Protein Alignment CG10445 and Etl1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 918
• Identity: 204/918 - (22%)
• Similarity: 357/918 - (38%)
• Gaps: 287/918 - (31%)

  Fly    50 GEYADNESAIFVSASEYNEKKAQI----DQLVQKILTMEQQQRQLEE--NASETKELCDLKLHLE 108
            |.::||:.:   ...:..:.|.|:    |...:....|..|::::.:  |.:...||..:|...|
  Fly   146 GNFSDNDHS---DDDDVKQSKDQVYDSDDSDSEMSTKMTGQRKKVFQFMNEASLIELQSVKTLSE 207

  Fly   109 KLNARLEALGEFLDTLRLREDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHTAAQFYQ 173
            |....:..:..|.|...||:..:.|::  :.:|:::.::.        :|:     .:|.|....
  Fly   208 KKALAIIDVRPFSDWSDLRQKLESIRM--SGDLLNYAQEL--------INK-----QNTVAAILS 257

  Fly   174 HKSNIIDSLKTLYEPIQPRPAIDD---LEKQPALLL--VRLLKHQQSCLKWMQFRERQKISGGIL 233
            ..:|::..|:         .||.:   :.:||.||.  ::|..:|...|.|:....:|::: |||
  Fly   258 KCNNMVSRLE---------KAISNGAGIVEQPKLLSSGLQLADYQIIGLNWLTVMHKQEMN-GIL 312

  Fly   234 ADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESGKE 298
            ||:||||||:.:||.:                            .|.||
  Fly   313 ADEMGLGKTIQVIAFL----------------------------AYLKE---------------- 333

  Fly   299 EEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLS 363
                                                                             
  Fly   334 ----------------------------------------------------------------- 333

  Fly   364 NGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPN------RHEIGIEAFRSYDLVI 422
            ||...:|: |:|.|.|.:..|..|::....:  :.|..:||..      |.....:.|..:|:::
  Fly   334 NGLSQAAH-LIVVPSSTLDNWEAEISRWCPE--LVVEKYHGSQDERRRMRGRFAKDGFTGFDVLL 395

  Fly   423 TSYNLVVNELKRYGNT---SPLFAV-YWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTP 483
            |:|::|       |:|   ..:|.| ..:.||.||||:::|..|....::..:.|.....|||||
  Fly   396 TTYHIV-------GSTPEERKMFRVCKLDYVIFDEAHMLKNMTTQRYANLITINARMRILLTGTP 453

  Fly   484 VQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESMLGHRRLNFIIKPLMLRRTKQKLQASGDMPAL 548
            :||..:::.:||.|| :|.|     :.|::.:           ||.|..::.|    :.||...:
  Fly   454 LQNNLLELISLLCFV-MPKF-----FAKSIED-----------IKSLFAKKGK----SDGDQDEV 497

  Fly   549 PSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREK----GNSDLNYYSLERTPQFIAGHM 609
            .         |..:|     ||..|  |:|...|:|:|.|    .|.......:|:.|      |
  Fly   498 S---------QFQET-----QIQRA--KRIMKPFVLRRLKKDVLKNLPKKLSLVEKVP------M 540

  Fly   610 SDER---YNEIYERFLKSLGYNPGE-----KILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAE 666
            |.::   |:|:.:.:    ..|.||     :..||   .:::.:|:...||.||
  Fly   541 SSQQKIYYHELVDYY----SNNKGEVCSSSERAGI---AIMMEMRRIANHPLLM----------- 587

  Fly   667 DVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPW 731
              ::...|| ::.|..|.  ||....|.:|:  :....||.:...|......:.|.|..:..:|
  Fly   588 --RHYFTDA-NLRGFSKR--LANASSFKKTN--EQYIFEELAVMSDFQVYQMMNKHEFYDVKIP- 644

  Fly   732 DSGDDLPTASSFEDQL--DSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKIIVTS 794
                         |.|  ||.:.|.|                     |.|...|.....::::.|
  Fly   645 -------------DNLICDSGKFLYL---------------------DTLLPKLKAEGHRVLLFS 675

  Fly   795 QWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVAN 859
            |:...|.||.:.|:...:.....:|......|:.::.|||.::...|.|||..|||||:||..|:
  Fly   676 QFTMMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDFNGDDSIFVFLLSTKAGGVGINLTAAD 740

  Fly   860 HMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGG 924
            ..:|.|:.:||..::||:||.:|.||.:|..|||.:.:.|:|:.|....:.||::.|.:...|.|
  Fly   741 TCVIHDIDFNPYNDKQAEDRCHRMGQQRPVTIYRLISESTIEEGILMAAEEKLKLEKDITSNEKG 805

  Fly   925 EV--TKCV 930
            ||  .:||
  Fly   806 EVHEQRCV 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	184/834 (22%)
		DEAD-like_helicase_N	209..534	CDD:475120	69/334 (21%)
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	10/40 (25%)
		HepA	<276..795	CDD:440319	170/741 (23%)