Protein Alignment CG10445 and chd1

DIOPT Version :10

• Sequence 1: NP_649751.2
• Gene: CG10445 / 40938
• FlyBaseID: FBgn0037531
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_031749152.1
• Gene: chd1 / 100485675
• XenbaseID: XB-GENE-960477
• Length: 1797
• Species: Xenopus tropicalis
• Alignment Length: 984
• Identity: 203/984 - (20%)
• Similarity: 370/984 - (37%)
• Gaps: 296/984 - (30%)

  Fly     5 SPSDTTEIHK-QSCSIQDQSSVPVPDSSGEINNWMEPEPVDSLELSGEYADN--------ESAIF 60
            |.||....|| ::...|::|.|    .:|:.:...:....||.:  .:|.|:        ::.:.
 Frog   181 SESDYEPSHKVKNKKSQNRSKV----KNGKTSAGQKKRDADSSD--DDYDDDYNKRVSRRQATVN 239

  Fly    61 VSASEYNEKKAQIDQLVQKILTMEQQQRQLEENASETKE-LCDLKLHLEKLNA------RLEALG 118
            ||..|..|.|...|.|::.|   .:...|.||:..||.| :.|.:...:....      .:||.|
 Frog   240 VSYKEDEEMKTDSDDLLEVI---GEDVPQPEEDEFETIERVMDSRFGRKGATGGTTTIYAVEADG 301

  Fly   119 E----FLDTLRLREDQQEIK------IEDNSELVDHTEQPKWSNLYSGLNRYRQK---------- 163
            :    |.:|....|.|..:|      |.:..|..|..:|.....: ..|:.|::|
 Frog   302 DPNANFNETKEAGETQYLLKWKGWSSIHNTWETEDTLKQQNVKGM-KKLDNYKKKEQEKKRWLKA 365

  Fly   164 ANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEKQPALLLVRLLKH--QQSC-------LKW 219
            |:....::|..:..:||.|...|:.::                 |::.|  |:|.       .||
 Frog   366 ASPEDIEYYNCQQELIDDLHKQYQIVE-----------------RIIAHSNQKSAAGYPDYFCKW 413

  Fly   220 --MQFRERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKE 282
              :.:.|.....|.::|.     |..:.|...::..::|....:|                 ||.
 Frog   414 QGLPYSECSWEDGALIAK-----KFQARIDEYISRNQSKTIPFKE-----------------CKV 456

  Fly   283 IRKISMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDND-------AGDKAVVEDEQ 340
            :             |:..::...:|:..::...|..:.|....|..:       .|:..::.||.
 Frog   457 L-------------KQRPRFVALKKQPSYIGGNKQLELRDYQLDGLNWLAHSWCKGNSCILADEM 508

  Fly   341 KDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEV-------------ASKV 392
            .  |.||.:...|.:....||...|.:     |:|.|:|.:..|..|:             ....
 Frog   509 G--LGKTIQTISFLNYLFHEHQLYGPF-----LLVVPLSTLTSWQREIQIWAPLMNAVVYLGDIN 566

  Fly   393 AQNAIRVLTFHGPNRHEIGIEAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHII 457
            ::|.||...:..|....:.:      ::::|:|.:::.:      .|.|..|.|..:.:||||.:
 Frog   567 SRNMIRTHEWMHPQTKRLKL------NVLLTTYEILLKD------KSFLGGVNWAFIGVDEAHRL 619

  Fly   458 RNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESM-LGHR 521
            :|..:....::...:::....:||||:||...::::||.|:....|...:.:::...:.. .|:.
 Frog   620 KNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYA 684

  Fly   522 RLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQR 586
            .|:..::|.:|||.|:.::.|  :||    |:|    |:.:.||:.       |:|.:.:::|.|
 Frog   685 SLHKELEPFLLRRVKKDVEKS--LPA----KVE----QILRVEMSA-------SQKQYYKWILTR 732

  Fly   587 EKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCH 651
                   ||.:|.:                             |.|
 Frog   733 -------NYKALSK-----------------------------GSK------------------- 742

  Fly   652 PGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFK 716
                 |...|.|                     :::.||.|         ||:.
 Frog   743 -----GSTSGFL---------------------NIMMELKK---------CCNH----------- 761

  Fly   717 LEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFIRPSAKLKMVIDKLEE 781
            ..:||.  .|||                         :..|.|..:...||.|.|| :::|||..
 Frog   762 CYLIKP--PEEN-------------------------EFYNRQEALQHLIRSSGKL-ILLDKLLV 798

  Fly   782 LLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNA-NNEKRVLLLS 845
            .|....:::::.||.|..|.|:.:.|:...:.....:|.:..:.|:..|..||| .:|....|||
 Frog   799 RLRERGNRVLIFSQMVRMLDILAEYLKSRQFPFQRLDGSIKGEVRKQALDHFNAEGSEDFCFLLS 863

  Fly   846 LTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDC 910
            ..|||:|:||..|:.::|.|..||||.:.|||.|.:|.||.|...|||.:.:.:||:.|......
 Frog   864 TRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDIIERAKK 928

  Fly   911 KLEIAKVVL 919
            |:.:..:|:
 Frog   929 KMVLDHLVI 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10445	NP_649751.2	HepA	<113..919	CDD:440319	174/858 (20%)
		DEAD-like_helicase_N	209..534	CDD:475120	64/356 (18%)
chd1	XP_031749152.1	CD1_tandem_CHD1-2_like	270..354	CDD:349313	18/84 (21%)
		CD2_tandem_CHD1-2_like	387..443	CDD:349308	12/77 (16%)
		PLN03142	464..>1000	CDD:215601	138/639 (22%)
		CDH1_2_SANT_HL1	1123..1208	CDD:477096
		DUF4208	1491..1581	CDD:464035
		U2AF_lg	1669..>1778	CDD:273727
		HisXaaSer_A3	<1705..1744	CDD:439608