DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2678 and CG11398

DIOPT Version :9

Sequence 1:	NP_649750.1	Gene:	CG2678 / 40937	FlyBaseID:	FBgn0014931	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster

Alignment Length:	299	Identity:	75/299 - (25%)
Similarity:	107/299 - (35%)	Gaps:	95/299 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 DDDLS-QKQTLQ-------AKLQEGNIDGPPESFTLHPRKRTC-----RTEEQADMIPK------ 181
            |::|| ..:.||       ::.|:|   |.| ||..    |.|     ..||.|...|.
  Fly    21 DEELSLNTEELQFEELNERSQHQQG---GSP-SFVC----RRCPALFLTREELAAHRPTHRYQGG 77

  Fly   182 EATRSTKMICDADGYYNCPHCSKRFCSQTQLRTHI---TDLCN-RCPYCPRTYMQKSNLKRHLRN 242
            :.|.:::..|||        |.:.|.....|..|:   .|:.| .||.||..::|:||.:.||:|
  Fly    78 QQTPASEHACDA--------CGRVFQKHNALVDHMNAHNDVRNYPCPECPARFVQRSNRECHLKN 134

  Fly   243 -HLSKPAHKCFH--CSKAFMRKDHLKRHLRT-HDSDGPLSCSQCSAVFIEHVQLEIHRREHKQRP 303
             |.....|.|..  |.|.|.::....:|::| |.::..|.|..|||.|...|....|...|
  Fly   135 VHRKVYLHSCPEPGCKKRFQQRRECDQHVKTVHQNERNLVCDTCSARFSHPVNYRKHLASH---- 195

  Fly   304 GSSKSESTKDPDSDDSDQAQDLKPKWTKNTFNGTCSIPPMLKPKPICDICQKKFSSVYALKRHML 368
            ||:||..                                       |.||.|.|........|:.
  Fly   196 GSAKSYG---------------------------------------CPICGKLFGRPENRDVHLF 221

  Fly   369 THNRQHHLKK---CTYCSEEFKTEKHLKRH--ERGHMGD 402
            .|:    :.|   |:.|..::.....|.||  ..||..|
  Fly   222 VHS----ICKAYICSVCGADYMRRNQLIRHGLASGHHND 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2678	NP_649750.1	zf-AD	8..85	CDD:214871
		COG5048	220..>284	CDD:227381	23/68 (34%)
		C2H2 Zn finger	223..243	CDD:275368	10/20 (50%)
		zf-C2H2	249..271	CDD:278523	7/24 (29%)
		C2H2 Zn finger	251..271	CDD:275368	6/22 (27%)
		C2H2 Zn finger	279..299	CDD:275368	7/19 (37%)
		C2H2 Zn finger	350..370	CDD:275368	6/19 (32%)
		C2H2 Zn finger	379..399	CDD:275368	5/21 (24%)
		C2H2 Zn finger	406..427	CDD:275368
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	6/23 (26%)
		C2H2 Zn finger	87..107	CDD:275368	7/27 (26%)
		C2H2 Zn finger	115..136	CDD:275368	10/20 (50%)
		C2H2 Zn finger	144..165	CDD:275368	5/20 (25%)
		C2H2 Zn finger	175..195	CDD:275368	7/19 (37%)
		C2H2 Zn finger	203..223	CDD:275368	6/19 (32%)
		C2H2 Zn finger	231..247	CDD:275368	3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100