Protein Alignment Prat and Ppat

DIOPT Version :10

• Sequence 1: NP_524271.2
• Gene: Prat / 40935
• FlyBaseID: FBgn0004901
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_742158.1
• Gene: Ppat / 231327
• MGIID: 2387203
• Length: 517
• Species: Mus musculus
• Alignment Length: 529
• Identity: 324/529 - (61%)
• Similarity: 392/529 - (74%)
• Gaps: 30/529 - (5%)

  Fly    36 MESESISASKELTGLTHECGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCS 100
            ||.|.:       |:..||||||.||.||||||:|:.|||.||||.|||||||||||.||:|...
Mouse     1 MELEEL-------GIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSAV 58

  Fly   101 KNFNVHKGMGMISTLFNDDSMKKL-RGNLGIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNG 164
            ..|.||||||:::.:|.:|::||| ..|||||||||:|.|...:.|||||.|.|.||.:|:||||
Mouse    59 PKFRVHKGMGLVNHVFTEDNLKKLYDSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNG 123

  Fly   165 ELVNNESLRREVLARGVGLSTHSDSELIAQSLCCAPEDVSELDGPNWPARIRHFMMLAPLSYSLV 229
            ||||...||:::|.:|:||||.||||:|.|.|...|....: |.|:|.|||::.|..||.:||||
Mouse   124 ELVNAARLRKKLLRQGIGLSTSSDSEMITQLLAYTPPQEKD-DAPDWVARIKNLMKEAPAAYSLV 187

  Fly   230 IMLKDKIYAVRDTYGNRPLCIGKIVPI-NAGHGNNLDTPADGWVVSSESCGFLSIGARYVREVEP 293
            ||.:|.||||||.|||||||||:::|: :........:..:|||||||||.||||||||..||:|
Mouse   188 IMHRDFIYAVRDPYGNRPLCIGRLMPVSDVNDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKP 252

  Fly   294 GEIVELSRSGYRTVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQMVYTVRLQCGRQLWREAPVE 358
            |||||:||.|.||:||:.|.:...:||||||||||||.||:||.|||||||.:||:||..|||||
Mouse   253 GEIVEISRHGIRTLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAIEAPVE 317

  Fly   359 ADIVSSVPESGTAAAHGYARESGIEFAEVLCRNRYVGRTFIQPSTRLRQLGVAKKFGALSENVAG 423
            ||:||:||||.|.||.|||.:.|:.:.||||:|||||||||||:.||||||||||||.||:|..|
Mouse   318 ADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKG 382

  Fly   424 KRLVLIDDSIVRGNTIGPIIKLLRDAGAREVHIRIASPPLQYPCYMGINIPTREELIANKLNPDQ 488
            ||:|||||||||||||.||||||:::||:|||||:||||::|||:|||||||:|||||||...|.
Mouse   383 KRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDC 447

  Fly   489 LARHVGADSLAYLSVEGLVEAVQ----------LKHRDAGDSKSKG------TGHCTACLTGEYP 537
            ||.::||:|:.||||||||.:||          .||..|......|      ||||||||||:|
Mouse   448 LAEYLGANSVVYLSVEGLVSSVQQEIKFKKQKVKKHDIAIQENGNGLEYFEKTGHCTACLTGQY- 511

  Fly   538 GGLPDELSW 546
               |.||.|
Mouse   512 ---PVELEW 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prat	NP_524271.2	PurF	49..545	CDD:439804	319/513 (62%)
Ppat	NP_742158.1	PurF	7..516	CDD:439804	319/513 (62%)