Protein Alignment CG10445 and btf-1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_496802.2
• Gene: btf-1 / 174965
• WormBaseID: WBGene00000274
• Length: 1649
• Species: Caenorhabditis elegans
• Alignment Length: 954
• Identity: 218/954 - (22%)
• Similarity: 333/954 - (34%)
• Gaps: 359/954 - (37%)

  Fly    74 DQLVQKILTMEQQQ----RQLEENASET--KELCD------------LKLHLEKLNARLEALGEF 120
            ||...||.::...:    |.....|.||  |..|.            |...|:.:|:||.|:..|
 Worm   937 DQSADKIFSLVPSEDPAIRYAFAKAIETFFKSSCGDTLSKCYNRLVVLSKDLDNVNSRLSAVEVF 1001

  Fly   121 L-----DT--------------LRLREDQQEIKIEDNSEL------VDHTEQPKWSNLYSGLNR- 159
            |     ||              ..|..||.|...:...|.      |...|.|.:|  ..|:::
 Worm  1002 LRLCMMDTRYLNGWATLLAPVIFPLLADQCETVRDAAGEAFRRLIPVITLENPDFS--IEGMSQE 1064

  Fly   160 -YRQKANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFR 223
             ..:|:.      |.:..|::.|..:|     ||....|:.......::|  ::|...:.|::|.
 Worm  1065 LLAKKSE------YSNFINVLGSPSSL-----PRVIRADIRGGFDTSMLR--EYQLEGITWIRFL 1116

  Fly   224 ERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISM 288
            ....:. |||||||||||||..:..|..|.:     |:|         ..||:|
 Worm  1117 RTYGLH-GILADDMGLGKTLQTMCSIALSVD-----RDE---------MSEFHR----------- 1155

  Fly   289 FDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVF 353
                                 |
 Worm  1156 ---------------------C------------------------------------------- 1156

  Fly   354 SSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHE---------VASKVAQNAIRVLTFHGPNRHE 409
                              :|:|||.:::..|..|         .|||   |..|.   ||.
 Worm  1157 ------------------SLIVCPRTLVDHWCLEWNRFFPQRVPASK---NLTRC---HGA---- 1193

  Fly   410 IGIEAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAH 474
                     ::.:.:|    :|||    |:.:....||.::|||.|::||||........||...
 Worm  1194 ---------EICVIAY----DELK----TAYMMDRVWNYIVLDEGHVMRNSKLRAWKFASQLVGK 1241

  Fly   475 CHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESMLGHR---RLNFIIKPLMLRRTK 536
            ....|:||||||...|:::|..:: :|.:              ||..   |..|:.|.:..|..|
 Worm  1242 SRLILSGTPVQNSPADLWSLFAWL-MPGY--------------LGSEKQFRSQFLKKIMKCRLPK 1291

  Fly   537 QKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERT 601
            ..   ..|:.| .|..|.    ||.|.      :|..:.:::.|:.|  :|....::..|..|.|
 Worm  1292 AN---EADLKA-GSAAIS----QLHKL------VLPFVMRRLKTEVL--KELPEKNVQDYECELT 1340

  Fly   602 PQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLM------IG--- 657
                      |...||| ||:.....:..|.: |:..||.|:.||:...|..|:      ||
 Worm  1341 ----------EDQKEIY-RFVVDRCTSSQEDV-GLSSLVTLITLRKLTDHTKLVHDTLAKIGAPQ 1393

  Fly   658 -MLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIK 721
             :|..||.|:..              ||:.|.:|                       ..:.|:.|
 Worm  1394 YILSKALAAKSG--------------KMEALKQL-----------------------LIECEICK 1421

  Fly   722 DEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGT 786
            :..:|...|.|.|..:.:..         |||        ||...:.||||  |.|.|:   :|.
 Worm  1422 NPDEEVEQPEDLGGLVASGH---------RAL--------IFCQWKTSAKL--VSDALK---SGE 1464

  Fly   787 NDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKRVLLLSLTAGGV 851
            ...:      ||:|.:               :|.:.|.:|..::..||.:....||:|:...|||
 Worm  1465 FGSV------VSHLVL---------------DGSVPAGDRMKMVNRFNEDKTIDVLILTTHVGGV 1508

  Fly   852 GLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAK 916
            ||||..|:.::.:|..|||..:.||.||.:|.|||:...:||.:.|.|||:::.||...||..|:
 Worm  1509 GLNLTGADTVIFLDHDWNPMKDLQAIDRAHRLGQTRNVNVYRLITQGTVEEKVMSLAKFKLNTAQ 1573

  Fly   917 VVLPE-------------------EGGEVTKCVGGGLNLAELKK 941
            .::..                   :|.|..|..|||...|:..|
 Worm  1574 ALIGADNTSMMTMETGELMNMFTLDGDEAKKKPGGGEPAAKKSK 1617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	197/854 (23%)
		DEAD-like_helicase_N	209..534	CDD:475120	69/336 (21%)
btf-1	NP_496802.2	DUF3535	<572..>792	CDD:463447
		HepA	<1102..1577	CDD:440319	172/734 (23%)