Protein Alignment CG10445 and Chd2

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_063118674.1
• Gene: Chd2 / 308738
• RGDID: 1310056
• Length: 1840
• Species: Rattus norvegicus
• Alignment Length: 936
• Identity: 180/936 - (19%)
• Similarity: 321/936 - (34%)
• Gaps: 391/936 - (41%)

  Fly    33 EINNWM---EPEPVDSLELSGEYADNESAIFVSASEYNEKKAQIDQLVQKILTMEQQQRQLEENA 94
            ||..|:   .||.|       ||.:.:..:   |||.|::.    |:|::::.::..:
  Rat   360 EIKQWLGKVSPEDV-------EYFNCQQEL---ASELNKQY----QIVERVIAVKTSK------- 403

  Fly    95 SETKELCDLKLHLEKLNARLEALGEFLDTLRLREDQQEIKIEDNSELVDHTEQP----------K 149
                                .|||:                   ::...|:.:|          |
  Rat   404 --------------------SALGQ-------------------TDFPAHSRKPAPSNEPEYLCK 429

  Fly   150 WSNLYSGLNRYRQKANHTAAQFYQHKSNIIDSL------KTL----YEPIQPRPAIDDLEKQPAL 204
            |..|     .|.:.:....|...:...:.|||.      ||:    .:.::.||....|:||||.
  Rat   430 WMGL-----PYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAY 489

  Fly   205 L---LVRLLKHQQSCLKWMQFRERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKA 266
            |   .:.|..:|...|.|:. ....|.:..||||:||||||:..|:
  Rat   490 LGGENLELRDYQLEGLNWLA-HSWCKSNSVILADEMGLGKTIQTIS------------------- 534

  Fly   267 LTLKWTQEFNRVYCKEIRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAG 331
                                                                             
  Rat   535 ----------------------------------------------------------------- 534

  Fly   332 DKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHE--------- 387
                                 |.|....:|...|.:     |:|.|:|.:..|..|
  Rat   535 ---------------------FLSYLFHQHQLYGPF-----LIVVPLSTLTSWQREFEIWAPEVN 573

  Fly   388 ----VASKVAQNAIRVLTF-HGPNRHEIGIEAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWN 447
                :...:::|.||...: |...:.       ..::.:||:|.:::.:      .:.|.::.|.
  Rat   574 VVVYIGDLMSRNTIREYEWIHSQTKR-------LKFNALITTYEILLKD------KTVLGSINWA 625

  Fly   448 RVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKN 512
            .:.:||||.::|..:....::...:::....:||||:||...::::||.|:....|:..:.::::
  Rat   626 FLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEED 690

  Fly   513 LNESM-LGHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISK 576
            ..:.. .|::.|:.:::|.:|||.|:.::.|  :||    |:|    |:.:.||      ||:.|
  Rat   691 HGKGRENGYQSLHKVLEPFLLRRVKKDVEKS--LPA----KVE----QILRVEM------SALQK 739

  Fly   577 KIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVL 641
            :.: :::|.|       ||.:|.:..:
  Rat   740 QYY-KWILTR-------NYKALAKGTR-------------------------------------- 758

  Fly   642 LLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDE- 705
                           |...|.|                     :::.||.|         ||:.
  Rat   759 ---------------GSTSGFL---------------------NIVMELKK---------CCNHC 778

  Fly   706 ------EDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQ 764
                  |||.|..|.   ||::                                          .
  Rat   779 YLIRAPEDSERETGQ---EVLQ------------------------------------------S 798

  Fly   765 FIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIV 829
            .||.|.|| :::|||...|....:::::.||.|..|.|:.:.|....:.....:|.:..:.|:..
  Rat   799 LIRSSGKL-ILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQA 862

  Fly   830 LRDFNAN-NEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYR 893
            |..|||: :|....|||..|||:|:||..|:.::|.|..||||.:.|||.|.:|.||.|...|||
  Rat   863 LDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYR 927

  Fly   894 YMCQDTVEQRIKSLQDCKLEIAKVVL 919
            .:.:.|||:.|......|:.:..:|:
  Rat   928 LVTKGTVEEEIIERAKKKMVLDHLVI 953

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	165/851 (19%)
		DEAD-like_helicase_N	209..534	CDD:475120	54/339 (16%)
Chd2	XP_063118674.1	None