Protein Alignment Prat and ADE4

DIOPT Version :10

• Sequence 1: NP_524271.2
• Gene: Prat / 40935
• FlyBaseID: FBgn0004901
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_014029.1
• Gene: ADE4 / 855346
• SGDID: S000004915
• Length: 510
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 163/515 - (31%)
• Similarity: 252/515 - (48%)
• Gaps: 66/515 - (12%)

  Fly    54 CGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNVH--KGMGMISTLF 116
            ||:.|.:....   ...:|..:|.|.:.||||||::|||||    |.....::  ||.||...:|
Yeast     2 CGILGIVLANQ---TTPVAPELCDGCIFLQHRGQDAAGIAT----CGSRGRIYQCKGNGMARDVF 59

  Fly   117 NDDSMKKLRGNLGIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNGELVNNESLRR---EVLA 178
            ....:..|.|::||.|.||.|||.|.....|||.|::.:| :.|||||.|||..||:|   |.:.
Yeast    60 TQQRVSGLAGSMGIAHLRYPTAGSSANSEAQPFYVNSPYG-INLAHNGNLVNTASLKRYMDEDVH 123

  Fly   179 RGVGLSTHSDSELIAQSLCCAPEDVSELDGPNWPARIRHFMMLAPL---------SYSLVIMLKD 234
            |.:  :|.|||||:....      .:||:..| ..|:.:..:...|         .|:.|.:|..
Yeast   124 RHI--NTDSDSELLLNIF------AAELEKHN-KYRVNNEDVFHALEGVYRLCRGGYACVGLLAG 179

  Fly   235 -KIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTPADGWVVSSESCGFLSIGARYVREVEPGEIVE 298
             .::..||..|.|||..|:        ..|.|...| ::::|||..|.:......|:::|||.|.
Yeast   180 FALFGFRDPNGIRPLLFGE--------RENPDGTKD-YMLASESVVFKAHNFTKYRDLKPGEAVI 235

  Fly   299 LSRSGYRTVDIVERPDFKRMAFC------IFEYVYFARGDSIFEGQMVYTVRLQCGRQLWRE--- 354
            :.::..:     ..|:||::...      :||||||||.||:.:|..||..||..|.:|...
Yeast   236 IPKNCSK-----GEPEFKQVVPINSYRPDLFEYVYFARPDSVLDGISVYHTRLAMGSKLAENILK 295

  Fly   355 --APVEADIVSSVPESGTAAAHGYARESGIEFAEVLCRNRYVGRTFIQPSTRLRQLGVAKKFGAL 417
              .|.:.|:|..||::....|...|...|..:.|...:|||||||||.|:.|.|...|.:|...:
Yeast   296 QLKPEDIDVVIPVPDTARTCALECANVLGKPYREGFVKNRYVGRTFIMPNQRERVSSVRRKLNPM 360

  Fly   418 SENVAGKRLVLIDDSIVRGNTIGPIIKLLRDAGAREVHIRIASPPLQYPCYMGINIPTREELIAN 482
            .....||:::::|||||||.|...|:.:.:::||.:|:...|:|.::|....||::...:.|||.
Yeast   361 ESEFKGKKVLIVDDSIVRGTTSKEIVNMAKESGATKVYFASAAPAIRYNHIYGIDLTDTKNLIAY 425

  Fly   483 KLNPDQLARHVGADSLAYLSVEGLVEAVQLKHRDAGDSKSKGTGHCTACLTGEYPGGLPD 542
            ....:::|..:|.:.:.|.|:|.|::..:         ..|.|.......||.|..|:.|
Yeast   426 NRTDEEVAEVIGCERVIYQSLEDLIDCCK---------TDKITKFEDGVFTGNYVTGVED 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prat	NP_524271.2	PurF	49..545	CDD:439804	163/515 (32%)
ADE4	NP_014029.1	PurF	1..486	CDD:439804	163/515 (32%)