DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2678 and AgaP_AGAP004830

DIOPT Version :9

Sequence 1:	NP_649750.1	Gene:	CG2678 / 40937	FlyBaseID:	FBgn0014931	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	XP_001688568.1	Gene:	AgaP_AGAP004830 / 4576427	VectorBaseID:	AGAP004830	Length:	508	Species:	Anopheles gambiae

Alignment Length:	395	Identity:	88/395 - (22%)
Similarity:	136/395 - (34%)	Gaps:	93/395 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AKNVCRTCMDETGTLVDIFANVRDPVLDEPEMSLSHILARCTERPVKRGDLLPQFICVSCVLAVQ 69
            |.::||.||. |..|.|||.      .|.|......|:..||...:...|.||..||..|:..|:
Mosquito   162 ALDMCRVCMG-TEELSDIFQ------FDGPVRVSDIIMKVCTNIRITARDHLPHKICEQCLGQVR 219

  Fly    70 NAFRFKWQSEQSYQHFFRVLNQSGAPENQVHLAACNGDKNQ----IINQKMQLKSDRQQDTQQMT 130
            ....||.:.|.|.:...:.|.:|           .|..:.|    ::|..|   ||..:|.::..
Mosquito   220 IVNEFKNRCEASDKELRKNLKRS-----------TNKSRRQSEVIVVNCPM---SDSDKDDEEPV 270

  Fly   131 KTQKPDDD---LSQKQTLQAKLQEGNIDGPPESFTLHPRKRTCRT--EEQADMIPKEATRSTKMI 190
                 |||   :||.:.........:...||......|::|..|.  ..:....||....||...
Mosquito   271 -----DDDEYKVSQSEVESEPATSDDSFSPPNKRKRTPKRRVGRPPGRGRPGRKPKNMVVSTPKF 330

  Fly   191 CDADG-----------------YYNCPHCSKRFCSQTQL---RTHITDLCNRCPYCPRTYMQKSN 235
            ....|                 |...|..|.....:.::   |....|  |.||.|......:..
Mosquito   331 AVKRGPGRPPKYPKTSSLTNIVYIEAPEDSSSSGEEAEVTPKRRKRGD--NPCPKCDEVLPSQLA 393

  Fly   236 LKRHLRNHLSKPAHK--CFHCSKAFMRKDHLKRHLRTHDSDGPLSCSQCSAVFIEHVQLEIHRRE 298
            ||:||:.|   |..:  |..|:..|..:..|..|:..|.....:.              |..|:|
Mosquito   394 LKQHLKTH---PGDRFDCDRCALFFRTEKALSNHIERHKKADKIR--------------EEKRKE 441

  Fly   299 HKQRPGSSKSESTKDPDSDDSDQAQDLKPKWTKNTFNGTCSIPPMLKPKPIC-----DI--CQKK 356
            .:||   .:..|...|.|.|:::::.:.|:       |:.:.....|.:|..     |:  |...
Mosquito   442 REQR---IEQRSRYTPKSSDAEKSKLISPQ-------GSATAEKKKKSEPSAASSGRDLFKCVAP 496

  Fly   357 FSSVY 361
            .:|.|
Mosquito   497 LTSTY 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2678	NP_649750.1	zf-AD	8..85	CDD:214871	25/76 (33%)
		COG5048	220..>284	CDD:227381	16/65 (25%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		zf-C2H2	249..271	CDD:278523	5/23 (22%)
		C2H2 Zn finger	251..271	CDD:275368	5/19 (26%)
		C2H2 Zn finger	279..299	CDD:275368	2/19 (11%)
		C2H2 Zn finger	350..370	CDD:275368	4/19 (21%)
		C2H2 Zn finger	379..399	CDD:275368
		C2H2 Zn finger	406..427	CDD:275368
AgaP_AGAP004830	XP_001688568.1	zf-AD	165..237	CDD:214871	25/78 (32%)
		C2H2 Zn finger	381..401	CDD:275371	7/19 (37%)
		C2H2 Zn finger	408..429	CDD:275371	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910