DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2678 and ZSCAN29

DIOPT Version :9

Sequence 1:NP_649750.1 Gene:CG2678 / 40937 FlyBaseID:FBgn0014931 Length:434 Species:Drosophila melanogaster
Sequence 2:NP_001359009.1 Gene:ZSCAN29 / 146050 HGNCID:26673 Length:852 Species:Homo sapiens


Alignment Length:470 Identity:94/470 - (20%)
Similarity:157/470 - (33%) Gaps:147/470 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 SHILARCTERPVKRGDLLPQFICVSCVLAVQNAFRFKWQSEQSYQ--HFFRVLN-----QSGAPE 96
            |.:.....||..:.|.|.....|.:...::|.::| |.::.|:.:  .||..::     :..||.
Human   439 SQLYGAVAERLWEYGFLRTPEQCRTKFKSLQTSYR-KVKNGQAPETCPFFEEMDALVSVRVAAPP 502

  Fly    97 N--QVHLAACNGDKNQIINQKMQLKSDRQQDTQQMTKTQKPDDDLSQKQTLQAKLQEGNIDGPP- 158
            |  |...|:|.      :....:.::.:|.:.......:..|||            |.:.:.|| 
Human   503 NDGQEETASCP------VQGTSEAEAQKQAEEADEATEEDSDDD------------EEDTEIPPG 549

  Fly   159 -------------------------------ESFTLH-----------PR--------KRTCRT- 172
                                           |...||           ||        :..||: 
Human   550 AVITRAPVLFQSPRGFEAGFENEDNSKRDISEEVQLHRTLLARSERKIPRYLHQGKGNESDCRSG 614

  Fly   173 --------EEQADM-IPKEA---TRSTKMICDADGYYNCPHCSKRFCSQTQLR---THITDLCNR 222
                    |::..: :|:::   ..|.:..|..:..|.....||.|...:.|.   :|..:...:
Human   615 RQWAKTSGEKRGKLTLPEKSLSEVLSQQRPCLGERPYKYLKYSKSFGPNSLLMHQVSHQVENPYK 679

  Fly   223 CPYCPRTYMQKSNLKRHLRNHLSKPAHKCFHCSKAFMRKDHLKRHLRTHDSDGPLSCSQCSAVFI 287
            |..|.:::.:.:.|.||.|.|..:..:||..|.|:|....:...|.|.|..:.|..|.:|...|.
Human   680 CADCGKSFSRSARLIRHRRIHTGEKPYKCLDCGKSFRDSSNFITHRRIHTGEKPYQCGECGKCFN 744

  Fly   288 EHVQLEIHRREHKQRPGSSKSESTKDPDSDDSDQAQDLKPKWTKNTFNGTCSIPPMLKPKPI-CD 351
            :...|.||:|.|...                                            ||. |:
Human   745 QSSSLIIHQRTHTGE--------------------------------------------KPYQCE 765

  Fly   352 ICQKKF--SSVYALKRHMLTHNRQHHLKKCTYCSEEFKTEKHLKRHERGHMGDL-FRCEFCSLVF 413
            .|.|.|  ||.::..|.:.|..|.|   .|..|.:.|.....|:.|.|.|.|:. :.|..|...|
Human   766 ECGKSFNNSSHFSAHRRIHTGERPH---VCPDCGKSFSKSSDLRAHHRTHTGEKPYGCHDCGKCF 827

  Fly   414 VDVNYLRKHKKRIHS 428
            ...:.|.||.: ||:
Human   828 SKSSALNKHGE-IHA 841

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2678NP_649750.1 zf-AD 8..85 CDD:214871 10/47 (21%)
COG5048 220..>284 CDD:227381 18/63 (29%)
C2H2 Zn finger 223..243 CDD:275368 6/19 (32%)
zf-C2H2 249..271 CDD:278523 7/21 (33%)
C2H2 Zn finger 251..271 CDD:275368 6/19 (32%)
C2H2 Zn finger 279..299 CDD:275368 7/19 (37%)
C2H2 Zn finger 350..370 CDD:275368 7/21 (33%)
C2H2 Zn finger 379..399 CDD:275368 6/19 (32%)
C2H2 Zn finger 406..427 CDD:275368 6/20 (30%)
ZSCAN29NP_001359009.1 SCAN 14..124 CDD:128708
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 96..182
Myb_DNA-bind_4 245..330 CDD:372747
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 347..400
Myb_DNA-bind_4 408..493 CDD:372747 12/54 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 502..557 11/72 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 603..625 3/21 (14%)
COG5048 <630..838 CDD:227381 59/254 (23%)
C2H2 Zn finger 680..700 CDD:275368 6/19 (32%)
C2H2 Zn finger 708..728 CDD:275368 6/19 (32%)
C2H2 Zn finger 736..756 CDD:275368 7/19 (37%)
C2H2 Zn finger 764..784 CDD:275368 7/19 (37%)
C2H2 Zn finger 792..812 CDD:275368 6/19 (32%)
C2H2 Zn finger 820..840 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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