Protein Alignment EMC1 and EMC1

DIOPT Version :10

• Sequence 1: NP_649747.1
• Gene: EMC1 / 40933
• FlyBaseID: FBgn0037530
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: XP_061499262.1
• Gene: EMC1 / 1274314
• VectorBaseID: AGAMI1_012064
• Length: 929
• Species: Anopheles gambiae
• Alignment Length: 920
• Identity: 487/920 - (52%)
• Similarity: 627/920 - (68%)
• Gaps: 22/920 - (2%)

  Fly    12 LALLLGTCSALYEDQIKKFDWRGVNVGALKQSRVDLNHFQPRILVTTYEGVVASLCVKTGELVWR 76
            ||.||.|||.||||||.|||||...||.:.....|.:... ||:|.|...|:|::..|||:::||
Mosquito    16 LAALLSTCSGLYEDQIGKFDWRQQYVGKIVDGAFDTSSVD-RIIVATESNVLAAISAKTGDILWR 79

  Fly    77 QVLEQKPRGDVKLLQVSGFADDSSDTAAAPMGSNMGFDMLTVQGHAPALVRGWNTNMGALEWEWS 141
            ||||..|||.||||.|   |:.||..|....|.|.|.|::||.|..||||||||:|:|.||||||
Mosquito    80 QVLENGPRGTVKLLHV---ANPSSTGARLNRGGNAGHDIITVSGSNPALVRGWNSNLGTLEWEWS 141

  Fly   142 IMP-MNTERAQDAMWIYSKSVLYHVLPAWRSHLEVTAYFASSGHSTGS-TSKVIAPWITSESCTL 204
            ::| :..|.|..|:|.....:||||:|.|.||||||.|.|.||....| ||::.|.||..|.|.|
Mosquito   142 LLPSVAEEAASAAVWFEHDGLLYHVVPVWGSHLEVTPYQAVSGQQARSTTSRIAAGWIAKERCAL 206

  Fly   205 SGTFYVCTDGKQLISLDLVS-KSGQVIRTSLEAEPKGKTQALTGLNGVVIVDGKPISVNKDQSIC 268
            :|:|:.|...:||::|||.: .|..|:...|.:|..|:.:|:.| ...||.:|:..::..||.:.
Mosquito   207 AGSFFACGIKEQLLALDLAADASSTVVSKPLGSEAVGRPKAVRG-EAAVIQNGRYYALRSDQKLA 270

  Fly   269 ---GDLRSSSFAVGSFNYRKVLAYADLSSGILRINALYLDNCAPAAELEQSLPFPEHFGTPSLSN 330
               .|.......|.......:....|.:|..|.|||..|.:.|...::|.|..|.|..|.|.|..
Mosquito   271 FGPNDAALVDRMVQEGEPILLQGVVDRASNKLTINAHRLRDFARFEQIEISTDFSETLGDPDLVA 335

  Fly   331 FDCKQKRNGEGKN--------CLFLFSSTSESIVAVQHGRVRWSREESLANVIDSQFVDLPLADT 387
            ..|||. :|.|.:        |..|.|:...:||.:|.|:::|.|||:||.|..:.|:||.|:|.
Mosquito   336 IRCKQS-SGSGSSRAGTAGLVCRVLLSTEDGAIVLLQQGKIKWVREEALAEVETADFLDLTLSDA 399

  Fly   388 EGTLENEMKGKAGDFTSFERDIASAFLRRITTQAVQIRSLFLHVIGLGPPPTDTQRAGLVRDSFG 452
            ||.:|.|:..|..:....|.|:..|..||||.|.:.:::||||::|:||.|:..||||||||.||
Mosquito   400 EGAIEEELNNKNAEENGPEWDVFGALQRRITAQVLHVKNLFLHILGVGPAPSKAQRAGLVRDDFG 464

  Fly   453 LHKMLVLLTRAGKIFGIDNVSGKHHWQLHLPNVIGFANDEQMRLIVQRSAKHFPLQPLCTILGKN 517
            ||||||::|.:||:||||||||||||..:||:..||.|.:.|:|:|||:::.:||...|.|||:.
Mosquito   465 LHKMLVVVTSSGKVFGIDNVSGKHHWVRYLPSFTGFGNGQPMKLLVQRTSRFYPLPAQCVILGRQ 529

  Fly   518 AVSG-NGVLYRFNPITGK-VAEGGLVQLDYRIKQLSLLGETEKDFLKGILLLDASNKVHVYPEHA 580
            .... ||:||.||||||: |..||||:|.||::|:|||.:|..|||||:||||..|..||.||..
Mosquito   530 KHGARNGLLYIFNPITGQPVVGGGLVELPYRVQQVSLLHQTGPDFLKGLLLLDYDNNAHVVPESL 594

  Fly   581 APLADGMYLYTADLKTAELAGYFVKYAGGQLSSTHIWNARLGGHNSEQQIIGVAGKNPIEHVHSQ 645
            |..||..||:|.|.:.|::.|:.|:|..|:|.:...|...|.|....||||...||:||||||||
Mosquito   595 AVHADNYYLFTTDQRGAQMRGFLVQYRAGRLETVPTWQIDLSGAGKSQQIIACEGKSPIEHVHSQ 659

  Fly   646 GRVLGDRSVLYKYINPNLVAFVTQAPDSTHKSVLNLYLVDVVSGSVVFTMTHRKVRAPLSIVHSE 710
            |||:.|||||||||||||||..|..||:.||.:||::||||||||:||:|:|:::|.||.:||||
Mosquito   660 GRVMADRSVLYKYINPNLVAVATHGPDNIHKYILNVHLVDVVSGSIVFSMSHKRIRPPLHMVHSE 724

  Fly   711 NWLAYSYFNEKLRRTEITTIELYEGKSQANSSVWSSLQAPPMPLVERQSYILPTIVEALRETITE 775
            |||.|||:|:|.||||:|:|||||||:|.||:|||||.|||:|:|||||||||..|.||:|||||
Mosquito   725 NWLVYSYYNDKARRTEMTSIELYEGKTQTNSTVWSSLDAPPLPMVERQSYILPMAVAALKETITE 789

  Fly   776 RGITNKHVLIGTASGSIVEMPWHLLDPRRPIASTTQGREEGAIPYIPELPLPTESHINYNQTVAR 840
            :|||:||:|||..:|::.||.|.|||||||:.|..:.||||.:||:||||||.|..|||||||..
Mosquito   790 KGITSKHILIGLTTGAVAEMTWALLDPRRPVTSPEKAREEGIVPYMPELPLPHEILINYNQTVTH 854

  Fly   841 LRNIYTAPSGLESTCLVVATGLDLFVTRVAPSKTFDLLKEDFDYILISIVLVALTSGSLIVKHLA 905
            :|.|:||||||||||||:..|||||||||:||||||||||||||.||::|||.||:.|.:||.||
Mosquito   855 IRGIHTAPSGLESTCLVLVHGLDLFVTRVSPSKTFDLLKEDFDYFLITVVLVVLTTTSFVVKQLA 919

  Fly   906 SRKLLKQAWK 915
            |:||:|||||
Mosquito   920 SKKLVKQAWK 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EMC1	NP_649747.1	EMC1_C	709..914	CDD:462261	145/204 (71%)
EMC1	XP_061499262.1	None