DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2678 and Opbp

DIOPT Version :9

Sequence 1:	NP_649750.1	Gene:	CG2678 / 40937	FlyBaseID:	FBgn0014931	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	78/379 - (20%)
Similarity:	115/379 - (30%)	Gaps:	122/379 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LPQFICVSCVLAVQNAFRFKWQSEQSYQHFFRVLNQSGAPENQVHLAACNGDKNQIINQKMQLKS 120
            |.||.|..|              .:|:......:::      |:|....:.....|.|:|.:
  Fly   221 LDQFYCEIC--------------NKSFDETLLTVHK------QMHQQESSEIMCSICNRKFE--- 262

  Fly   121 DRQQDTQQMTKT--QKPDDDLSQKQTLQAKLQEGNIDGPPESFTLHPRKRTCRTEEQADMIPKEA 183
              .:.|.||.:.  :||.|..|.::..|                     ||...:|:..
  Fly   263 --NEVTYQMHQKIHEKPRDSESSRKLAQ---------------------RTSLDKEKPG------ 298

  Fly   184 TRSTKMICDADGYYNCPHCSKRFCSQTQL----RTHITDLCNRCPYCPRTYMQKSNLKRHLRNHL 244
                         :.|.:|.:.|....:.    |.|..:....|..|.:|:....:|..|||.|.
  Fly   299 -------------FPCQYCERVFTRPFEKVKHERVHTGEKPYACEVCGKTFRVSYSLTLHLRTHT 350

  Fly   245 SKPAHKCFHCSKAFMRKDHLKRHLRTHDSDGPLSCSQCSAVFIEHVQLEIHRREHKQRPGSSKSE 309
            :...:.|..|:|.|........|||.|.|:...||..|...|...|||..|:..|
  Fly   351 NIRPYVCTVCNKRFKSHQVYSHHLRIHSSERQFSCDACPKTFRTSVQLYAHKNTH---------- 405

  Fly   310 STKDPDSDDSDQAQDLKPKWTKNTFNGTCSIPPMLKPKPI-CDICQKKFSSVYALKRHMLTHNRQ 373
                                                .||. |.:|.:.|||:||:|.||.||...
  Fly   406 ------------------------------------TKPYRCAVCNRPFSSMYAVKNHMQTHKEI 434

  Fly   374 HHLKKCTYCSEEFKTEKHLKRHERGHMGDLFRCEFCSLVFVDVNYLRKHKKRIH 427
            .........:...|:....|....|.    |.|..|...:..:..||.|.|..|
  Fly   435 SSKGSVGSGTPNIKSAATSKSQAAGK----FYCNTCGAEYARLFALRLHMKSAH 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2678	NP_649750.1	zf-AD	8..85	CDD:214871	6/28 (21%)
		COG5048	220..>284	CDD:227381	20/63 (32%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		zf-C2H2	249..271	CDD:278523	7/21 (33%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		C2H2 Zn finger	279..299	CDD:275368	7/19 (37%)
		C2H2 Zn finger	350..370	CDD:275368	10/19 (53%)
		C2H2 Zn finger	379..399	CDD:275368	2/19 (11%)
		C2H2 Zn finger	406..427	CDD:275368	6/20 (30%)
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	6/24 (25%)
		C2H2 Zn finger	301..321	CDD:275368	4/19 (21%)
		zf-H2C2_2	316..336	CDD:290200	4/19 (21%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		zf-H2C2_2	341..366	CDD:290200	9/24 (38%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	411..431	CDD:275368	10/19 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100