Protein Alignment CG10445 and smarcad1b

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_005155692.3
• Gene: smarcad1b / 563175
• ZFINID: ZDB-GENE-091113-61
• Length: 955
• Species: Danio rerio
• Alignment Length: 1024
• Identity: 200/1024 - (19%)
• Similarity: 380/1024 - (37%)
• Gaps: 294/1024 - (28%)

  Fly    13 HKQSCSIQDQSSVPVPDSSGE-INNWMEPEPV--------DSLEL--------SGEYADNESAIF 60
            |.::.....|.:.|....:.| :.:...|.|:        ||::.        |.:.:|:.....
Zfish    97 HSRTTRSTSQQAQPAHQKASETVTDIAHPSPLKTSGMAAADSVQQRRRQQMCGSSQESDSRKGGR 161

  Fly    61 VSASEYNEKKAQIDQLVQKILTMEQQQRQLEE-NASETKELCDLKLHLEKLNARLEALGEFLDTL 124
            |||::.:|::.|..:..:::|  .:.||:... |.:|.:::  |:.|...::..||.|..|.|.:
Zfish   162 VSAADDSEEEGQRSKDQERML--RKLQRKFPHLNKNELRDV--LQEHDWLIDDALETLRMFSDLV 222

  Fly   125 RLREDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHTAAQFYQHKSNIIDSLKTLYEPI 189
                    ::.||:|   ..|..|.         ::.::...|..|....|         |..|.
Zfish   223 --------VESEDDS---SQTSTPA---------KHTRRVAETRPQAQVTK---------LSSPP 258

  Fly   190 QPRPA--IDD------LEKQPALLLVRLLKHQQSCLKWMQFRERQKISGGILADDMGLGKTLSMI 246
            :|:|:  :|.      :.|||.|.....:..::.|..     ....:..|:|..|..
Zfish   259 KPKPSRPLDGTRTSQRIAKQPILAKYTYVSSEEECSD-----SEASVVNGLLDSDSD-------- 310

  Fly   247 ALILASEETKNRKREE--------KKKALT------LKWTQEFNRVYCKEIRKISMFDDEEESGK 297
                .||||.::.:.|        ....||      ||..|:..     |:|....:.|.:::.:
Zfish   311 ----QSEETLSKLKTEILCFFQSASVDELTLIAGCSLKKAQKIT-----ELRPFKTWKDLDDAMR 366

  Fly   298 EEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTP----EPEVFSSDEE 358
            ............|....|:....:.|.....:...|.:.:..|  ::.|.|    :||:.||..:
Zfish   367 RRNGLSAELLAGCREVLKEREVVKGLMSKCEEISVKLIQDVTQ--VMDKGPGSMTQPEILSSTFQ 429

  Fly   359 ------------------------EEHLSNGR-----------YPSAN---TLVVCPMSVMCQWA 385
                                    .:.:..|:           |...|   .|:..|.|.:..|.
Zfish   430 LKPYQLIGLNWLVLLHQNKLSGILADEMGLGKTIQAISFLAHLYQEGNHGPHLITVPASTLDNWV 494

  Fly   386 HEVASKVAQNAIRVLTFHGP------NRHEIGIEAFRSYDLVITSYNLVVNELKRYGNTS--PLF 442
            .|:  .:...:.:||.::|.      .|:|| :.....|::::::|||.:      ||:|  .||
Zfish   495 REL--NLWCPSFKVLVYYGSADDRKYMRYEI-LNQIVEYNIIVSTYNLAI------GNSSDRSLF 550

  Fly   443 A-VYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNF--- 503
            . :.....:.||.|:::|..:.....:..:.|.....|||||:||..:::.:||.|: :||.
Zfish   551 CKLKLEYAVFDEGHLLKNMNSLRYRHLMAINAKYRLLLTGTPLQNNLLELMSLLNFI-MPNMFSS 614

  Fly   504 ----------QDLQQWKKNLNESMLGHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICV 558
                      ....:.:.:.....:.|.:|  |:||.:|||.|.::     :..||
Zfish   615 STSQIAKMFSMKSSEEQSSFERDRITHAKL--IMKPFILRRVKSEV-----LKQLP--------- 663

  Fly   559 QLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLK 623
              :|.|...:..:|                                       ||..|:|...|.
Zfish   664 --AKEEQVEFCAMS---------------------------------------ERQQELYSALLH 687

  Fly   624 SLGYNP-GEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVL 687
            .|.::. |||   ..:..::::||:...||.|.    |...|.|                |:..:
Zfish   688 KLKHSSNGEK---RELTNVMMQLRKMSNHPLLH----RQFYTTE----------------KLKAM 729

  Fly   688 AELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARA 752
            ::|..             ::.:.||.:..|      |||         |:...|.||       .
Zfish   730 SKLML-------------KEPSHRDADPAL------IKE---------DMEVLSDFE-------L 759

  Fly   753 LKLLNPQNPIFQF------IRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLS 811
            .:|....:.:.::      :..|.||.::...|.. |....|::::.||:...|.|:...|:...
Zfish   760 HRLCQQYSALHEYQLNTDVLLDSGKLSLLTQLLNS-LKEKGDRVVLFSQFTMMLDILEVFLRHHK 823

  Fly   812 WETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQA 876
            ......:|.....:|..::..||.:.:..|.|||..|||:|:||..||.:::.|:..||..::||
Zfish   824 HRYNRLDGSTPMSDRIGLIDQFNTDQDIFVFLLSTRAGGLGINLTSANVVILHDIDCNPYNDKQA 888

  Fly   877 QDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGE 925
            :.|.:|.||||...:.:.:.:|::|..:..:.:.||::.:.:...:.||
Zfish   889 EGRCHRVGQTKTVKVIKLISKDSIEDTMLRIGERKLKLEQEMTATQDGE 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	176/898 (20%)
		DEAD-like_helicase_N	209..534	CDD:475120	74/402 (18%)
smarcad1b	XP_005155692.3	CUE	179..215	CDD:270465	9/39 (23%)
		ComEA	<329..377	CDD:441164	8/52 (15%)
		HepA	<429..926	CDD:440319	126/622 (20%)