DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2678 and Odj

DIOPT Version :9

Sequence 1:	NP_649750.1	Gene:	CG2678 / 40937	FlyBaseID:	FBgn0014931	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_650661.1	Gene:	Odj / 42145	FlyBaseID:	FBgn0038551	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	89/451 - (19%)
Similarity:	158/451 - (35%)	Gaps:	136/451 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 CRTCMDETGTLVDIFANVRDPVLDEPEMSLSHILARCTERPVKRGDLLPQFICVSCVLAVQNAFR 73
            ||.|.:.      ||......:.::....:...:.:.|...:...::|||.||..|:|.:..|..
  Fly     5 CRICGER------IFTPHPKNIFEKRNHRIRMAIEQITGLEIVLENMLPQHICACCLLDLTQAVA 63

  Fly    74 FKWQSEQSYQHFF-RVLNQSG-APENQVHLAACNGD---KNQIINQKMQLKSDRQ--QDTQQMTK 131
            |:.:..:::.:.. |:.:::| |.:....::....|   |.::::..:..:.|::  .|.:.:.
  Fly    64 FRQRCLETHANLHQRISSKAGVASKGSPEVSPVLSDPLLKREVLDDTVDTEDDKELLDDDKDLM- 127

  Fly   132 TQKPDDDLSQKQTLQAKLQEGNIDGPPESFTLHPRKRTCRTEEQADMIPKEATRSTKMICDADGY 196
                |||   |..|:        |..|  ...:|..:..|.|:|
  Fly   128 ----DDD---KDFLE--------DEKP--ILRYPPAKKIRIEDQ--------------------- 154

  Fly   197 YNCPHCSKRFCSQTQLRTHITDLCNRCPYCPRTYMQKSNLKRHLRNHLSKP-------AHKCFHC 254
             |.|:.........:||..:.:..:..|..||.:::|...:|      .||       .:.|..|
  Fly   155 -NFPNRQSPRVRVKRLRVPVVEKADSPPPPPREHVRKPRKRR------PKPKVDRSIKRYVCDQC 212

  Fly   255 SKAF----MRKDHLKRHLRTHDSDGPLSCSQCSAVFIEHVQLEIHRREHKQRPGSSKSESTKDPD 315
            ..:|    ..|||..||.     :...||.:|...|.....|.:|.|.|      .|.|
  Fly   213 GWSFNDHSNMKDHKLRHF-----EEKFSCDECGRKFYTMPLLRLHIRVH------HKGE------ 260

  Fly   316 SDDSDQAQDLKPKWTKNTFNGTCSIPPMLKPKP-ICDICQKKFSSVYALKRHMLTHNRQHHLKK- 378
                                           || :|..|...|::..:..|    |.||.|..:
  Fly   261 -------------------------------KPYVCKFCGMGFANSPSRCR----HERQMHANEL 290

  Fly   379 ---CTYCSEEFKTEKHLKRHERGHMG---DLFRCEFCSLVFVDVNYLRK------HKKRIH 427
               |..|.:.|.:||...:||.||..   |:..|..|:..|.:..:|.:      |:||::
  Fly   291 VHPCKICGKRFNSEKGRLKHEEGHKSDQPDVHICLTCNKEFKEAQFLHRHYSTKYHRKRVN 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2678	NP_649750.1	zf-AD	8..85	CDD:214871	15/75 (20%)
		COG5048	220..>284	CDD:227381	18/74 (24%)
		C2H2 Zn finger	223..243	CDD:275368	5/19 (26%)
		zf-C2H2	249..271	CDD:278523	8/25 (32%)
		C2H2 Zn finger	251..271	CDD:275368	8/23 (35%)
		C2H2 Zn finger	279..299	CDD:275368	6/19 (32%)
		C2H2 Zn finger	350..370	CDD:275368	4/19 (21%)
		C2H2 Zn finger	379..399	CDD:275368	7/19 (37%)
		C2H2 Zn finger	406..427	CDD:275368	7/26 (27%)
Odj	NP_650661.1	zf-AD	5..77	CDD:214871	15/77 (19%)
		COG5048	<202..343	CDD:227381	42/192 (22%)
		C2H2 Zn finger	209..229	CDD:275368	6/19 (32%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		zf-H2C2_2	249..274	CDD:290200	11/67 (16%)
		C2H2 Zn finger	265..283	CDD:275368	5/21 (24%)
		C2H2 Zn finger	298..314	CDD:275368	5/15 (33%)
		zf-C2H2_jaz	322..347	CDD:288983	4/24 (17%)
		C2H2 Zn finger	324..343	CDD:275368	4/18 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910