Protein Alignment Prat and ppat-1

DIOPT Version :10

• Sequence 1: NP_524271.2
• Gene: Prat / 40935
• FlyBaseID: FBgn0004901
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_497958.1
• Gene: ppat-1 / 175613
• WormBaseID: WBGene00011407
• Length: 480
• Species: Caenorhabditis elegans
• Alignment Length: 500
• Identity: 235/500 - (47%)
• Similarity: 329/500 - (65%)
• Gaps: 42/500 - (8%)

  Fly    54 CGVFGAIACGDWPTQMDIAHVICL---GLVALQHRGQESAGIATSEGKCSKNFNVHKGMGMISTL 115
            ||:||.:|.|::      .|:..|   ||.||||||.||.|:..|:|....:..:.||.|::..:
 Worm     2 CGIFGIVAAGNY------EHLNVLAANGLAALQHRGTESTGLVGSDGITRDHVEIIKGHGLVRDV 60

  Fly   116 FNDDSMKKLRG-NLGIGHTRYSTAG--GSGVVNC-QPFEVHTTHGALALAHNGELVNNESLRREV 176
            ..:|::.::.| ::.|||.||||||  .|| :|| |||.|:|..|.:|:|||||||:.:..|:||
 Worm    61 ITEDNISRMNGQSIIIGHNRYSTAGKKKSG-INCVQPFVVYTAMGTVAIAHNGELVDAKQKRKEV 124

  Fly   177 LARGVGLSTHSDSELIAQSL---------CCAPEDVSELDGPNWPARIRHFMMLAPLSYSLVIML 232
            |..||||||.:|||||||.:         |...:::.::     ...:...|....:||||::|.
 Worm   125 LHEGVGLSTDTDSELIAQMIAKAIALNVKCKYGQEMGDI-----TRELAVTMSALNMSYSLLVMT 184

  Fly   233 KDKIYAVRDTYGNRPLCIGKIVPINAGHGNNLDTPADGWVVSSESCGFLSIGARYVREVEPGEIV 297
            .|::||:||.:||||||:|.:...|   ||     .:.::.|||||.| ...|:...||.|||||
 Worm   185 FDRLYAIRDPFGNRPLCVGTVYSKN---GN-----PEAFIASSESCAF-PANAKLDFEVRPGEIV 240

  Fly   298 ELSRSGYRTVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQMVYTVRLQCGRQLWREAPVEADIV 362
            |||..|.::|..: :|: ..:|.||||||||||.||..|||.|.|||.:||:.:..|..:|||||
 Worm   241 ELSTGGIKSVWQM-KPN-TPLAMCIFEYVYFARNDSEIEGQQVQTVREECGKTMALEDDLEADIV 303

  Fly   363 SSVPESGTAAAHGYARESGIEFAEVLCRNRYVGRTFIQPSTRLRQLGVAKKFGALSENVAGKRLV 427
            .:||:|..:||.|||.:|||.:..||.||.||||:||:|:..:||..:..|||.|.:.:.|:|:|
 Worm   304 GNVPDSSLSAAIGYASQSGITYEPVLHRNSYVGRSFIEPNDEMRQNAIKMKFGVLKKKIHGQRIV 368

  Fly   428 LIDDSIVRGNTIGPIIKLLRDAGAREVHIRIASPPLQYPCYMGINIPTREELIANKLNPDQLARH 492
            |:|||||||||:..::|:||||||:|||:||||||:::||:|||||||.:||||.:....::.:.
 Worm   369 LVDDSIVRGNTMRTLVKMLRDAGAKEVHLRIASPPVKFPCFMGINIPTTKELIAAEKTIPEICQF 433

  Fly   493 VGADSLAYLSVEGLVEAVQLKHRDAGDSKSKGTGHCTACLTGEYP 537
            |||||:.||||:|||.:||   :....:.:...|||||||||:||
 Worm   434 VGADSVRYLSVDGLVSSVQ---KGIERAANFSPGHCTACLTGKYP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prat	NP_524271.2	PurF	49..545	CDD:439804	234/499 (47%)
ppat-1	NP_497958.1	PurF	1..479	CDD:439804	234/499 (47%)