DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2678 and CG9609

DIOPT Version :9

Sequence 1:	NP_649750.1	Gene:	CG2678 / 40937	FlyBaseID:	FBgn0014931	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	83/345 - (24%)
Similarity:	129/345 - (37%)	Gaps:	74/345 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 QLKSDRQQDTQQMTKTQKPDDDLSQKQTLQAKLQEGNIDGPPESFTLHPRKRTCRTEEQADMIPK 181
            |:.||...:|..        ::..|:|.     :..:|.....:.::...:.|.:..:|.|....
  Fly     6 QIASDSDMETAL--------EEFKQRQG-----RRNSIGSAKYACSMPKCEATFKRLDQLDRHEY 57

  Fly   182 EATRSTKMICDADGYYNCPHCSKRFCSQTQLRTHITDLCNR----------CPY--CPRTYMQKS 234
            ..|...|..|..:|      |.|.:...|.|:.|:.....|          |..  |.:.::..|
  Fly    58 HHTGIKKHACSYEG------CDKTYSIVTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVS 116

  Fly   235 NLKRHLR-NHLSKPAHKCFHCSKAFMRKDHLKRH-LRTHDSDGPLSCSQCSAVFIEHVQLEIHRR 297
            |:.||:| .|.|...:.|..||..|.:|..|||| :|.|..:.|.|||:||..|.:..|.:.|
  Fly   117 NMTRHMRETHESPKVYPCSQCSAKFSQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQWQCQSH-- 179

  Fly   298 EHKQRPGSSKSESTKDPDSDDSDQAQDLKPKWT------KNTFNGTCSIPPMLKPKPICDICQKK 356
                .|.....|....|...|         |||      :::.:|        |.:..||.|...
  Fly   180 ----EPSCKLYECPGCPLQFD---------KWTLYTKHCRDSLHG--------KNRHKCDRCDSA 223

  Fly   357 FSSVYALKRHM-LTHNRQHHLKKCT---YCSEE-----FKTEKHLKRHE-RGHMGDLFRCEF--C 409
            |.....||||: :.|.......:|.   .|:||     :...::|::|. ..|.|..|.|:.  |
  Fly   224 FDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAHSGRRFECQALDC 288

  Fly   410 SLVFVDVNYLRKHKKRIHSN 429
            ...|.....|.:|..|.|.:
  Fly   289 GRCFSSAQNLARHLLRDHKD 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2678	NP_649750.1	zf-AD	8..85	CDD:214871
		COG5048	220..>284	CDD:227381	26/77 (34%)
		C2H2 Zn finger	223..243	CDD:275368	7/22 (32%)
		zf-C2H2	249..271	CDD:278523	10/22 (45%)
		C2H2 Zn finger	251..271	CDD:275368	10/20 (50%)
		C2H2 Zn finger	279..299	CDD:275368	7/19 (37%)
		C2H2 Zn finger	350..370	CDD:275368	8/20 (40%)
		C2H2 Zn finger	379..399	CDD:275368	6/28 (21%)
		C2H2 Zn finger	406..427	CDD:275368	6/22 (27%)
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	3/18 (17%)
		zf-C2H2_8	67..150	CDD:292531	24/88 (27%)
		C2H2 Zn finger	67..90	CDD:275368	7/28 (25%)
		C2H2 Zn finger	106..126	CDD:275368	6/19 (32%)
		C2H2 Zn finger	134..155	CDD:275368	10/20 (50%)
		C2H2 Zn finger	188..210	CDD:275368	5/30 (17%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..276	CDD:275368	5/22 (23%)
		C2H2 Zn finger	283..302	CDD:275368	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100