Protein Alignment CG10445 and Ino80

DIOPT Version :9

• Sequence 1: NP_001246974.1
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_732413.1
• Gene: Ino80 / 42314
• FlyBaseID: FBgn0086613
• Length: 1638
• Species: Drosophila melanogaster
• Alignment Length: 1082
• Identity: 217/1082 - (20%)
• Similarity: 367/1082 - (33%)
• Gaps: 409/1082 - (37%)

  Fly    85 QQQRQLEENASETKELCDLKLHLEKLN---ARLEALGEFL----------DTLRLRE-------- 128
            :|:|:.||...:..||.::|....|||   .:.|....|:          |.||:..
  Fly   393 KQEREAEEQRKQDVELIEVKRQQRKLNFLITQTELYAHFMSKKLGQGSEEDQLRILSQLDEETNA 457

  Fly   129 --------DQQEIKI--EDNSELVDHTEQPKWSNLYSGLNRYRQKANHTAAQFYQHKSNIIDSLK 183
                    |..|:|:  ::|:|.....:..| :..:....:.::|.....||      ..::.:|
  Fly   458 RLAAQDDYDAGEMKLLAQENAEAAMQRDLDK-TRAFDVFAKKKEKEEEEQAQ------ESVEDIK 515

  Fly   184 TLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRERQKISGGILADDMGLGKTLSMIAL 248
            .     :|||.:.|| .||.:....|..:|...:.|:.....|.|| |||||:||||||:..||.
  Fly   516 P-----EPRPEMKDL-PQPKMFKGTLKGYQIKGMTWLANIYDQGIS-GILADEMGLGKTVQSIAF 573

  Fly   249 ILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESGKEEEQYEPPEKRTCHVK 313
            :                                                            ||:
  Fly   574 L------------------------------------------------------------CHI- 577

  Fly   314 TKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSN-GRYPSANTLVVCP 377
                                                         .||... |.:     ||:.|
  Fly   578 ---------------------------------------------AEHYGVWGPF-----LVISP 592

  Fly   378 MSVMCQWAHEVASKVAQNAIRVLTFHG-PNRHEIGIEAF----------RSYDLVITSYNLVVNE 431
            .|.:..|..|::..|..  .:|:.:.| |...:| :..|          .|:.:|||||.|||::
  Fly   593 ASTLHNWQQEMSRFVPD--FKVVPYWGSPAERKI-LRQFWDQKHLHTRDASFHVVITSYQLVVSD 654

  Fly   432 LKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLR 496
            .|.:..      :.|..::||||..|:::.:.....:..........|:|||:||...:::|||.
  Fly   655 YKYFNR------IKWQYMVLDEAQAIKSAASQRWKLLLGFSCRNRLLLSGTPIQNSMAELWALLH 713

  Fly   497 FVNVPNFQD----LQQW-----------KKNLNESMLGHRRLNFIIKPLMLRRTKQKLQASGDMP 546
            |: :|...|    ..:|           |..::|..:.  ||:.|:||.||||.|:      |:.
  Fly   714 FI-MPTLFDSHDEFNEWFSKDIESHAENKTGIDEKQIS--RLHMILKPFMLRRIKK------DVE 769

  Fly   547 ALPSLKIE-LICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNS------------------- 591
            ...|.||| ::...|:..:..:|:   |:.:||..:.||....|::
  Fly   770 NELSDKIEIMVYCPLTIRQKLLYR---ALKQKIRIEDLLHLTSGSTTTSSSSSASNLMNLVMQFR 831

  Fly   592 ----------------------------------------------------------------- 591
                                                                             
  Fly   832 KVCNHPELFERRDARSPFFMRCAEYTIPRLIHEEGLIHRMLPSRKHLLYNRFNIFKSEYIQRSLF 896

  Fly   592 -DLNYYS---------------------------------LERTP-----QFIAGHMSDERYNEI 617
             |:|..|                                 ||:.|     :|......|.|| ::
  Fly   897 EDVNVNSCFGFTRLCDLSVGDMVEVTLNGLIDFLLHYRRVLEKYPLLAYRRFWWKKQPDSRY-QL 960

  Fly   618 YERFLK---SLGYNPGEKILGIYILVLL---------------LRLRQFCCHPGLMIGMLRGALT 664
            .|..|:   :|.|.|...:|..:|...:               ..:::...|..:...:|:...:
  Fly   961 LEPMLENKLALDYMPPNSVLKNFIFTAMTANESSVYAFGDYFTYNMQETIEHRVIRSKILKKKTS 1025

  Fly   665 ----AEDVQNVKVDASDVEGQ--------LKMDVLAELDKFDETDSEDD--CCDEEDSTR--RDG 713
                .|||...|::...||.|        :|:..|..|.:|.....:..  .|:.....|  .|.
  Fly  1026 LIEEMEDVSKQKLEIESVEVQTKSNAKSDVKVTTLLLLPEFPHRPRKPRKYVCEPLSMPRILYDL 1090

  Fly   714 NFKLEVIK------------DEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFI 766
            ..|::.:.            .:|:........|.:|.::           .|.|..|.......:
  Fly  1091 GQKVQAVHRYLYCDSRSAAWSQIRHNQCENSQGRELVSS-----------GLALCKPHGGWSSIV 1144

  Fly   767 RP--------SAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWE------TLDF 817
            .|        :.|| .|:|.|...|.....::::.||....:.:    |::..|.      .||.
  Fly  1145 VPDKETLITDAGKL-FVLDNLLTRLKANGHRVLIYSQMTKMIDL----LEEYMWHRKHRYMRLDG 1204

  Fly   818 NGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYR 882
            :.:::|: |::| .||....:..|.|||..|||:|:||..|:.::..|..|||.:::||.||.:|
  Fly  1205 SSKISAR-RDMV-ADFQTRADIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHR 1267

  Fly   883 YGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGG 924
            .||||...:||.:|:.|:|:||......|.||.::|:  .||
  Fly  1268 LGQTKQVTVYRLICKGTIEERILQRAREKSEIQRMVI--SGG 1307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_001246974.1	HepA	<90..945	CDD:223627	215/1077 (20%)
		DEAD-like_helicase_N	209..534	CDD:421690	74/351 (21%)
Ino80	NP_732413.1	DBINO	313..438	CDD:290603	12/44 (27%)
		SNF2_N	538..840	CDD:278600	89/434 (21%)
		DEXDc	555..700	CDD:238005	49/265 (18%)
		Helicase_C	1156..1269	CDD:278689	37/119 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467130
Domainoid	1	1.000	47	1.000	Domainoid score	I705
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.930