Protein Alignment CG10445 and Smarca5

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_001424549.1
• Gene: Smarca5 / 307766
• RGDID: 1308832
• Length: 1072
• Species: Rattus norvegicus
• Alignment Length: 862
• Identity: 179/862 - (20%)
• Similarity: 294/862 - (34%)
• Gaps: 344/862 - (39%)

  Fly   143 DHTEQPKWSNLYSGLNRYRQKANHTAAQFYQHKSNIIDSLKTLYEPIQ---PRPAIDDLEKQPAL 204
            |.|.:.|.....:....|..|.....|.|.|..:.     ||...|::   .||.:...||| .|
  Rat    76 DPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQ-----KTPTSPLKMKPGRPRVKKDEKQ-NL 134

  Fly   205 LLVRLLKHQQ---------------------------SCLKWMQFRERQKISG------------ 230
            |.|...:|::                           |.:||.:.|:.| :.|
  Rat   135 LSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQ-VRGLNWLISLYENGI 198

  Fly   231 -GILADDMGLGKTLSMIALILASEETKNRKREEK---KKALTLKWTQEFNRVYCKEIRKISMFDD 291
             |||||:|||||||..|:|:...:..:|......   .|:....|..||.| :...:|.:.:..|
  Rat   199 NGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKR-WVPTLRSVCLIGD 262

  Fly   292 EEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSD 356
            :|:..                                     |.|.|
  Rat   263 KEQRA-------------------------------------AFVRD------------------ 272

  Fly   357 EEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGIEAFRSYDLV 421
                             |:.|    .:|                                  |:.
  Rat   273 -----------------VLLP----GEW----------------------------------DVC 282

  Fly   422 ITSYNLVVNE---LKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTP 483
            :|||.:::.|   .|::.         |..:::||||.|:|.|:.....|.:.:......|||||
  Rat   283 VTSYEMLIKEKSVFKKFN---------WRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTP 338

  Fly   484 VQNRGVDVFALLRFVNVPNF----QDLQQWKKNLNESMLGHR----RLNFIIKPLMLRRTKQKLQ 540
            :||...::::||.|: :|:.    .|...|....|  .||.:    ||:.:::|.:|||.|..::
  Rat   339 LQNNLHELWSLLNFL-LPDVFNSADDFDSWFDTNN--CLGDQKLVERLHMVLRPFLLRRIKADVE 400

  Fly   541 ASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFI 605
            .|     ||           .|.|:.:|..||.:.::.:|:.|::      |::..:       .
  Rat   401 KS-----LP-----------PKKEVKIYVGLSKMQREWYTRILMK------DIDILN-------S 436

  Fly   606 AGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQN 670
            ||.|...|                        :|.:|::||:.|.||.|..|
  Rat   437 AGKMDKMR------------------------LLNILMQLRKCCNHPYLFDG------------- 464

  Fly   671 VKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGD 735
                                                                  .|...|:.:..
  Rat   465 ------------------------------------------------------AEPGPPYTTDM 475

  Fly   736 DLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVI-DKLEELLTGTNDKIIVTSQWVSY 799
            .|.|.|.                              |||: |||...|.....::::.||....
  Rat   476 HLVTNSG------------------------------KMVVLDKLLPKLKEQGSRVLIFSQMTRV 510

  Fly   800 LAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVGLNLNVANHMLI 863
            |.|:.......::|....:||....||:..:..:| .|:.|.|.:||..|||:|:||..|:.:::
  Rat   511 LDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVIL 575

  Fly   864 VDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTK 928
            .|..||||::.||.||.:|.||||...::|::..:|||:||....:.||.:..:|: ::|    :
  Rat   576 YDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVI-QQG----R 635

  Fly   929 CVGGGLNLAELKKLFEM 945
            .|...||.....::.:|
  Rat   636 LVDQNLNKIGKDEMLQM 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	173/834 (21%)
		DEAD-like_helicase_N	209..534	CDD:475120	71/378 (19%)
Smarca5	NP_001424549.1	None