Protein Alignment CG10445 and chd9

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_005169069.3
• Gene: chd9 / 572355
• ZFINID: ZDB-GENE-030131-497
• Length: 2952
• Species: Danio rerio
• Alignment Length: 1103
• Identity: 230/1103 - (20%)
• Similarity: 405/1103 - (36%)
• Gaps: 339/1103 - (30%)

  Fly     2 ESSSPSDTTEIHKQSCSIQDQ-SSVPVPDSSGEINNWMEP--EP-VDSLELSGEYADNESAIFVS 62
            ||||.|......:.|..:::: ..||:..::....|...|  :| |.|..|....:.:.|:   |
Zfish   484 ESSSHSWVNAGVRNSREVKEEVEDVPLVYNAQPPKNTNGPSSQPRVHSPTLKSSSSSSSSS---S 545

  Fly    63 ASEYNEKKAQIDQLVQKILTMEQQQRQLEENASETKELCDLKLHLEKLNARLEALGEFLDTLRLR 127
            :|..:||:.|..:..|:....:|||:|:|...|:.|:        :|.|   ..:.|.:...|.|
Zfish   546 SSYMSEKRLQKQKQQQQQQQQQQQQQQMESPLSDDKQ--------QKAN---RIISEAIAKARER 599

  Fly   128 EDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHTA------------------AQFYQH 174
            .::...::.........:.|.:.....|..::.:.|::..|                  .:|.:.
Zfish   600 GEKNIPRVMSPDSFPSSSSQHRSHKAGSSKSKSKDKSSKKARIVKSSKPKQKAQIGKIVIKFGKK 664

  Fly   175 KSNIIDSLKTLYEPIQP--RPAIDD--------------------------------------LE 199
            |....||.:.|.:..:|  |.:.||                                      ..
Zfish   665 KRKKTDSSEELSDDDRPTRRSSKDDDSKRRSNRKVKRKKYEDDGEARISDEEMKVIVKAKKSSSN 729

  Fly   200 KQPAL-LLVRLLKHQQSCL--KWMQFR-ERQKISGGILA---DDMGLGKTLSMIALILASEE--T 255
            |:||: |.|.....:.:.:  |.|..| .::::|.|:|.   :.....|..|.:....|:|:  .
Zfish   730 KKPAVQLFVENPTEEDAAVVDKIMASRVVKKEVSPGVLVEIEEYFVKYKNYSYLHCEWATEQQLE 794

  Fly   256 KNRKREEKKKALTLKWTQE-----------FNRVYCKEIRKISM-FDDEEESGK----------- 297
            |:::.::|.|...:|..|:           ||..|.:..|.:.: :.::::||:
Zfish   795 KDKRIQQKIKRFKIKQAQKAHFFADIEEDPFNPDYVEVDRVLEVSYCEDKDSGEPVVYYLVKWCS 859

  Fly   298 ---EEEQYEPPEKRTCHVKTKKINQFRILDD--------------------------DDNDAGD- 332
               |:..:|..|    .|...||.:|:.|..                          ::|...|
Zfish   860 LPYEDSTWELME----DVDQTKIEEFKKLQAAKPHTNRMERPPASHWKKLEKSRKYCNENSLRDY 920

  Fly   333 ----------------KAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVM 381
                            ..::.||..  |.||.:...|.   ||.:.:..:.|   .|::.|:|.:
Zfish   921 QLEGVNWLLFNWYNRRNCILADEMG--LGKTIQSITFL---EEIYRTGIKGP---FLIIAPLSTI 977

  Fly   382 CQWAHEVASKVAQNAIRVLTFHGP-------NRHEIGIE---------AFRSYDLVITSYNLVVN 430
            ..|..|..:....|   |:.:||.       .::|:...         |:| :..|||::.:::
Zfish   978 ANWEREFRTWTHLN---VIVYHGSVVSRQMLQQYEMYCRDSQGRVIRGAYR-FQAVITTFEMIL- 1037

  Fly   431 ELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALL 495
                 |....|.|:.|..||:||||.::|...........:.......|||||:||...::|:||
Zfish  1038 -----GGCPELNAIDWRCVIIDEAHRLKNKNCKLLEGFKLMSLEHKVLLTGTPLQNTVEELFSLL 1097

  Fly   496 RFVNVPNFQD----LQQWKKNLNESMLGHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELI 556
            .|:....|..    :|::.....|..:  ::|..|:||:||||.|:.::..     |...:..:|
Zfish  1098 HFLEPTRFPSENTFMQEFGDLKTEEQV--QKLQAILKPMMLRRLKEDVEKK-----LAPKEETII 1155

  Fly   557 CVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERF 621
            .|:|:..:...|:   ||.:|.|: ||   .||....|..:|..|
Zfish  1156 EVELTNIQKKYYR---AILEKNFS-FL---AKGAGQANVPNLLNT-------------------- 1193

  Fly   622 LKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDV 686
                                ::.||:.|.||.|:.|       ||:    |:
Zfish  1194 --------------------MMELRKCCNHPYLIKG-------AEE----KI------------- 1214

  Fly   687 LAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSAR 751
               ::.|.|..|                                       |.|..|..|
Zfish  1215 ---MEDFKEVYS---------------------------------------PAAVDFHLQ----- 1232

  Fly   752 ALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRL--QDLSWET 814
                        ..|:.:.|| ::||||...:.....|:::.||.|..|.|:...|  :...:|.
Zfish  1233 ------------AMIQSAGKL-VLIDKLLPKMKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYER 1284

  Fly   815 LDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQD 878
            :|  |::....|:..:..|: .::::.|.||...|||:|:||..|:..:|.|..||||.:.|||.
Zfish  1285 ID--GRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQA 1347

  Fly   879 RIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGLNLAELKK 941
            |.:|.||.|...:||.:.:::.|:.:......||.:.|.||....|......|||....:|.|
Zfish  1348 RCHRIGQNKAVKVYRLITRNSYEREMFDRASLKLGLDKAVLQSMSGRDNSLAGGGQMQQQLSK 1410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	192/964 (20%)
		DEAD-like_helicase_N	209..534	CDD:475120	86/421 (20%)
chd9	XP_005169069.3	None