Protein Alignment CG10445 and Marcal1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 875
• Identity: 175/875 - (20%)
• Similarity: 280/875 - (32%)
• Gaps: 346/875 - (39%)

  Fly   147 QPKWSNLYSGLNRYRQKANHTAAQFYQH----KSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLV 207
            |.|.|.|.:.......|:..:|....||    |||          |.||:      .|.|
  Fly    21 QAKKSQLLASAPATNGKSTTSATGATQHANNGKSN----------PNQPQ------AKSP----- 64

  Fly   208 RLLKHQQSCLKWMQFRERQKI--SGGILADDMGLGKTLSMIALILASEETKNRK----------- 259
              |...:|     ...|::||  ||....|:    |:.|.:..:.|.::|.||:
  Fly    65 --LNFYRS-----PTGEQKKINRSGPTPGDN----KSSSFLNALKAIKQTSNRELSRGAAHPYQR 118

  Fly   260 ----REEKKKALTLKWTQE-------FNRVYCKEIRKISMFDDEEESGKEEEQY-----EPPEKR 308
                .|..|..|:|...:|       .|.:.| .:..||......::....||.     ..|.|
  Fly   119 PNGGNERNKPTLSLSSDKEKPVAVLLGNSITC-NLYLISTHRFAAQTSGYHEQLVTVFKNMPTK- 181

  Fly   309 TCHVKTKKINQFRILDDDD--NDAGD-----------KAVVEDEQKDLLAK---TPEPEVFSSDE 357
             |:....:|..|.:.|...  ..|.|           |.|:     ||..:   .||..|.:|.|
  Fly   182 -CYDGQTRIWSFDLSDYQSLKTHAADLKPYVHMNGIPKKVL-----DLCGQPPVVPERSVLASIE 240

  Fly   358 EE--------------------------EHLSNGRYPSANT----------LVVC-PMSVMCQWA 385
            .:                          :.:..|:...|..          |:|| ..|....||
  Fly   241 PKLADQLMPFQQDGVCFAIAQKGRIMICDEMGLGKTYQALAVADYFKDDWPLLVCTTASTRDSWA 305

  Fly   386 HEVAS---KVAQNAIRVLTFHGPNRHEIGI-EAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYW 446
            ..:..   ||..:.::||     |.:::.: ||    .::|||||:    ::|:  ...|....:
  Fly   306 KHIMDLLPKVPIHYVQVL-----NNNQLYVGEA----KVLITSYNM----MERH--EDKLMQRKF 355

  Fly   447 NRVILDEAHIIRNSKTNCCNSVCQL--RAHCHWALTGTPVQNRGVDVFALL-----RFVNVPNF- 503
            ..:|.||:|.::|||..|..:..:|  :|.....|:|||..:|.:::|..|     :|:|...|
  Fly   356 GFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQMIDGKFMNFMEFT 420

  Fly   504 -------QDLQQWKKNLNESMLGHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQ-- 559
                   |....|..| .:|.|...::...:| .||||||.::     :|.|.....|.:.:.
  Fly   421 TRYCDGKQSTFGWDAN-GQSNLEELKVILHLK-YMLRRTKVEV-----LPQLAEKNRETVVLDPA 478

  Fly   560 LSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKS 624
            |..|.....:.|.|.:|:      |:..||.:.                      .||..||
  Fly   479 LVWTNAETKETLDAFNKE------LKTAKGRAT----------------------EEILLRF--- 512

  Fly   625 LGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAE 689
                        |.....::.|..|.:
  Fly   513 ------------YARTAEVKTRAVCAY-------------------------------------- 527

  Fly   690 LDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALK 754
                                          :|..:||:.                         |
  Fly   528 ------------------------------LKTLVKEQK-------------------------K 537

  Fly   755 LLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNG 819
            .:     ||      |..::::|.:.:.|:|..         |.|:.|               :|
  Fly   538 FI-----IF------AHHRVMMDAISDFLSGLK---------VHYIRI---------------DG 567

  Fly   820 QLTAKEREIVLRDFNANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYG 884
            |..:..|...:..|...:..:|.||||.|...|:.|..|..::..:|.|||....||:.|.:|.|
  Fly   568 QTRSDHRSDSVDTFQKKSSCKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIG 632

  Fly   885 QTKPTFIYRYM-----CQDTVEQRIKSLQD 909
            ||||. |.||:     ..|.:...:|:.|:
  Fly   633 QTKPV-ICRYLIAHNTADDIIWNMLKNKQE 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	175/875 (20%)
		DEAD-like_helicase_N	209..534	CDD:475120	92/425 (22%)
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	10/57 (18%)
		HepA	<233..666	CDD:440319	120/623 (19%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	50/225 (22%)