Protein Alignment CG10445 and btaf1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_005169589.1
• Gene: btaf1 / 565357
• ZFINID: ZDB-GENE-021025-1
• Length: 1861
• Species: Danio rerio
• Alignment Length: 1062
• Identity: 212/1062 - (19%)
• Similarity: 372/1062 - (35%)
• Gaps: 390/1062 - (36%)

  Fly     5 SPSDTTEIHKQSCSIQDQ------------------SSVPV--PDSSGEINNWMEPEPVDSLEL- 48
            |.|..|:..|:.|.||.:                  .::|.  ...:|.:.|.::.:..||.:|
Zfish  1018 SISTETDESKKPCLIQRRGAEFCLMTVARHFSKELTKTLPYLWESMTGPLRNALDAQEFDSSQLL 1082

  Fly    49 ------SGEYADNESAIFVSASEYNEKKAQI--DQL------------------------VQKIL 81
                  :.:..::...:.|:|...:::...:  :||                        :.||.
Zfish  1083 KQGDSVAQDLVNSLQVLEVTAGAMSQELIPLLMEQLPLLCTCLQHPYTAVRHMAARCVGVLSKIA 1147

  Fly    82 TMEQQQRQLE----------ENASETKELCDLKLHLEKLNARL---------EALGEF---LDTL 124
            |||.....||          :|..:...:..|...:|:|:..:         ..||..   .|::
Zfish  1148 TMETMNVFLEQVLPWLGAIDDNTKQEGAIEALACVMEQLDVDIVPYIVLLVVPVLGRMSDPCDSV 1212

  Fly   125 RLREDQ----------QEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHTAAQFYQHKSNII 179
            |....|          .|..|.|         .|..|   ..|.|.:.:..|...|       ::
Zfish  1213 RFMATQCFATLIRLLPLEAGIPD---------PPSMS---EDLIRQKARERHFLEQ-------LL 1258

  Fly   180 DSLKTLYEPIQPRPAIDDLE--KQPALLLVRLLKHQQSCLKWMQFRERQKISGGILADDMGLGKT 242
            |..|              ||  |.|..:...|.|:||..:.|:.|..:.|:. |||.||||||||
Zfish  1259 DGRK--------------LENYKIPVPIKAELRKYQQDGVNWLAFLNKYKLH-GILCDDMGLGKT 1308

  Fly   243 LSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESGKEEEQYEPPEK 307
            |..|.::......:               .||:.|.                        :.|:
Zfish  1309 LQSICILAGDHFLR---------------AQEYTRT------------------------KAPD- 1333

  Fly   308 RTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANT 372
             :|                                     |.|                     :
Zfish  1334 -SC-------------------------------------PLP---------------------S 1339

  Fly   373 LVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPN------RHEIGIEAFRSYDLVITSYNLVVNE 431
            :||||.::...|..||....::..:..|.:.||.      :|::     :.::|::.||::|.|:
Zfish  1340 IVVCPPTLTGHWVDEVGKFCSKEFLNPLHYTGPPTERARLQHQV-----KKHNLIVASYDVVRND 1399

  Fly   432 LKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLR 496
            ::.:.:      :.:|..||||.|:|:|.||....::.||.|:....|:|||:||..:::::|..
Zfish  1400 VEFFRD------IKFNYCILDEGHVIKNGKTKLSKAIKQLTANYRLILSGTPIQNNVLELWSLFD 1458

  Fly   497 FVNVPNF------------------QDLQQWKKNLNESMLGHRRLNFIIKPLMLRRTKQK-LQAS 542
            |: :|.|                  :|.:...:.....:|....|:..:.|.:|||.|.. ||
Zfish  1459 FL-MPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKDDVLQ-- 1520

  Fly   543 GDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAG 607
             |:|  |.:..:..|            .||.:..:::..|...|.|.|.| :..|...|.:
Zfish  1521 -DLP--PKIIQDYYC------------NLSPLQVQLYEDFAKSRAKVNVD-DVISTASTQE---- 1565

  Fly   608 HMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALT-------- 664
               ||...:     ||:.|          ::...|..||:.|.||.|:       ||
Zfish  1566 ---DEEKPK-----LKATG----------HVFQALQYLRKLCNHPALV-------LTPQHPEYKH 1605

  Fly   665 -AEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEEN 728
             .|.:........|::...|:..|.:|..        ||
Zfish  1606 ITEQLSTQHSSLRDIQHAPKLSALKQLLL--------DC-------------------------- 1636

  Fly   729 VPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKIIVT 793
                   .|.:|.:.:...::..|      |:.:..|    .:||.::|.:|:
Zfish  1637 -------GLGSAGASDSGTEAVVA------QHRVLIF----CQLKSMLDIVEQ------------ 1672

  Fly   794 SQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVA 858
                   .:::.:|..:::..||  |.:.|..|..::..||.:....||||:...||:||||..|
Zfish  1673 -------DLLKPQLPGVTYLRLD--GSVQAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGA 1728

  Fly   859 NHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEG 923
            :.::.|:..|||..:.||.||.:|.||.:...:||.:.:.|:|::|..||..|:.||..|:.:|.
Zfish  1729 DTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMTIANTVISQEN 1793

  Fly   924 GEVTKCVGGGLNLAELKKLFEM 945
            ..:.     .:...:|..||.:
Zfish  1794 ASLQ-----SMGTEQLLNLFTL 1810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	179/863 (21%)
		DEAD-like_helicase_N	209..534	CDD:475120	71/348 (20%)
btaf1	XP_005169589.1	DUF3535	595..1062	CDD:463447	8/43 (19%)
		HEAT repeat	1063..1100	CDD:293787	5/36 (14%)
		HEAT repeat	1110..1146	CDD:293787	2/35 (6%)
		HEAT repeat	1158..1181	CDD:293787	2/22 (9%)
		HEAT repeat	1194..1223	CDD:293787	5/28 (18%)
		HepA	<1241..1790	CDD:440319	170/800 (21%)
		DEXHc_Mot1	1276..1513	CDD:350757	71/348 (20%)