Protein Alignment CG10445 and lds

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_061511887.1
• Gene: lds / 1280703
• VectorBaseID: AGAMI1_003319
• Length: 1197
• Species: Anopheles gambiae
• Alignment Length: 999
• Identity: 333/999 - (33%)
• Similarity: 490/999 - (49%)
• Gaps: 181/999 - (18%)

  Fly     1 MESSSP----SDTTEIHKQSCSIQDQSSVPVPDSSGEINNWMEPEP---------------VDSL 46
            ::|:||    |.:..:.::|..|...||   .|..||:....|..|               :.|.
Mosquito   322 VDSNSPAKDDSSSVRLIEKSEEILCLSS---SDDDGEVTFVEETRPSIDVKTRPQALVQPTITSF 383

  Fly    47 ELSGEYADNESAIFVSASEYNEKKAQIDQLVQKILTMEQQQRQL----EENASETKELCDLKLHL 107
            ..|.:.|.....  ||.|||:.|..::.:|..:::.::...|..    ::.|...:.|.::|..:
Mosquito   384 VRSQDTAQQRQR--VSQSEYDAKVRRMAELKSQVVMIDNVMRNSAKLPDKGAGLVRRLAEVKSQI 446

  Fly   108 EKLNARLEALGE-----FLDTLRLREDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRYRQKANHT 167
            .:|:..:|....     ...|::...|:.....:......||.   .|..:....:..:.:  ||
Mosquito   447 FELSKDIEMTRATPSKGIKKTIQRNFDENISGGDTKPRPADHI---SWDTIKRATDDIQPR--HT 506

  Fly   168 AAQ----FYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKHQQSCLKWMQFRERQKI 228
            ..|    |...|...:|.|:||::.|:..|:.|.|...|.||.:.|:.||:..|.||.:||.||.
Mosquito   507 GKQGIATFENQKLLTMDRLETLHKSIETCPSEDTLADPPKLLKIELMDHQRHALAWMLWRETQKP 571

  Fly   229 SGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEE 293
            .|||||||||||||||||:|:|.|.|
Mosquito   572 RGGILADDMGLGKTLSMISLVLKSAE--------------------------------------- 597

  Fly   294 ESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEE 358
                                         ||.|.......:..||::.|               |
Mosquito   598 -----------------------------LDPDGEQLERASESEDDEGD---------------E 618

  Fly   359 EEHLSNG--------RYPSANTLVVCPMSVMCQWAHEVASKVAQNAIRVLTFHGPNRHEIGIEAF 415
            |.|..||        .|.:..||:|||.|:|.||..|:.::|.:|::.|...||..| |......
Mosquito   619 ENHNPNGGWKSKGRKDYYAGGTLIVCPASLMRQWEGEITNRVKRNSLAVCVHHGTQR-ESKPRHL 682

  Fly   416 RSYDLVITSYNLVVNELKRYG---NTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHW 477
            ..||:|||:||||..| .|.|   ..|.::.|.|.|:||||||:|||.|:....:.|.|:....|
Mosquito   683 AKYDVVITTYNLVSRE-SRAGTARGASGVYGVNWERIILDEAHVIRNHKSAMSEACCGLKGRYRW 746

  Fly   478 ALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNL-NESMLGHRRLNFIIKPLMLRRTKQKLQA 541
            .|||||:||:.:||:||::|:....|.||..||:.: |::..|..|||.|:|.:||||||::||.
Mosquito   747 LLTGTPIQNKEMDVYALMKFLRCTPFNDLVHWKRWIDNKTAGGAMRLNTIMKSIMLRRTKKQLQE 811

  Fly   542 SGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFI- 605
            .|.:.:|||..||:|.|||.|.||.|||.:...||.:|.|||.||.:....:||......|.|.
Mosquito   812 RGALTSLPSKTIEIIEVQLEKDEMNVYQKVLMYSKHLFAQFLHQRAEKEHAINYGFGGARPTFSQ 876

  Fly   606 -AGHMSDERYNEIYERFLKSL-GYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDV 668
             |...:::.::::::: |||: ....|.::....||||||||||.||||||:..|    |:.:|.
Mosquito   877 RAHGGANQAFDKVHQK-LKSMHAAKDGSEVKQHQILVLLLRLRQVCCHPGLIYEM----LSDDDQ 936

  Fly   669 QNVKV-DASDVEGQL--KMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKEENVP 730
            .|:.: ...:.||..  ::|:|..|:|...:|.   ..|.|.....:|.      .|..|:|
Mosquito   937 SNLDMTGGGEEEGSFGAEVDLLGALNKLKLSDV---LADHEAKVAANGG------ADGSKQE--- 989

  Fly   731 WDSGDDLPTASSFEDQLDSARAL-----KLLNPQNPIFQFIRPSAKLKMVIDKLEELLTGTNDKI 790
                    .:.:..||.|...|:     |::...||||:..|||:|::..:..|||.:..|:||.
Mosquito   990 --------LSLNLSDQFDRPEAMAKAASKVMLKSNPIFRIERPSSKIEKTMQLLEEKIFHTDDKA 1046

  Fly   791 IVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFN-ANNEKRVLLLSLTAGGVGLN 854
            |:.|||.|.|.|:...|.:.:...:...|::..|.|..::.||| .:.:.:|:||||||||||||
Mosquito  1047 IIVSQWTSMLDILATHLSERNVPFVSLTGKVQVKFRNDIVLDFNKPSGKSKVMLLSLTAGGVGLN 1111

  Fly   855 LNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVL 919
            |..|||:|::|.|||||||.|||||:||.|||||.:|:::||.:||||:|::||:.||.||..||
Mosquito  1112 LVGANHLLLLDPHWNPQLEAQAQDRVYRVGQTKPVYIWKFMCAETVEQKIQALQEHKLGIADGVL 1176

  Fly   920 PEEGGEVTKCVGGGLNLAELKKLF 943
            .   |.|.|  |..|.:.:||.||
Mosquito  1177 T---GTVNK--GSKLTIDDLKSLF 1195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	294/838 (35%)
		DEAD-like_helicase_N	209..534	CDD:475120	115/336 (34%)
lds	XP_061511887.1	None