Protein Alignment CG10445 and rad-54.L

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_492438.1
• Gene: rad-54.L / 172728
• WormBaseID: WBGene00004298
• Length: 818
• Species: Caenorhabditis elegans
• Alignment Length: 791
• Identity: 148/791 - (18%)
• Similarity: 261/791 - (32%)
• Gaps: 328/791 - (41%)

  Fly   209 LLKHQQSCLKWM----------QFRERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEK 263
            |..||:..:|:|          :|.      |.|:||:|||||||..|:|:
 Worm   202 LRPHQRDGVKFMWDCVTGINIPEFH------GCIMADEMGLGKTLQCISLL-------------- 246

  Fly   264 KKALTLKWTQEFNRVYCKEIRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDN 328
                   ||
 Worm   247 -------WT-------------------------------------------------------- 248

  Fly   329 DAGDKAVVEDEQKDLLAKTPE--PEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASK 391
                          ||.::|:  |.|                 :.:::|||.|::..|..|: .|
 Worm   249 --------------LLRQSPDACPTV-----------------SKSIIVCPSSLVKNWDKEI-KK 281

  Fly   392 VAQNAIRVLTFHGPNRHEIGIEAFRSY----------DLVITSYNLVVNELKRYGNTSPLFAVYW 446
            .....:..:......|.:| |....|:          .::|.||.              .|.:|.
 Worm   282 WLGTRLNAMPVDSGKREQI-IACLNSFMADSKMRCAIPVLIISYE--------------TFRLYA 331

  Fly   447 N--------RVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNF 503
            |        .||.||.|.::||:.....::..|:......::|||:||..::.|:|:.|||....
 Worm   332 NILHSGDVGIVICDEGHRLKNSENLTYQALSGLKCARRVLISGTPIQNDLLEYFSLVNFVNPGLL 396

  Fly   504 QDLQQWKKNLNESMLGHR-----------------RLNFIIKPLMLRRTKQKLQASGDMPALPSL 551
            ....:::|....::|..|                 .:..:::..::|||...|     ...||..
 Worm   397 GTASEFRKKFENAILKGRDADASSEDQKKGEEKTKEMISLVEKCIIRRTSALL-----TKYLPVK 456

  Fly   552 KIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNE 616
            ...:||.:.|..:..:|..|                                     :..|:.|.
 Worm   457 YEHIICCKNSTLQETLYNKL-------------------------------------IECEKQNR 484

  Fly   617 IYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQ 681
            |.|:          :|......|..:..|::.|.||.|:
 Worm   485 IVEK----------DKGATASALSFITHLKKLCNHPYLV-------------------------- 513

  Fly   682 LKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQ 746
                    .|:|.:.|:            |..|..|.:..:                   ||
 Worm   514 --------YDEFQKPDN------------RFRNKCLSIFPE-------------------SF--- 536

  Fly   747 LDSARALKLLNPQ--NPIFQFIRPSAKLKMVIDKLEELLTGTNDKIIVTSQWV----SYLAIVRK 805
                      ||:  :|.|     |.|:|::...|......|:||.::.|.:.    .::.:.:.
 Worm   537 ----------NPKSFDPSF-----SGKMKVLDYILAVTRKTTDDKFVLVSNYTQTIDQFMELCKL 586

  Fly   806 RLQDLSWETLDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWN 869
            |    .::.:..:|.::.|:|..::..|| ..:.....|||..|||.||||..||.:::.|..||
 Worm   587 R----GYDFVRLDGSMSIKQRSKIVDTFNDPASTIFCFLLSSKAGGCGLNLIGANRLVMFDPDWN 647

  Fly   870 PQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGL 934
            |..:.||..|::|.||.|..||||.:...::|:::...|..|..::..|: :.|.:|.:    ..
 Worm   648 PANDDQAMARVWRDGQKKMCFIYRLLATGSIEEKMFQRQTHKKALSSCVV-DAGEDVAR----HF 707

  Fly   935 NLAELKKLFEM 945
            :..:|::||::
 Worm   708 SSEQLRELFKL 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	142/763 (19%)
		DEAD-like_helicase_N	209..534	CDD:475120	64/371 (17%)
rad-54.L	NP_492438.1	HepA	<202..698	CDD:440319	143/765 (19%)
		DEAD-like_helicase_N	202..444	CDD:475120	64/371 (17%)