Protein Alignment CG10445 and rad54l2

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_001076824.1
• Gene: rad54l2 / 733747
• XenbaseID: XB-GENE-5829376
• Length: 1396
• Species: Xenopus tropicalis
• Alignment Length: 1061
• Identity: 229/1061 - (21%)
• Similarity: 377/1061 - (35%)
• Gaps: 360/1061 - (33%)

  Fly    11 EIHKQSCSIQDQSSVPVPDS--SGEINNWMEPEPVDSLELSGEYADNESAIFVSASEYNEKKAQI 73
            |..||..:.:.|::....||  .|| ..|........   ||:.:|.      :..:..:|.|.:
 Frog    46 EDDKQDINEKSQNAALGEDSPEQGE-EGWKRSTTSGQ---SGQESDE------AKKKRLQKPANL 100

  Fly    74 DQLVQKILTMEQ--------QQRQLEENASETKELCDLKLHLEKLNARLEALGEFLDTLRLREDQ 130
            .:.::|:|..:|        ||.:||......::..|..|.|......|:.|.|.:: ||..:..
 Frog   101 RRNIRKLLREDQLESVTKTAQQEELERRKRLEQQRKDYPLPLTLPPVSLDFLQEEIE-LRAADVS 164

  Fly   131 QEIK-------------IEDNSELVDHTEQPKWSNLYSG------LNRYRQKANHTAAQFYQHKS 176
            |.:|             .:|..::..|:.:.:...|.||      ::......|..........|
 Frog   165 QLVKSQEIICLDSSSGESDDEGKVKSHSIKDEIIELSSGEEDNLQISDNADSTNEVDGDITTENS 229

  Fly   177 --------NIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLK-HQQSCLKWM-----QFRERQK 227
                    |..|.|..:...|...|...|:...|.  |.|.:| ||...::::     :..||..
 Frog   230 GSHVNDALNQADHLGRVLVNINHPPNEKDIFLAPQ--LARAVKSHQIGGIRFLYDNLVESLERFS 292

  Fly   228 ISGG---ILADDMGLGKTLSMIALI-LASEETKNRKREEKKKALTL-------KWTQEFNRVYCK 281
            .|.|   |||..|||||||.:|:.: :..:.|      ..|..|.:       .|..|||
 Frog   293 GSSGFGCILAHSMGLGKTLQVISFLDVLFQHT------SAKTVLAIVPVNTLQNWLAEFN----- 346

  Fly   282 EIRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVED-------- 338
                  |:....||..::...|..:.|...|.|..       |:....|....||.|
 Frog   347 ------MWLPPPESLPKDHNQELVQPRAFKVHTMN-------DEHKTTAARAKVVNDWATDGGVL 398

  Fly   339 ----EQKDLLA--------------KTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWA 385
                |...||:              |...|.:...|||:..
 Frog   399 LMGYEMYRLLSLKKSFTAGRKKKSKKAAGPVIIDLDEEDRQ------------------------ 439

  Fly   386 HEVASKVAQNAIRVLTFHGPNRHEIGIEAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVI 450
                    |..::            |||                   |......|      :.||
 Frog   440 --------QEMLK------------GIE-------------------KALSRPGP------DVVI 459

  Fly   451 LDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNL-- 513
            .||.|.|:|...:...::..:|:.....|||.|:||..::.:.::.||. |:|...:|...|:
 Frog   460 CDEGHRIKNCHASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVR-PDFLGTRQEFSNMFE 523

  Fly   514 --------------NESMLGHRR--LNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSK 562
                          ::.::.:|.  |:.:::..:.||....|:|.     ||..:..:|.|:|||
 Frog   524 RPILNGQCVDSTPQDKRLMRYRSHVLHSLLEGFVQRRGHTVLKAQ-----LPFKEEHVILVRLSK 583

  Fly   563 TEMAVYQILSAISKKIFTQFLLQ-REKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLG 626
                       |.:.::|:|:.: |:.|||..                               ||
 Frog   584 -----------IQRDLYTEFMNRFRDAGNSGW-------------------------------LG 606

  Fly   627 YNPGEKILGIYILVLLLRLRQF--CC----HPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMD 685
            .||               |:.|  ||    ||    .:|..||..|::.|          :..:|
 Frog   607 LNP---------------LKAFCVCCKIWNHP----DVLYEALQKENLAN----------EQDLD 642

  Fly   686 VLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSA 750
            |       ::..:.:.|      ..:.|..|:|.            :|...|...::...||...
 Frog   643 V-------EDLGTNNRC------NAQSGKIKVEP------------NSLGALMGETAHTKQLQGI 682

  Fly   751 RALKLLNPQ----NPIFQF--------------IRPSAKLKMVIDKLEELLTGTNDKIIVTSQWV 797
                :|||.    |.:..:              ::.|.|:.::...:||.:. ..|||:|.||.:
 Frog   683 ----VLNPSHEKANQVVTYEWAKEILSDYIPGQLQNSPKMVLLFHLIEESMR-MGDKILVFSQSL 742

  Fly   798 SYLAIVR----KR----------------LQDLSWETLDFNGQLTAKEREIVLRDFN-ANNEK-R 840
            |.|:|:.    ||                ::::::..||  |..:|.|||.::..|| .:||| .
 Frog   743 STLSIMEEFLAKRKMPIPAGSDGQEGHTWIRNVNYYRLD--GSTSASERERLINQFNDPSNEKVW 805

  Fly   841 VLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIK 905
            :.|||..||.:|:||..||.:::.|..|||..:.||..|:|||||.||.:|||.:...|:|::|.
 Frog   806 LFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQRKPCYIYRLVSDFTLEKKIY 870

  Fly   906 SLQDCKLEIAKVVLPEEGGEV 926
            ..|..|..::..|:.:...||
 Frog   871 DRQITKQGMSDRVVDDLNPEV 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	202/940 (21%)
		DEAD-like_helicase_N	209..534	CDD:475120	73/385 (19%)
rad54l2	NP_001076824.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..103		14/66 (21%)
		DEXHc_ARIP4	269..545	CDD:350827	71/369 (19%)
		HepA	<272..885	CDD:440319	179/814 (22%)
		DEAH box	461..464		2/2 (100%)
		LXXLL motif 1	549..553		1/3 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1117..1168
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1194..1250
		LXXLL motif 2	1273..1277
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1340..1396