Protein Alignment wtrw and pain

DIOPT Version :9

• Sequence 1: NP_731193.1
• Gene: wtrw / 40931
• FlyBaseID: FBgn0260005
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: NP_611979.1
• Gene: pain / 37985
• FlyBaseID: FBgn0060296
• Length: 913
• Species: Drosophila melanogaster
• Alignment Length: 1036
• Identity: 214/1036 - (20%)
• Similarity: 373/1036 - (36%)
• Gaps: 327/1036 - (31%)

  Fly    71 EYMECGPSPPAESAPSMYDSFEEPTSELSVQICNDTLR--ISLIDQMKSAAGRVKLFEDIEQSNV 133
            ::..||              |.:|.::|:..:....:|  ::.:|     :|.:...:|...:::
  Fly     2 DFNNCG--------------FIDPQAQLAGALAKQDIRQFVAALD-----SGALADLQDDRHTSI 47

  Fly   134 VAEGIRTHFESASKLEKNLCYLWAAYLKRWDLIESLLEAGADLHF----CDQNGISALHLSAFSG 194
            ..:.:.|..          |.         |.||:.::.|:.:::    .|:..||....|...|
  Fly    48 YEKALSTPG----------CR---------DFIEACIDHGSQVNYINKKLDKAAISYAADSRDPG 93

  Fly   195 CLATLGLLVAKGLNVNLQSKC--YTPLHCAAFGNAAEAA-------KLLINNGADISKDTSKPNC 250
            .||.| |....|..|.:..|.  .|||:..|.....|.|       :||::.||       .||.
  Fly    94 NLAAL-LKYRPGNKVQVDRKYGQLTPLNSLAKNLTDENAPDVYSCMQLLLDYGA-------SPNI 150

  Fly   251 ----EESLLHCAVRSNAL-----ECLQIFIAE-GADVNSLKPNGTNAIHLAADLGNIQCLEALLN 305
                |.:.||..:|.:.:     |.:|:|:.. ..|::|.: ||.....|.|....::..|....
  Fly   151 VDQGEFTPLHHVLRKSKVKAGKKELIQLFLDHPELDIDSYR-NGEVRRLLQAQFPELKLPEERHT 214

  Fly   306 APNAD-ANVRICIREKEST------------------------------ALHLAADEGNVECVDL 339
            .|..| ..::..:|:.:.|                              .|..:...|.....|:
  Fly   215 GPEIDIQTLQRTLRDGDETLFEQQFAEYLQNLKGGADNQLNAHQEEYFGLLQESIKRGRQRAFDV 279

  Fly   340 LLAKGADAKLKNHRGFTPLHLAARTSSLDCVESLLRNGNADA----NAEDFDHRTP----LHAAV 396
            :|:.|.|.   |.|       ..|.:..:.||:.:..||..|    ..|.....||    |:|.:
  Fly   280 ILSTGMDI---NSR-------PGRANEANLVETAVIYGNWQALERLLKEPNLRLTPDSKLLNAVI 334

  Fly   397 GK-SENAYD------IMETLIQWG-ANVNHKDIYGFTALHLAALDGLVQCVEMLIFHGADVTTKS 453
            |: .|..||      ..|.||... .::|..|......|..|........::.|:.:||.:.:||
  Fly   335 GRLDEPPYDGSSHQRCFELLINSDRVDINEADSGRLVPLFFAVKYRNTSAMQKLLKNGAYIGSKS 399

  Fly   454 KKGTSALNVITRKTPASVAMIRQKLDAAITLHHSQDPVNREVELELDFRQLLQHCHPREISYLNT 518
            ..||..:    :..|..|  :.:..|:.||. :.:.|.::..|:.:|::.|::.   ...|.||.
  Fly   400 AFGTLPI----KDMPPEV--LEEHFDSCITT-NGERPGDQNFEIIIDYKNLMRQ---ERDSGLNQ 454

  Fly   519 FVDE-----------GQKEILEHPLCSSFLYIKWGKIRKYYIGRLIFCFSFVLFLTLYVLTALAH 572
            ..||           ..:.:|:|||.||||::||.::      .:||..:|::: :|:..:.:.:
  Fly   455 LQDEMAPIAFIAESKEMRHLLQHPLISSFLFLKWHRL------SVIFYLNFLIY-SLFTASIITY 512

  Fly   573 NCYNGSKNDNTTIPAQELCQKQSILGDMLRNNPFVMEMQW-------------WVLVAITIVEIF 624
            ......::|...:.|                  |...:.|             |::..:
  Fly   513 TLLKFHESDQRALTA------------------FFGLLSWLGISYLILRECIQWIMSPV------ 553

  Fly   625 RKLYGITGYSSFRHYVTQVENIMEWFVIT-SVFV-ISYIYTNKTYTFQNHIGAFAVLLGWTNLML 687
                         .|...:.||||..:|| |:|. :...:..:|   |..:..|.:||......|
  Fly   554 -------------RYFWSITNIMEVALITLSIFTCMESSFDKET---QRVLAVFTILLVSMEFCL 602

  Fly   688 MIGQLPVFDV--YVAMYTRVQGEFAKLFMAYSCMLIGFTISFCVIFPSS---------------- 734
            ::|.|||..:  ::.|...|...|.|.|..||..::.|::.|.::|..|
  Fly   603 LVGSLPVLSISTHMLMLREVSNSFLKSFTLYSIFVLTFSLCFYILFGKSVEEDQSKSATPCPPLG 667

  Fly   735 -----------SSFANPFMGFITVLVMMIGEQDLSLLINDPEGKDPPFLLEVSAQITFVLFLLFV 788
                       ::|..|....|..:||:.||.|...:          ....:...:.|:||::|:
  Fly   668 KKEGKDEEQGFNTFTKPIEAVIKTIVMLTGEFDAGSI----------QFTSIYTYLIFLLFVIFM 722

  Fly   789 TIILMNLLVGIAVHDIQGLKKTAGLSKLVRQTKLISYIESALFN----GYLPTWLRNLLHYTALV 849
            ||:|.|||.|:||.|.|.:|..|.|:..:.:|.::|..|..|..    |:|   |.|.|..:
  Fly   723 TIVLFNLLNGLAVSDTQVIKAQAELNGAICRTNVLSRYEQVLTGHGRAGFL---LGNHLFRS--- 781

  Fly   850 SPQAYRVVLCVKPLNPSEKRLPREILMKAYEVGKMRKHFGHTISSKNSAENYLSYKN-KYNNNNG 913
                    :|.:             ||..|                   .||||.:. ....|:|
  Fly   782 --------ICQR-------------LMNIY-------------------PNYLSLRQISVLPNDG 806

  Fly   914 ATTGYVLPDSDPDAGQFTTLTTKIDDNADRIEFLTQEIQELKQALISQQQQASKVIDKLLI 974
              ...::|.|||                       .|::.||:|...|...::.|..|.|:
  Fly   807 --NKVLIPMSDP-----------------------FEMRTLKKASFQQLPLSAAVPQKKLL 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wtrw	NP_731193.1	Ank_2	156..241	CDD:289560	26/97 (27%)
		ANK repeat	182..213	CDD:293786	10/30 (33%)
		ANK repeat	215..242	CDD:293786	10/35 (29%)
		ANK	216..341	CDD:238125	33/172 (19%)
		ANK repeat	250..281	CDD:293786	9/40 (23%)
		Ank_2	255..351	CDD:289560	23/132 (17%)
		ANK repeat	283..317	CDD:293786	7/34 (21%)
		ANK	323..443	CDD:238125	31/165 (19%)
		ANK repeat	323..351	CDD:293786	7/57 (12%)
		Ank_2	325..420	CDD:289560	27/110 (25%)
		ANK repeat	353..385	CDD:293786	7/35 (20%)
		ANK repeat	387..420	CDD:293786	12/44 (27%)
		Ank_2	392..>460	CDD:289560	20/75 (27%)
		ANK repeat	422..452	CDD:293786	5/29 (17%)
		Ion_trans	613..812	CDD:278921	55/229 (24%)
pain	NP_611979.1	ANK	56..180	CDD:238125	35/150 (23%)
		ANK repeat	82..111	CDD:293786	10/29 (34%)
		ANK repeat	113..152	CDD:293786	12/45 (27%)
		ANK	303..406	CDD:238125	26/102 (25%)
		Ank_2	303..398	CDD:289560	22/94 (23%)
		ANK repeat	324..366	CDD:293786	12/41 (29%)
		ANK repeat	368..393	CDD:293786	3/24 (13%)
		Ion_trans	525..746	CDD:278921	58/270 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810