Protein Alignment CG10445 and chd9

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_031756017.1
• Gene: chd9 / 733830
• XenbaseID: XB-GENE-1217623
• Length: 2891
• Species: Xenopus tropicalis
• Alignment Length: 996
• Identity: 213/996 - (21%)
• Similarity: 369/996 - (37%)
• Gaps: 332/996 - (33%)

  Fly    63 ASEYNEKKAQIDQLVQKILTMEQQQRQLEENASETKELCDL--KLHLEKLNARLEALGEFL-DTL 124
            :||..||| :|.:|   |:|:.::|::..|::.:..: .|.  ::|.:      |.|.||. .|.
 Frog   572 SSELKEKK-KIGKL---IITLGRKQKRKMESSDDVSD-SDRAPRVHND------EDLQEFAWRTD 625

  Fly   125 RLREDQ---------QEIK----IED----NSELVDHTEQPKWSNLYSGLNRYRQKANHTAAQFY 172
            .|.:||         :::|    :||    .||     ::|| :|:       :.|.|.|:....
 Frog   626 HLHQDQTGSMKRRSNRQVKRKKYVEDVEGKQSE-----DEPK-ANV-------KPKKNSTSLPVE 677

  Fly   173 QHKSNIIDSLKTLYEPIQ---PRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRERQ-KISGGIL 233
            |              |:|   ..|:.:|......:|..|:.|.:.|...:::..|.. |.
 Frog   678 Q--------------PLQLFVENPSEEDAAIVDKILASRIAKKETSSGTFVEVEEYYVKY----- 723

  Fly   234 ADDMGLGKTLSMIALILASEE--TKNRKREEKKKALTLKWTQE-----------FNRVYCK--EI 283
                   |..|.:....|:|:  .|:::..:|.|...::..|.           ||..|.:  .:
 Frog   724 -------KNYSYLHCEWATEQQLLKDKRIHQKIKRFKIRQAQRAHFFADMEEELFNSDYIEVDRV 781

  Fly   284 RKISMFDDEEESGKEEEQY------EPPEKRTCHVKT---------------------------- 314
            .::|:..| :::|:....|      .|.|..|..:|.
 Frog   782 LEVSLCQD-KDTGEPVIYYLVKWCSLPYEDSTWELKEDVDQAKIDEFEQLQALKPDARRVERPPP 845

  Fly   315 ---KKINQFRILDDDDNDAGDK---------------------AVVEDEQKDLLAKTPEPEVFSS 355
               |||||.|     :...|::                     .::.||..  |.||.:...|.
 Frog   846 NSWKKINQSR-----EYKIGNQLREYQLEGLNWLLFNWYNRRNCILADEMG--LGKTIQSITFL- 902

  Fly   356 DEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGIEAFRSY-- 418
              :|.:|:  |.|.. .|::.|:|.:..|..|..:....|   |:.:||.......|:.:..|
 Frog   903 --QEIYLN--RIPGP-FLIIAPLSTIANWEREFRTWTDLN---VVVYHGSMISRQMIQQYEMYFR 959

  Fly   419 -------------DLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQ 470
                         ..:||::.:::      |....|.|:.|..||.||||.::|........:..
 Frog   960 DSQGRIIWGSYKFHAIITTFEMIL------GGCPELNAIEWRCVIFDEAHRLKNKNCKLLEGLKL 1018

  Fly   471 LRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQD----LQQWKKNLNESMLGHRRLNFIIKPLM 531
            :.......|||||:||...::|:||.|:....|..    :|::.....|..:  ::|..|:||:|
 Frog  1019 MNLEHKVLLTGTPLQNTVEELFSLLHFLEPQRFPSESTFMQEFGDLKTEEQV--QKLQAILKPMM 1081

  Fly   532 LRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYY 596
            |||.|:.::..     |...:..:|.|:|:..:...|:   ||.:|.|. ||   .||....|..
 Frog  1082 LRRLKEDVEKK-----LAPKEETIIEVELTNIQKKYYR---AILEKNFA-FL---SKGAGQANVP 1134

  Fly   597 SLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRG 661
            :|..|                                        ::.||:.|.||.|:.|
 Frog  1135 NLVNT----------------------------------------MMELRKCCNHPYLIKG---- 1155

  Fly   662 ALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKE 726
               ||:    |:                |.:|.||.::           ...:|.|:.:
 Frog  1156 ---AEE----KI----------------LGEFRETYNQ-----------MAADFYLQAM------ 1180

  Fly   727 ENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKII 791
                                                   |:.:.|| ::||||...:.....|::
 Frog  1181 ---------------------------------------IQSAGKL-VLIDKLLPKMKAGGHKVL 1205

  Fly   792 VTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVGLNL 855
            :.||.|..|.|:...|....:.....:|::....|:..:..|: .::::.|.||...|||:|:||
 Frog  1206 IFSQMVRCLDILEDYLMHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINL 1270

  Fly   856 NVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLP 920
            ..|:..:|.|..||||.:.|||.|.:|.||.|...:||.:.:::.|:.:......||.:.|.||.
 Frog  1271 TAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLITRNSYEREMFDRASLKLGLDKAVLQ 1335

  Fly   921 EEGGEVTKCVGGGLNLAELKK 941
            ...|. ...|||   :.:|.|
 Frog  1336 SMSGR-ENSVGG---IQQLSK 1352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	192/920 (21%)
		DEAD-like_helicase_N	209..534	CDD:475120	84/417 (20%)
chd9	XP_031756017.1	CDC27	<469..675	CDD:462819	32/126 (25%)
		CD1_tandem_CHD5-9_like	689..753	CDD:349315	14/75 (19%)
		CD2_tandem_CHD5-9_like	774..831	CDD:349310	9/57 (16%)
		PLN03142	859..>1488	CDD:215601	145/653 (22%)
		BRK	2477..2518	CDD:462196
		BRK	2552..2596	CDD:197800