Protein Alignment CG10445 and smarcad1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_001015697.1
• Gene: smarcad1 / 548414
• XenbaseID: XB-GENE-492700
• Length: 1003
• Species: Xenopus tropicalis
• Alignment Length: 1043
• Identity: 198/1043 - (18%)
• Similarity: 365/1043 - (34%)
• Gaps: 387/1043 - (37%)

  Fly     2 ESSSPSDTTEIHKQSCSIQD-QSSVPVPDSSG-----EINNWMEPEPVDSLELSGE--------- 51
            :||...|..|  ||..|::. |...|..|...     :.::|...|.:::|:|..|
 Frog   211 DSSLSEDDWE--KQEASVKKLQRHFPDLDKEELREVLQEHDWSFHEALEALKLFAEDETDALQNA 273

  Fly    52 ---------------YADNESAIFVSASEYNEKKAQIDQLVQKILTMEQQQRQLEENAS-ETKEL 100
                           ..||:|:....|:: |..||.....|:|    :.:.::..|||. :|::
 Frog   274 AKKEVSNGKEFSRSNKNDNKSSAKAKANQ-NSNKAMAQNGVKK----KGKGKKYSENAKRDTRD- 332

  Fly   101 CDLKLHLEKLNARLEALGEFLDTLRLRED--------QQEIKIE----------DNSELVDHTEQ 147
                  ||...:..:| |..||     ||        ::|.|.:          |...|:.|...
 Frog   333 ------LESEESASDA-GSCLD-----EDYSSGDEKLEEEYKTKILSFLQDASLDELYLIPHCSH 385

  Fly   148 PK------------WSNLYSGLNRYRQKANHTA------AQFYQHKSNIIDSLKTLYEPI----- 189
            .|            |.:|:..:.    |:|..:      .|....:..::..|....|.|
 Frog   386 KKAQKITELRPFSSWESLFEKMT----KSNGLSEDLIWDCQTLIKEREVVMKLMNKCEEISRTLT 446

  Fly   190 -QPRPAIDDLE-----KQPALLLVRLL--KHQQSCLKWMQFRERQKISGGILADDMGLGKTLSMI 246
             |.....:|.|     :||:::...|:  .:|:..|.|:....:.|:: .||||:||||||:..|
 Frog   447 KQVTQLTEDGECGWNIEQPSIMSENLVLKPYQKIGLNWLALLHKHKVN-MILADEMGLGKTVQAI 510

  Fly   247 A--------------LILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESGK 297
            |              |::....|.:            .|.:|||: :|..: .|.::
 Frog   511 AFLAHLYVTGDSGPHLVVVPASTMD------------NWIREFNQ-WCPSM-NILLY-------- 553

  Fly   298 EEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHL 362
                                                                   :.|.||.:||
 Frog   554 -------------------------------------------------------YGSQEERKHL 563

  Fly   363 SNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGIEAFRSYDLVITSYNL 427
               ||                   ::.:||.:                       :::::|:||.
 Frog   564 ---RY-------------------DILNKVVE-----------------------FNVIVTTYNC 583

  Fly   428 VVNELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVF 492
            .::..:   :.|....:..|..:.||.|:::|........:..|.|.....||||||||..:::.
 Frog   584 AISSAE---DRSLFRRLKLNFAVFDEGHMLKNMSAIRYQHLMTLNARSRLLLTGTPVQNNLLELM 645

  Fly   493 ALLRFVNVPNFQDLQQWKKNL--------------NESMLGHRRLNFIIKPLMLRRTKQKLQASG 543
            :||.||....|.......|.|              .:..:.|.:.  |:||.:|||.|.::
 Frog   646 SLLNFVMPHMFSSSTSEIKRLFSSKAKSTDEQTIFEKERIAHAKQ--IMKPFILRRVKSEV---- 704

  Fly   544 DMPALPSLKIELICVQLSKTEMAVY-QILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAG 607
             :..||..:.::...|:||.:..:| .:|:.:.|                    |::.|
 Frog   705 -LKQLPPKQDKIKFCQMSKKQEQLYSDLLNKLKK--------------------SIDAT------ 742

  Fly   608 HMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVK 672
                |:.:|:..                     :::.||:...||.|.    |...||:
 Frog   743 ----EKNSELCN---------------------VMMHLRKMANHPLLH----RQYYTAD------ 772

  Fly   673 VDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDL 737
                                                       :|..:...:.:|....|:..||
 Frog   773 -------------------------------------------RLRTMSKLMLKEPTHCDANPDL 794

  Fly   738 PTASSFEDQ--LDSARALKLLNPQNPIFQFIRPSAKLKMVIDK-----LEELLTG---TNDKIIV 792
                .|||.  :......:|.|....:.|:   ..:.::::|.     ||:||:.   ..|::::
 Frog   795 ----IFEDMEVMTDFELHRLCNEFTTLSQY---KLEKELILDSGKFNILEKLLSDIKKKGDRVVL 852

  Fly   793 TSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNV 857
            .||:...|.|:...|:......:..:|:....||..::.:||.:.:..:.|||..|||:|:||..
 Frog   853 FSQFTMMLDIIEVFLRHHQHRYVRLDGKTQISERIHLIDEFNTDMDIFIFLLSTKAGGLGINLTS 917

  Fly   858 ANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEE 922
            ||.:::.|:..||..::||:||.:|.||||...:.:.:.:.|:|:.:..:...||.:.:.:...:
 Frog   918 ANIVILHDIDCNPYNDKQAEDRCHRVGQTKEVKVIKLIGKGTIEESMLKISQQKLRLEQDMTTND 982

  Fly   923 GGE 925
            .|:
 Frog   983 TGD 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	167/893 (19%)
		DEAD-like_helicase_N	209..534	CDD:475120	65/354 (18%)
smarcad1	NP_001015697.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..130
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	172..235		8/25 (32%)
		CUE	223..259	CDD:270465	6/35 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	274..351		21/94 (22%)
		HepA	<471..974	CDD:440319	142/746 (19%)
		DEGH box	605..608		2/2 (100%)