Protein Alignment CG10445 and Chd9

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_038953982.1
• Gene: Chd9 / 307726
• RGDID: 1306795
• Length: 2883
• Species: Rattus norvegicus
• Alignment Length: 1064
• Identity: 214/1064 - (20%)
• Similarity: 392/1064 - (36%)
• Gaps: 305/1064 - (28%)

  Fly     5 SPSDTTEIHKQS----CSIQDQSSVPVPDSSG--------EINNWMEPEPVDSLELSGEYADNES 57
            ||...:..|..|    |..:...|....|.||        ::....|.:|....|...:   .|.
  Rat   463 SPLPNSHQHVPSRSHLCLQRQPPSSKKSDGSGTYSRLQNTQVRVMSEKKPRKKAESESK---QEK 524

  Fly    58 AIFVSASEYNEKKAQIDQLVQKILTME---------QQQRQLEENASETKELCDLKLHLEKLNAR 113
            |..:.:......|.:.::.:.::::.|         :::::.:...|:.|:..:.|   .|..::
  Rat   525 ANRIISEAIARAKERGERNIPRVMSPENFPSSSVDGKEEKRAQRVKSKPKDRDNRK---PKACSK 586

  Fly   114 LE---ALGEFLDTL---RLREDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHTAAQFY 172
            |:   .:|:.:.||   ..|..:...::.|..::..||.:.:.|.......:.::|.....|:..
  Rat   587 LKEKTKIGKLIITLGKNHKRRSESSDELSDAEQMPQHTFKEQHSQKRRSNRQVKRKKYAEDAEGR 651

  Fly   173 QHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCL--KWMQFRE-RQKISGGILA 234
            |.:..:..||| :.....|.|.     :||..|.|.....:.:.:  |.:..|. ::::|.|::.
  Rat   652 QCEEEVRGSLK-VKRTSAPPPG-----EQPLQLFVENPSEEDAAIVDKILACRTVKKEVSPGVML 710

  Fly   235 DDMGL---GKTLSMIALILASEE--TKNRKREEKKKALTLKWTQE-----------FNRVYCKEI 283
            |....   .|..|.:....|:|:  .|:::.::|.|...|:..|.           ||..|.:..
  Rat   711 DIEEFFVKYKNYSYLHCEWATEQQLLKDKRIQQKIKRFKLRQAQRAHFLADMEEEPFNPDYVEVD 775

  Fly   284 RKISM-FDDEEESGKEEEQY------EPPEKRTCHVK----TKKINQFRILDDDDNDAGDKAVVE 337
            |.:.: |.:::::|:....|      .|.|..|..:|    ..||.:|..|.....|.
  Rat   776 RILEVSFCEDKDTGESVVYYLVKWCSLPYEDSTWELKEDVDLAKIEEFEQLQASRPDT------- 833

  Fly   338 DEQKDLLAKTPEPEVFSSDEEEEHLSNGR-----------------YPSANT------------- 372
             .|.|    .|...::...::.....||.                 |...|.
  Rat   834 -RQLD----RPPSNIWKKIDQSREYKNGNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQ 893

  Fly   373 -----------------LVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGP-------NRHEIGIE 413
                             |::.|:|.:..|..|..:   ...|.|:.:||.       .::|:...
  Rat   894 SITFLYEVLLTGIRGPFLIIAPLSTIANWEREFRT---WTDINVVVYHGSLISRQMIQQYEMYFR 955

  Fly   414 ---------AFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVC 469
                     |:| :..:||::.:::      |....|.|:.|..||:||||.::|........:.
  Rat   956 DSQGRIIRGAYR-FQAIITTFEMIL------GGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLK 1013

  Fly   470 QLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQD----LQQWKKNLNESMLGHRRLNFIIKPL 530
            .:.......|||||:||...::|:||.|:....|..    :|::.....|..:  ::|..|:||:
  Rat  1014 LMNLEHKVLLTGTPLQNTVEELFSLLHFLEPLRFPSESTFMQEFGDLKTEEQV--QKLQAILKPM 1076

  Fly   531 MLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNY 595
            ||||.|:.::     ..|...:..:|.|:|:..:...|:   ||.:|.|: ||   .||....|.
  Rat  1077 MLRRLKEDVE-----KRLAPKEETIIEVELTNIQKKYYR---AILEKNFS-FL---SKGAGQTNV 1129

  Fly   596 YSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLR 660
            .:|..|                                        ::.||:.|.||.|:.|
  Rat  1130 PNLVNT----------------------------------------MMELRKCCNHPYLIKG--- 1151

  Fly   661 GALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIK 725
                ||:    |:                :.:|.:|.:
  Rat  1152 ----AEE----KI----------------IGEFRDTYN--------------------------- 1165

  Fly   726 EENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKI 790
                        |:||.|..|                 ..|:.:.|| ::||||...:.....|:
  Rat  1166 ------------PSASDFHLQ-----------------AMIQSAGKL-VLIDKLLPKMKAGGHKV 1200

  Fly   791 IVTSQWVSYLAIVRKRL--QDLSWETLDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVG 852
            ::.||.|..|.|:...|  :...:|.:|  |::....|:..:..|: .::::.|.||...|||:|
  Rat  1201 LIFSQMVRCLDILEDYLIHKRYLYERID--GRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLG 1263

  Fly   853 LNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKV 917
            :||..|:..:|.|..||||.:.|||.|.:|.||.|...:||.:.:::.|:.:......||.:.|.
  Rat  1264 INLTAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKA 1328

  Fly   918 VLPEEGGEVTKCVGGGLNLAELKK 941
            ||....|..:...|    :.:|.|
  Rat  1329 VLQSMSGRDSNVSG----IQQLSK 1348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	188/911 (21%)
		DEAD-like_helicase_N	209..534	CDD:475120	82/421 (19%)
Chd9	XP_038953982.1	KLF3_N	217..375	CDD:410554
		PTZ00121	<510..>765	CDD:173412	45/266 (17%)
		CD1_tandem_CHD5-9_like	685..749	CDD:349315	12/63 (19%)
		CD2_tandem_CHD5-9_like	769..827	CDD:349310	12/57 (21%)
		PLN03142	858..>1479	CDD:215601	138/645 (21%)
		BRK	2475..2515	CDD:462196
		BRK	2549..2593	CDD:197800