Protein Alignment CG10445 and chd-7

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_491426.2
• Gene: chd-7 / 172079
• WormBaseID: WBGene00007053
• Length: 2967
• Species: Caenorhabditis elegans
• Alignment Length: 1000
• Identity: 208/1000 - (20%)
• Similarity: 360/1000 - (36%)
• Gaps: 352/1000 - (35%)

  Fly    41 EPVDSLELSGEYADNESAIFVSASEYNEKKAQID--------QLVQKILTMEQQQRQLEENASET 97
            :|.|...:.|..:|:|...|:         .:||        .:|:|||.|  :..::|:...||
 Worm   950 DPTDEAGVEGAKSDDEDDEFL---------MKIDTPAPDPNAMVVEKILNM--RMGKVEKKVPET 1003

  Fly    98 KELCDLKLHLEKLNARLEALGEFLDTLRLREDQQEIKIE-----DNSELVDHTEQPKWSNLYSGL 157
                       ::....|..||       .:.::::|.|     :|.|.|.:.|..|
 Worm  1004 -----------EVAEGSEENGE-------EKSEEKVKKEPKENGENGESVGNGESSK-------- 1042

  Fly   158 NRYRQKANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQF 222
                                    .||..|       .:::|::..         :|..:||
 Worm  1043 ------------------------SKTESE-------TNEIEEEEV---------EQFLIKW--- 1064

  Fly   223 RERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKIS 287
            :.|..:...        .||.:.:..|....|.|.::.:.||.:..::..::||..:....|.:.
 Worm  1065 KGRSYVHCE--------WKTAAELLEIDKRVEAKIKRFKVKKMSSYIEDDEDFNSDFVIVDRVVD 1121

  Fly   288 MF--DDEEE--------SGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKD 342
            :.  ||.:|        .|.||..:||.|.    :...|:..:|     :....|.|.:.::|:
 Worm  1122 LITEDDGQEFVLIKWKSLGYEEVTWEPIEM----IPADKVELWR-----ERQVIDPAKIREKQR- 1176

  Fly   343 LLAKTPEPEVFSSDEEEEHLSNGR-----------------YPSANT------------------ 372
                 ||||.:......:...||.                 |.:.|.
 Worm  1177 -----PEPEEWKKMSTSKVWKNGNSLREYQFEGVDWLLYCYYNAQNCILADEMGLGKTVQTITFL 1236

  Fly   373 ------------LVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGP-------NRHEIGIEA---- 414
                        |||.|:|.:..|..|..:....|||   .:||.       .::|:..:.
 Worm  1237 SRIYDYGIHGPFLVVVPLSTIQNWVREFETWTDMNAI---VYHGSAYAREVLQQYEVFYDKRHCG 1298

  Fly   415 -------FRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHIIRNSKTNC---CNSVC 469
                   |...|.:||::..||::::.      |..:.|...::||||.::|  .||   .|.:.
 Worm  1299 AKNWKKNFVKIDALITTFETVVSDVEF------LKKIPWRVCVIDEAHRLKN--RNCKLLVNGLL 1355

  Fly   470 QLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQD----LQQWKKNLNESMLGHRRLNFIIKPL 530
            ..|......|||||:||...::|:||.|::...|.:    |:|:.....:..:  ::|..|:||:
 Worm  1356 AFRMEHRVLLTGTPLQNNIDELFSLLNFLHPQQFDNSATFLEQFGSCQTDDQV--QKLQEILKPM 1418

  Fly   531 MLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNY 595
            ||||.|:.::.|     |...:..:|.||||..:...|:   ||.::.|:...    ||.|
 Worm  1419 MLRRLKEDVEKS-----LGPKEETIIEVQLSDMQKKFYR---AILERNFSHLC----KGTS---- 1467

  Fly   596 YSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLR 660
                 .|.                                  ::.:::.||:.|.||.|:.|
 Worm  1468 -----APS----------------------------------LMNVMMELRKCCNHPFLING--- 1490

  Fly   661 GALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIK 725
                                       ||                            |.|.::.:
 Worm  1491 ---------------------------AE----------------------------EAIMNDFR 1500

  Fly   726 EENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKI 790
            ..:..||           |:.|    |.|.|         |:.|.|: ::|:||...|.....|:
 Worm  1501 LAHPDWD-----------EETL----AHKAL---------IQASGKV-VLIEKLLPKLRKDGHKV 1540

  Fly   791 IVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNANNEKR-VLLLSLTAGGVGLN 854
            ::.||.|..|.::.:.|..:|:.....:|.:....|:..:..|:..|..| |.||...|||:|:|
 Worm  1541 LIFSQMVKVLDLLEEFLISMSYPFERIDGNVRGDLRQAAIDRFSKENSDRFVFLLCTRAGGLGIN 1605

  Fly   855 LNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVL 919
            |..|:.::|.|..||||.:.|||.|.:|.||.|...:||.:..:|.|:.:......||.:.|.||
 Worm  1606 LTAADTVIIFDSDWNPQNDLQAQARCHRIGQKKLVKVYRLITSNTYEREMFDKASLKLGLDKAVL 1670

  Fly   920 PEEGGEVTKCVGGGLNLAELKKLFE 944
              :.....|..|..|:..::::|.:
 Worm  1671 --QSTTALKAEGTALSKKDVEELLK 1693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	186/893 (21%)
		DEAD-like_helicase_N	209..534	CDD:475120	86/406 (21%)
chd-7	NP_491426.2	Atrophin-1	<387..>666	CDD:460830
		PRK12323	<582..732	CDD:481241
		CD1_tandem_CHD5-9_like	979..1095	CDD:349315	31/194 (16%)
		CD2_tandem	1112..1162	CDD:349306	12/58 (21%)
		PLN03142	1197..>1803	CDD:215601	144/649 (22%)
		SANT	2073..2133	CDD:197842
		BRK	2672..2716	CDD:197800