Protein Alignment CG10445 and LOC1273471

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_312449.5
• Gene: LOC1273471 / 1273471
• VectorBaseID: AGAMI1_011781
• Length: 1503
• Species: Anopheles gambiae
• Alignment Length: 1070
• Identity: 229/1070 - (21%)
• Similarity: 398/1070 - (37%)
• Gaps: 334/1070 - (31%)

  Fly     3 SSSPSDTTEIHKQSCSIQD----------QSSVP--------------VPDSSGEINNWMEPEPV 43
            :.:.||..|..|::.|..|          ::|:|              |.||..|.:......||
Mosquito   332 NENQSDVEEGSKRNESDSDAPITRGRNKSKTSIPKEKKNTLITRKRRAVSDSDEEQDTGKPSTPV 396

  Fly    44 -----DSLELSGEYADNESAIFVSASEYNEKKAQIDQL----VQKILTMEQQQRQLEENASETKE 99
                 |....||  :|.|.|...:|:..:::.|:..:.    ..|.......:...:|.|.  ||
Mosquito   397 ANGNTDKDSESG--SDFEFAKRNTATSRSQRAAERSKRGRAGATKAAAPSADEASNDEEAD--KE 457

  Fly   100 LCDLKLHLEKLNAR---LEALGEFLDTLRLREDQQEIKIEDNSELVDHTEQPKWSNLYSGLNRY- 160
            ..|.:...::...|   ..:.||....:..|:.:::.| :.||:....:......|:...|.:.
Mosquito   458 KNDFQTRKKRTRIRRNSTSSSGEDGKPVSKRKKRKQTK-KKNSDSEGDSPNKGRKNIRKLLKKSD 521

  Fly   161 RQKANHTAAQFYQHKSNIIDSLKTLYEPI---QPRPA---------IDDLEKQPAL----LLVRL 209
            .::....|.|..:.:...|...:.||..:   :|..|         .|:..|:|.|    .||:.
Mosquito   522 LEETTKNAEQEERERKQRIAERQKLYNQVYDEKPEEACTLDQLVLDFDEETKEPLLEVDRKLVKQ 586

  Fly   210 LK-HQ--------QSCLKWMQFRERQKISGGILADDMGLGKTLSMIAL---ILASEETKNRKREE 262
            || ||        .:|.:.::...:.|.||.|||..|||||||.::.|   :|||.:....:|..
Mosquito   587 LKPHQANGIKFMFDACFESLEQMNQSKGSGCILAHCMGLGKTLQVVTLAHTLLASADLTGVERIL 651

  Fly   263 KKKALT--LKWTQEFNRVYCKEIRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDD 325
            ....|:  |.|..||: ::.|.::|          |.|.|.||..:.:....:..|:.::.
Mosquito   652 VVCPLSTVLNWANEFH-MWMKHVKK----------GTEVEVYEISKYKDNVTRANKLMEWH---- 701

  Fly   326 DDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVAS 390
              |:.|...:..|..::|...|                                     |..:..
Mosquito   702 --NEGGVMIMGYDMFRNLANPT-------------------------------------ATRIRK 727

  Fly   391 KVAQNAIRVLTFHGPNRHEIGIEAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAH 455
            ||.::....|...||                         ||                ::.||.|
Mosquito   728 KVRESLQTSLIDPGP-------------------------EL----------------IVCDEGH 751

  Fly   456 IIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALL----------------RFVN-VPNF 503
            :::|.||:...:|.::.......|||||:||...:.:.::                |||| :.|.
Mosquito   752 LLKNEKTSLSQAVNRISTMRRIVLTGTPIQNNMKEYYCMVQFVKPKLLGTYTEYMNRFVNPITNG 816

  Fly   504 Q-------DLQQWKKNLNESMLGHRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIE-LICVQL 560
            |       |:|..:|..:   :.|:.|:..::    ||....|     .|.||. |:| ::.::|
Mosquito   817 QYTDSTPYDIQLMRKRAH---VLHKLLDGCVQ----RRDYAVL-----APFLPP-KLEFVVSIKL 868

  Fly   561 SKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLK-- 623
            :..:..:|:                         ||.     :.:||..:|:      :..||
Mosquito   869 TPLQSTLYK-------------------------YYM-----ENMAGKRNDD------DPTLKRS 897

  Fly   624 SLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVK------VDA-SDVEGQ 681
            |:.:|..:.:..|:....:||..                   .|...:|      :|: ::.||.
Mosquito   898 SMLFNDFQNLQRIWTHPRVLRYN-------------------SDRYEIKQQRKRDLDSENESEGS 943

  Fly   682 LKMDVLAELDKFDET----DSEDDCCDEEDSTRRD--------GNFKLEVIKDEIKEENVPWDSG 734
            :| |.:.:.|..:.|    |||.|.....|.:.||        .|.:...:.......|..::.|
Mosquito   944 MK-DFIDDEDTAESTPASSDSESDVQSVHDDSSRDAKSSGDSTSNKRKATVGTRSTRNNPNFNGG 1007

  Fly   735 DDLPTASSFEDQLDSARALKLLNPQNPI-----------FQFIRPSAKLKMVIDKLEELLTGTND 788
            ||       :|.:       :..|:||.           ...:..|.||.::::.|:| .....|
Mosquito  1008 DD-------DDVI-------MQKPENPTEWWMQMCPETELDNLEHSGKLVVLMEILKE-CEAIGD 1057

  Fly   789 KIIVTSQWVSYLAIVRKRLQDL--------------------SWET-LDF---NGQLTAKEREIV 829
            |::|.||.:..|.::...|..|                    ||.. ||:   :|..:...|...
Mosquito  1058 KLLVFSQSLYSLDVIEHFLSLLDENLQKDEDERDEQLSKYPGSWSLGLDYFRLDGSTSIDNRNDA 1122

  Fly   830 LRDFN--ANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIY 892
            .:.||  :|...|:.|:|..|||:|:||..||.::|.|:.|||..:.|:..|:||:||:||.:||
Mosquito  1123 CKVFNDESNTRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDIQSIFRVYRFGQSKPCYIY 1187

  Fly   893 RYMCQDTVEQRIKSLQDCKLEIAKVVLPEE 922
            |::...|:|::|...|..|..|:|.|:.|:
Mosquito  1188 RFIAMGTMEEKIYERQVTKQAISKRVIDEQ 1217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	199/922 (22%)
		DEAD-like_helicase_N	209..534	CDD:475120	74/362 (20%)
LOC1273471	XP_312449.5	None