-- 721

  Fly   600 RTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALT 664
                                                  ||.|||||||.|.||.|:  |.||. |
plant   722 --------------------------------------ILELLLRLRQCCDHPFLV--MSRGD-T 745

  Fly   665 AE--DVQNV-------KVDASDVEGQ------LKMDVLAELDKFDETDSEDDCCDE--ED----- 707
            ||  |:..:       |....:.||:      ...:|:.||.|.::  .|...|.|  ||
plant   746 AEYSDLNKLSKRFLSGKSSGLEREGKDVPSEAFVQEVVEELRKGEQ--GECPICLEALEDAVLTP 808

  Fly   708 ------------STRRDGNFKLEVIKDEI-KEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQ 759
                        |.|...:....|.::.: |:|.:      ..||.|.|:..::          :
plant   809 CAHRLCRECLLASWRNSTSGLCPVCRNTVSKQELI------TAPTESRFQVDVE----------K 857

  Fly   760 NPIFQFIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAK 824
            |.:     .|:|:..::::||. |..:..|.|:.|||.::|.:::..|...::..:..:|.|:.:
plant   858 NWV-----ESSKITALLEELEG-LRSSGSKSILFSQWTAFLDLLQIPLSRNNFSFVRLDGTLSQQ 916

  Fly   825 EREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPT 889
            :||.||::|:.:....|||:||.|||||:||..|::..::|..|||.:|.||..||:|.||||..
plant   917 QREKVLKEFSEDGSILVLLMSLKAGGVGINLTAASNAFVMDPWWNPAVEEQAVMRIHRIGQTKEV 981

  Fly   890 FIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGLNLAELKKLF 943
            .|.|::.:.|||:|::::|..|..:....|.::  ||...     .:.|||.||
plant   982 KIRRFIVKGTVEERMEAVQARKQRMISGALTDQ--EVRSA-----RIEELKMLF 1028

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	235/864 (27%)
		DEAD-like_helicase_N	209..534	CDD:475120	92/338 (27%)
RAD5	NP_197667.1	UBA_like_SF	9..48	CDD:473871
		HIRAN	116..224	CDD:400928
		HepA	<339..1011	CDD:440319	227/822 (28%)
		RING_Ubox	789..842	CDD:473075	9/54 (17%)